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World Journal of Surgery

Published in:

01-07-2008

Intraoperative Monitoring of the Recurrent Laryngeal Nerve in Thyroid Surgery

Authors: H. Dralle, C. Sekulla, K. Lorenz, M. Brauckhoff, A. Machens, the German IONM Study Group

Published in: World Journal of Surgery | Issue 7/2008

Abstract

Background

Recurrent laryngeal nerve (RLN) palsy ranks among the leading reasons for medicolegal litigation of surgeons because of its attendant reduction in quality of life. As a risk minimization tool, intraoperative nerve monitoring (IONM) has been introduced to verify RLN function integrity intraoperatively. Nevertheless, a systematic evidence-based assessment of this novel health technology has not been performed.

Methods

The present study was based on a systematic appraisal of the literature using evidence-based criteria.

Results

Recurrent laryngeal nerve palsy rates (RLNPR) varied widely after thyroid surgery, ranging from 0%–7.1% for transient RLN palsy to 0%–11% for permanent RLN palsy. These rates did not differ much from those reported for visual nerve identification without the use of IONM. Six studies with more than 100 nerves at risk (NAR) each evaluated RLNPR by contrasting IONM with visual nerve identification only. Recuurent laryngeal nerve palsy rates tended to be lower with IONM than without it, but this difference was not statistically significant. Six additional studies compared IONM findings with their corresponding postoperative laryngoscopic results. Those studies revealed high negative predictive values (NPV; 92%–100%), but relatively low and variable positive predictive values (PPV; 10%–90%) for IONM, limiting its utility for intraoperative RLN management.

Conclusions

Apart from navigating the surgeon through challenging anatomies, IONM may lend itself as a routine adjunct to the gold standard of visual nerve identification. To further reduce the number of false negative IONM signals, the causes underlying its relatively low PPV require additional clarification.

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Title: Intraoperative Monitoring of the Recurrent Laryngeal Nerve in Thyroid Surgery
Authors: H. Dralle
C. Sekulla
K. Lorenz
M. Brauckhoff
A. Machens
the German IONM Study Group
Publication date: 01-07-2008
Publisher: Springer-Verlag
Published in: World Journal of Surgery / Issue 7/2008
Print ISSN: 0364-2313
Electronic ISSN: 1432-2323
DOI: https://doi.org/10.1007/s00268-008-9483-2

At a glance: The STEP trials

Springer Medicine

Intraoperative Monitoring of the Recurrent Laryngeal Nerve in Thyroid Surgery

Abstract

Background

Methods

Results

Conclusions

At a glance: The STEP trials

Springer Medicine

Abstract

Background

Methods

Results

Conclusions

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