Published in:
Open Access
01-05-2014 | Oral presentation
Revealing cancer initiating cells in metastatic melanomas by harnessing the host′s anti tumor humoral immune mechanisms
Authors:
Beatrix Kotlan, Gabriella Liszkay, Gyorgy Naszados, Judit Olasz, Szabolcs Horvath, Klara Eles, Miri Blank, Yehuda Shoenfeld, Laszlo Gobor, Laszlo Toth, Orsolya Csuka, Maria Godeny, Miklos Kasler, Francesco M Marincola
Published in:
Journal of Translational Medicine
|
Special Issue 1/2014
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Excerpt
To determine whether the growth of tumors is sustained by the whole cancer cell population or it is maintained only by small fraction of cancer initiating cells, has crucial impact on the design of suitable therapies. That is why the research on defining the subpopulation of cancer initiating cancer stem cells (CSC) in solid tumors has come into highlights. …