Published in:
Open Access
01-05-2014 | Oral presentation
Efficacy of radiotherapy in patients on progression after treatment with ipilimumab 3 mg/kg
Authors:
Antonio M Grimaldi, Ester Simeone, Diana Giannarelli, Paolo Muto, Sara Falivene, Fabio Sandomenico, Antonella Petrillo, Marcello Curvietto, Assunta Esposito, Miriam Paone, Marco Palla, Corrado Caracò, Gennaro Ciliberto, Nicola Mozzillo, Paolo A Ascierto
Published in:
Journal of Translational Medicine
|
Special Issue 1/2014
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Excerpt
Ipilimumab, a fully human monoclonal antibody (IgG1) that promote antitumor immunity by blocking CTLA4, was the first agent which showed a long-term survival benefit, about the 20% of patients, for the treatment of metastatic melanoma. The combination of ipilimumab with other therapies might improve its efficacy. …