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Published in: World Journal of Surgical Oncology 1/2006

Open Access 01-12-2006 | Correspondence

Rituximab induced hypoglycemia in non-Hodgkin's lymphoma

Authors: Badrudeen M Hussain, N Geetha, V Lali, Manoj Pandey

Published in: World Journal of Surgical Oncology | Issue 1/2006

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Abstract

Background

Hypoglycemia is a vary rare toxicity of rituximab. The exact mechanism of rituximab induced hypoglycemia is not clear.

Case presentation

A 50 year old female presented with a left tonsillar non Hodgkin's lymphoma and was started on R-CHOP chemotherapy. Twenty four hours after the first rituximab infusion, she developed hypoglycemia which was managed by IV glucose infusion.

Conclusion

Hypoglycemia following rituximab administration is rare. Possibilities of hypoglycemia should be kept in mind in patients developing symptoms like fatigue, restlessness, and sweating while on rituximab therapy.
Literature
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go back to reference IDEC Pharmaceuticals/Genentech: Rituximab prescribing information. 2002, San Diego/South San Francisco, CA IDEC Pharmaceuticals/Genentech: Rituximab prescribing information. 2002, San Diego/South San Francisco, CA
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go back to reference Hematology-Oncology. Medscape DrugInfo with First Databank and ASHP. Rituximab intraven Adverse Effects List & Discussion. Hematology-Oncology. Medscape DrugInfo with First Databank and ASHP. Rituximab intraven Adverse Effects List & Discussion.
3.
go back to reference Coll AP, Thomas S, Mufti GJ: Rituximab therapy for the type B syndrome of severe insulin resistance. N Engl J Med. 2004, 350: 310-311. 10.1056/NEJM200401153500324.CrossRefPubMed Coll AP, Thomas S, Mufti GJ: Rituximab therapy for the type B syndrome of severe insulin resistance. N Engl J Med. 2004, 350: 310-311. 10.1056/NEJM200401153500324.CrossRefPubMed
Metadata
Title
Rituximab induced hypoglycemia in non-Hodgkin's lymphoma
Authors
Badrudeen M Hussain
N Geetha
V Lali
Manoj Pandey
Publication date
01-12-2006
Publisher
BioMed Central
Published in
World Journal of Surgical Oncology / Issue 1/2006
Electronic ISSN: 1477-7819
DOI
https://doi.org/10.1186/1477-7819-4-89

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