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Published in: World Journal of Surgical Oncology 1/2012

Open Access 01-12-2012 | Technical innovations

Total thyroidectomy with ultrasonic dissector for cancer: multicentric experience

Authors: Roberto Cirocchi, Carlo Boselli, Salvatore Guarino, Alessandro Sanguinetti, Stefano Trastulli, Jacopo Desiderio, Alberto Santoro, Fabio Rondelli, Giovanni Conzo, Domenico Parmeggiani, Giuseppe Noya, Giorgio De Toma, Nicola Avenia

Published in: World Journal of Surgical Oncology | Issue 1/2012

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Abstract

Background

We conducted an observational multicentric clinical study on a cohort of patients undergoing thyroidectomy for thyroid carcinoma. The aim of this study was to evaluate the benefits of the use of ultrasonic dissector (UAS) vs. the use of a conventional technique (vessel clamp and tie) in patients undergoing thyroid surgery for cancer.

Methods

From June 2009 to May 2010 we evaluated 321 consecutive patients electively admitted to undergo total thyroidectomy for thyroid carcinoma. The first 201 patients (89 males, 112 females) presenting to our Department underwent thyroidectomy with the use of UAS while the following 120 patients (54 males, 66 females) underwent thyroidectomy performed with a conventional technique (CT): vessel clamp and tie.

Results

The operative time (mean: 75 min in UAS vs. 113 min in CT, range: 54 to 120 min in UAS vs. 68 to 173 min in CT) was much shorter in the group of thyroidectomies performed with UAS. The incidence of transient laryngeal nerve palsy (UAS 3/201 patients (1.49%); CT 1/120 patients (0.83%)) was higher in the group of UAS; the incidence of permanent laryngeal nerve palsy was similar in the two groups (UAS 2/201 patients (0.99%) vs. CT 2/120 patients (1.66%)). The incidence of transient hypocalcaemia (UAS 17/201 patients (8.4%) vs. CT 9/120 patients (7.5%)) was higher in the UAS group; no relevant differences were reported in the incidence of permanent hypocalcaemia in the two groups (UAS 5/201 patients (2.48%) vs. 2/120 patients (1.66%)). Also the average postoperative length of stay was similar in two groups (2 days).

Conclusion

The only significant advantage proved by this study is represented by the cost-effectiveness (reduction of the usage of operating room) for patients treated with UAS, secondary to the significant reduction of the operative time. The analysis failed to show any advantages in terms of postoperative transient complications in the group of patients treated with ultrasonic dissector: transient laryngeal nerve palsy (1.49% in UAS vs. 0.83% in CT) and transient hypocalcaemia (8.4% in UAS vs. 7.5%in CT). No significant differences in the incidence of permanent laryngeal nerve palsy (0.8% in UAS vs. 1.04% in CT) and permanent hypocalcaemia (2.6% in UAS vs. 2.04% in CT) were demonstrated. The level of surgeons’ expertise is a central factor, which can influence the complications rate; the use of UAS can only help surgical action but cannot replace the experience of the operator.
Literature
1.
go back to reference Ellis H: Thyroid and parathyroid. The Cambridge illustrated history of surgery. Edited by: Ellis H. 2009, Cambridge University Press, Cambridge, 195-209. Ellis H: Thyroid and parathyroid. The Cambridge illustrated history of surgery. Edited by: Ellis H. 2009, Cambridge University Press, Cambridge, 195-209.
2.
go back to reference Iacconi P, Bendinelli C, Miccoli P: Endoscopic thyroid and parathyroid surgery. Surg Endosc. 1999, 13: 314-315. 10.1007/s004649900976.CrossRefPubMed Iacconi P, Bendinelli C, Miccoli P: Endoscopic thyroid and parathyroid surgery. Surg Endosc. 1999, 13: 314-315. 10.1007/s004649900976.CrossRefPubMed
3.
go back to reference Heniford BT, Matthews BD, Sing RF, Backus C, Pratt B, Greene FL: Initial results with an electrothermal bipolar vessel sealer. Surg Endosc. 2001, 15: 799-801. 10.1007/s004640080025.CrossRefPubMed Heniford BT, Matthews BD, Sing RF, Backus C, Pratt B, Greene FL: Initial results with an electrothermal bipolar vessel sealer. Surg Endosc. 2001, 15: 799-801. 10.1007/s004640080025.CrossRefPubMed
4.
go back to reference Kiriakopoulos A, Dimitrios T, Dimitrios L: Use of a diathermy system in thyroid surgery. Arch Surg. 2004, 139: 997-1000. 10.1001/archsurg.139.9.997.CrossRefPubMed Kiriakopoulos A, Dimitrios T, Dimitrios L: Use of a diathermy system in thyroid surgery. Arch Surg. 2004, 139: 997-1000. 10.1001/archsurg.139.9.997.CrossRefPubMed
5.
go back to reference Parker DJ, Krupa K, Esler R, Vujovic P, Bennett IC: Use of the harmonic scalpel in thyroidectomy. ANZ J Surg. 2009, 79: 476-480. 10.1111/j.1445-2197.2009.04949.x.CrossRefPubMed Parker DJ, Krupa K, Esler R, Vujovic P, Bennett IC: Use of the harmonic scalpel in thyroidectomy. ANZ J Surg. 2009, 79: 476-480. 10.1111/j.1445-2197.2009.04949.x.CrossRefPubMed
6.
go back to reference Prgomet D, Janjanin S, Bilić M, Prstacić R, Kovac L, Rudes M, Katić V: A prospective observational study of 363 cases operated with three different harmonic scalpels. Eur Arch Otorhinolaryngol. 2009 Dec, 266: 1965-1970. 10.1007/s00405-009-0954-3.CrossRefPubMed Prgomet D, Janjanin S, Bilić M, Prstacić R, Kovac L, Rudes M, Katić V: A prospective observational study of 363 cases operated with three different harmonic scalpels. Eur Arch Otorhinolaryngol. 2009 Dec, 266: 1965-1970. 10.1007/s00405-009-0954-3.CrossRefPubMed
7.
go back to reference Foreman E, Aspinall S, Bliss RD, Lennard TW: The use of the harmonic scalpel in thyroidectomy: 'beyond the learning curve'. Ann R Coll Surg Engl. 2009, 91: 214-216. 10.1308/003588409X391811.PubMedCentralCrossRefPubMed Foreman E, Aspinall S, Bliss RD, Lennard TW: The use of the harmonic scalpel in thyroidectomy: 'beyond the learning curve'. Ann R Coll Surg Engl. 2009, 91: 214-216. 10.1308/003588409X391811.PubMedCentralCrossRefPubMed
8.
go back to reference Sebag F, Fortanier C, Ippolito G, Lagier A, Auquier P, Henry JF: Harmonic scalpel in multinodular goiter surgery: impact on surgery and cost analysis. J Laparoendosc Adv Surg Tech A. 2009, 19: 171-174. 10.1089/lap.2008.0043.CrossRefPubMed Sebag F, Fortanier C, Ippolito G, Lagier A, Auquier P, Henry JF: Harmonic scalpel in multinodular goiter surgery: impact on surgery and cost analysis. J Laparoendosc Adv Surg Tech A. 2009, 19: 171-174. 10.1089/lap.2008.0043.CrossRefPubMed
9.
go back to reference Proczko-Markuszewska M, Kobiela J, Stefaniak T, Lachiński AJ, Sledziński Z: Postoperative PTH measurement as a predictor of hypocalcaemia after thyroidectomy. Acta Chir Belg. 2010, 110: 40-44.PubMed Proczko-Markuszewska M, Kobiela J, Stefaniak T, Lachiński AJ, Sledziński Z: Postoperative PTH measurement as a predictor of hypocalcaemia after thyroidectomy. Acta Chir Belg. 2010, 110: 40-44.PubMed
10.
go back to reference Vaiman M, Nagibin A, Olevson J: Complications in primary and completed thyroidectomy. Surg Today. 2010, 40: 114-118. 10.1007/s00595-008-4027-9.CrossRefPubMed Vaiman M, Nagibin A, Olevson J: Complications in primary and completed thyroidectomy. Surg Today. 2010, 40: 114-118. 10.1007/s00595-008-4027-9.CrossRefPubMed
11.
go back to reference Youssef T, Gaballah G, Abd-Elaal E, El-Dosoky E: Assessment of risk factors of incidental parathyroidectomy during thyroid surgery: a prospective study. Int J Surg. 2010, 8: 207-211. 10.1016/j.ijsu.2009.12.008.CrossRefPubMed Youssef T, Gaballah G, Abd-Elaal E, El-Dosoky E: Assessment of risk factors of incidental parathyroidectomy during thyroid surgery: a prospective study. Int J Surg. 2010, 8: 207-211. 10.1016/j.ijsu.2009.12.008.CrossRefPubMed
12.
go back to reference Chisholm EJ, Kulinskaya E, Tolley NS: Systematic review and meta-analysis of the adverse effects of thyroidectomy combined with central neck dissection as compared with thyroidectomy alone. Laryngoscope. 2009, 119: 1135-1139. 10.1002/lary.20236.CrossRefPubMed Chisholm EJ, Kulinskaya E, Tolley NS: Systematic review and meta-analysis of the adverse effects of thyroidectomy combined with central neck dissection as compared with thyroidectomy alone. Laryngoscope. 2009, 119: 1135-1139. 10.1002/lary.20236.CrossRefPubMed
13.
go back to reference Jeannon JP, Orabi AA, Bruch GA, Abdalsalam HA, Simo R: Diagnosis of recurrent laryngeal nerve palsy after thyroidectomy: a systematic review. Int J Clin Pract. 2009, 63: 624-629. 10.1111/j.1742-1241.2008.01875.x.CrossRefPubMed Jeannon JP, Orabi AA, Bruch GA, Abdalsalam HA, Simo R: Diagnosis of recurrent laryngeal nerve palsy after thyroidectomy: a systematic review. Int J Clin Pract. 2009, 63: 624-629. 10.1111/j.1742-1241.2008.01875.x.CrossRefPubMed
14.
go back to reference Donnellan KA, Pitman KT, Cannon CR, Replogle WH, Simmons JD: Intraoperative laryngeal nerve monitoring during thyroidectomy. Arch Otolaryngol Head Neck Surg. 2009, 135: 1196-1198. 10.1001/archoto.2009.167.CrossRefPubMed Donnellan KA, Pitman KT, Cannon CR, Replogle WH, Simmons JD: Intraoperative laryngeal nerve monitoring during thyroidectomy. Arch Otolaryngol Head Neck Surg. 2009, 135: 1196-1198. 10.1001/archoto.2009.167.CrossRefPubMed
15.
go back to reference Dralle H, Sekulla C, Lorenz K, Brauckhoff M, Machens A: Intraoperative monitoring of the recurrent laryngeal nerve in thyroid surgery. World J Surg. 2008, 32: 1358-1366. 10.1007/s00268-008-9483-2.CrossRefPubMed Dralle H, Sekulla C, Lorenz K, Brauckhoff M, Machens A: Intraoperative monitoring of the recurrent laryngeal nerve in thyroid surgery. World J Surg. 2008, 32: 1358-1366. 10.1007/s00268-008-9483-2.CrossRefPubMed
16.
go back to reference Grodski S, Serpell J: Evidence for the role of perioperative PTH measurement after total thyroidectomy as a predictor of hypocalcemia. World J Surg. 2008, 32: 1367-1373. 10.1007/s00268-008-9545-5.CrossRefPubMed Grodski S, Serpell J: Evidence for the role of perioperative PTH measurement after total thyroidectomy as a predictor of hypocalcemia. World J Surg. 2008, 32: 1367-1373. 10.1007/s00268-008-9545-5.CrossRefPubMed
17.
go back to reference Sabour S, Manders E, Steward DL: The role of rapid PACU parathyroid hormone in reducing post-thyroidectomy hypocalcemia. Otolaryngol Head Neck Surg. 2009, 141: 727-729. 10.1016/j.otohns.2009.08.026.CrossRefPubMed Sabour S, Manders E, Steward DL: The role of rapid PACU parathyroid hormone in reducing post-thyroidectomy hypocalcemia. Otolaryngol Head Neck Surg. 2009, 141: 727-729. 10.1016/j.otohns.2009.08.026.CrossRefPubMed
18.
go back to reference Halsted WS: The operative story of goitre: The author’s operation. (Johns Hopkins Hospital Reports). 1920, Johns Hopkins Press, Baltimore, MD Halsted WS: The operative story of goitre: The author’s operation. (Johns Hopkins Hospital Reports). 1920, Johns Hopkins Press, Baltimore, MD
19.
go back to reference Rouwen KW, Fest J: The best surgical approach for treating multinodular goiter. A systematic review. Erasmus J Med. 2011, l 2: 24-29. Rouwen KW, Fest J: The best surgical approach for treating multinodular goiter. A systematic review. Erasmus J Med. 2011, l 2: 24-29.
20.
go back to reference Leonard DS, Timon C: Prospective trial of the ultrasonic dissector in thyroid surgery. Head Neck. 2008, 30: 904-908. 10.1002/hed.20805.CrossRefPubMed Leonard DS, Timon C: Prospective trial of the ultrasonic dissector in thyroid surgery. Head Neck. 2008, 30: 904-908. 10.1002/hed.20805.CrossRefPubMed
21.
go back to reference D’Ajello F, Cirocchi R, Docimo G, Catania A, Ardito G, Rosato L, Avenia N: Thyroidectomy with ultrasonic dissector: a multicentric experience. G Chir. 2010, 31: 289-292.PubMed D’Ajello F, Cirocchi R, Docimo G, Catania A, Ardito G, Rosato L, Avenia N: Thyroidectomy with ultrasonic dissector: a multicentric experience. G Chir. 2010, 31: 289-292.PubMed
22.
go back to reference Cirocchi R, D’Ajello F, Trastulli S, Santoro A, Di Rocco G, Vendettuoli D, Rondelli F, Giannotti D, Sanguinetti A, Minelli L, Redler A, Basoli A, Avenia N: Meta-analysis of thyroidectomy with ultrasonic dissector versus conventional clamp and tie. World J Surg Oncol. 2010, 23: 112-CrossRef Cirocchi R, D’Ajello F, Trastulli S, Santoro A, Di Rocco G, Vendettuoli D, Rondelli F, Giannotti D, Sanguinetti A, Minelli L, Redler A, Basoli A, Avenia N: Meta-analysis of thyroidectomy with ultrasonic dissector versus conventional clamp and tie. World J Surg Oncol. 2010, 23: 112-CrossRef
23.
go back to reference Defechereux T, Rinken F, Maweja S, Hamoir E, Meurisse M: Evaluation of the ultrasonic dissector in thyroid surgery. A prospective randomised study. Acta Chir Belg. 2003, 103: 274-277.PubMed Defechereux T, Rinken F, Maweja S, Hamoir E, Meurisse M: Evaluation of the ultrasonic dissector in thyroid surgery. A prospective randomised study. Acta Chir Belg. 2003, 103: 274-277.PubMed
Metadata
Title
Total thyroidectomy with ultrasonic dissector for cancer: multicentric experience
Authors
Roberto Cirocchi
Carlo Boselli
Salvatore Guarino
Alessandro Sanguinetti
Stefano Trastulli
Jacopo Desiderio
Alberto Santoro
Fabio Rondelli
Giovanni Conzo
Domenico Parmeggiani
Giuseppe Noya
Giorgio De Toma
Nicola Avenia
Publication date
01-12-2012
Publisher
BioMed Central
Published in
World Journal of Surgical Oncology / Issue 1/2012
Electronic ISSN: 1477-7819
DOI
https://doi.org/10.1186/1477-7819-10-70

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