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World Journal of Surgical Oncology

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Open Access 01-12-2012 | Case report

Cutaneous leiomyosarcoma arising in a smallpox scar

Authors: Robert A Pol, Hilde Dannenberg, Jan-Lukas Robertus, Robert J van Ginkel

Published in: World Journal of Surgical Oncology | Issue 1/2012

Abstract

Background

Cutaneous leiomyosarcoma (CLM) is a very rare smooth muscle tumour that accounts for about 2–3% of all superficial soft tissue sarcomas. Although the development of various malignancies in scar tissue is well known, we report the first case of a CLM developing in a small pox scar.

Case presentation

A 66-year-old man presented with a painless, slow-growing lump in a small pox scar on his left shoulder. Histological biopsies showed the lesion to be a primary, well-differentiated cutaneous leiomyosarcoma. A CT scan of the thorax was conducted, which showed no signs of metastases. The complete lesion was then surgically excised, and histopathological examination revealed a radically excised cutaneous type leiomyosarcoma After 13 months’ review the patient was doing well with no evidence of tumour recurrence.

Conclusions

This is the first report of a CLM arising in a small pox scar. Although the extended time interval between scarring and malignant changes makes it difficult to advise strict follow-up for patients with small pox scars, one should be aware that atypical changes and/or symptoms occurring in a small pox scar could potentially mean malignant transformation.

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Title: Cutaneous leiomyosarcoma arising in a smallpox scar
Authors: Robert A Pol
Hilde Dannenberg
Jan-Lukas Robertus
Robert J van Ginkel
Publication date: 01-12-2012
Publisher: BioMed Central
Published in: World Journal of Surgical Oncology / Issue 1/2012
Electronic ISSN: 1477-7819
DOI: https://doi.org/10.1186/1477-7819-10-148

Keynote webinar | Spotlight on sleep in brain health

Springer Medicine

Cutaneous leiomyosarcoma arising in a smallpox scar

Abstract

Background

Case presentation

Conclusions

Keynote webinar | Spotlight on sleep in brain health

Springer Medicine

Abstract

Background

Case presentation

Conclusions

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