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Journal of the International AIDS Society
Published in: Journal of the International AIDS Society 4/2010

Open Access 01-12-2010 | Poster presentation

The use of a darunavir/ritonavir once-daily regimen in two pregnant women

Authors: JS Lambert, LJ Else, V Jackson, L Dickinson, DJ Back, M Brennan, C Weldridge, S Coulter-Smith, S Gibbons, SH Khoo

Published in: Journal of the International AIDS Society | Special Issue 4/2010

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Excerpt

Darunavir (DRV) is a second generation protease inhibitor (PI), first licensed for use in 2006. It is indicated for use in a treatment experienced population and is effective in vitro against both wild type and PI-resistant HIV. As a relatively new drug there is little published information on the pharmacokinetics of darunavir in pregnancy. Here we examine the pharmacokinetics of darunavir/ritonavir [DRV/r 800/100mg once daily (OD)] in two women, over the course of pregnancy and postpartum. …
Metadata
Title
The use of a darunavir/ritonavir once-daily regimen in two pregnant women
Authors
JS Lambert
LJ Else
V Jackson
L Dickinson
DJ Back
M Brennan
C Weldridge
S Coulter-Smith
S Gibbons
SH Khoo
Publication date
01-12-2010
Publisher
BioMed Central
DOI
https://doi.org/10.1186/1758-2652-13-S4-P189

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Developed by: Springer Medicine

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