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Published in: Journal of Translational Medicine 1/2014

Open Access 01-05-2014 | Oral presentation

Updated results and correlative FDG-PET analysis of a phase IB study of vemurafenib and cobimetinib (MEK inhibitor [GDC-0973]), in advanced BRAF V600 - mutated melanoma (BRIM7)

Authors: Igor Puzanov, Grant McArthur, Rene Gonzalez, Anna Pavlick, Omid Hamid, Thomas F Gajewski, Ming Yin, Jill Fredrickson, Nicholas Choong, Antoni Ribas

Published in: Journal of Translational Medicine | Special Issue 1/2014

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Excerpt

BRIM7 is a phase 1B study evaluating the safety and efficacy of combined BRAF and MEK inhibition with vemurafenib + cobimetinib. The utility of FDG-PET as an early predictor of clinical benefit was also evaluated in this study. …
Metadata
Title
Updated results and correlative FDG-PET analysis of a phase IB study of vemurafenib and cobimetinib (MEK inhibitor [GDC-0973]), in advanced BRAF V600 - mutated melanoma (BRIM7)
Authors
Igor Puzanov
Grant McArthur
Rene Gonzalez
Anna Pavlick
Omid Hamid
Thomas F Gajewski
Ming Yin
Jill Fredrickson
Nicholas Choong
Antoni Ribas
Publication date
01-05-2014
Publisher
BioMed Central
Published in
Journal of Translational Medicine / Issue Special Issue 1/2014
Electronic ISSN: 1479-5876
DOI
https://doi.org/10.1186/1479-5876-12-S1-O7

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