Published in:
Open Access
01-05-2014 | Oral presentation
Updated results and correlative FDG-PET analysis of a phase IB study of vemurafenib and cobimetinib (MEK inhibitor [GDC-0973]), in advanced BRAF
V600
- mutated melanoma (BRIM7)
Authors:
Igor Puzanov, Grant McArthur, Rene Gonzalez, Anna Pavlick, Omid Hamid, Thomas F Gajewski, Ming Yin, Jill Fredrickson, Nicholas Choong, Antoni Ribas
Published in:
Journal of Translational Medicine
|
Special Issue 1/2014
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Excerpt
BRIM7 is a phase 1B study evaluating the safety and efficacy of combined BRAF and MEK inhibition with vemurafenib + cobimetinib. The utility of FDG-PET as an early predictor of clinical benefit was also evaluated in this study. …