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Open Access 01-12-2006 | Review

Current trends in the management of extra-abdominal desmoid tumours

Authors: Panayiotis J Papagelopoulos, Andreas F Mavrogenis, Evanthia A Mitsiokapa, Kleo Th Papaparaskeva, Evanthia C Galanis, Panayotis N Soucacos

Published in: World Journal of Surgical Oncology | Issue 1/2006

Abstract

Extra-abdominal desmoid tumours are slow-growing, histologically benign tumours of fibroblastic origin with variable biologic behaviour. They are locally aggressive and invasive to surrounding anatomic structures. Magnetic resonance imaging is the modality of choice for the diagnosis and the evaluation of the tumours. Current management of desmoids involves a multidisciplinary approach. Wide margin surgical resection remains the main treatment modality for local control of the tumour. Amputation should not be the initial treatment, and function-preserving procedures should be the primary treatment goal. Adjuvant radiation therapy is recommended both for primary and recurrent lesions. Chemotherapy may be used for recurrent or unresectable disease. Overall local recurrence rates vary and depend on patient's age, tumour location and margins at resection.

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Title: Current trends in the management of extra-abdominal desmoid tumours
Authors: Panayiotis J Papagelopoulos
Andreas F Mavrogenis
Evanthia A Mitsiokapa
Kleo Th Papaparaskeva
Evanthia C Galanis
Panayotis N Soucacos
Publication date: 01-12-2006
Publisher: BioMed Central
Published in: World Journal of Surgical Oncology / Issue 1/2006
Electronic ISSN: 1477-7819
DOI: https://doi.org/10.1186/1477-7819-4-21

At a glance: The STEP trials

Springer Medicine

Current trends in the management of extra-abdominal desmoid tumours

Abstract

At a glance: The STEP trials

Springer Medicine

Abstract

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