Published in:
Open Access
01-08-2013 | Poster presentation
Do allergic dogs exhibit features of a severe steroid-resistant allergic airway phenotype?
Authors:
Edward G Barrett, Christopher M Royer, Karin Rudolph, Phillip J Kuehl
Published in:
Journal of Inflammation
|
Special Issue 1/2013
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Excerpt
Most asthmatic patients respond favorably to corticosteroid therapy, however, a subpopulation of patients (5-10%) display persistent immune activation and airway inflammation, despite high doses of oral/inhaled corticosteroids. The development of more predictive animal models that incorporate the severe steroid-resistant phenotype are needed to better define translational biomarkers and therapeutic targets for this patient population. …