Published in:
Open Access
01-12-2010 | Poster presentation
Relating protease inhibitor resistance at time of virological failure with drug exposure
Authors:
M Van Luin, WP Bannister, R Paredes, AN Phillips, J Bruun, J Van Lunzen, O Kirk, A d'Arminio Monforte, A Cozzi-Lepri, DM Burger
Published in:
Journal of the International AIDS Society
|
Special Issue 4/2010
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Excerpt
The absence of detectable HIV resistance after treatment failure may result from non-adherence, especially for drugs such as ritonavir-boosted PIs (PI/r) for which minimum adherence may be sufficient to achieve suppression. This analysis aimed to investigate the association between adherence, indicated by a detectable PI plasma concentration, and development of PI resistance in patients presenting with virological failure of a PI/r regimen. …