Skip to main content
Top
Published in: BMC Musculoskeletal Disorders 1/2012

Open Access 01-12-2012 | Research article

Prevalence of vertebral fractures in women and men in the population-based Tromsø Study

Authors: Svanhild Waterloo, Luai A Ahmed, Jacqueline R Center, John A Eisman, Bente Morseth, Nguyen D Nguyen, Tuan Nguyen, Anne J Sogaard, Nina Emaus

Published in: BMC Musculoskeletal Disorders | Issue 1/2012

Login to get access

Abstract

Background

Osteoporotic vertebral fractures are, as the hip fractures, associated with increased morbidity and mortality. Norway has one of the highest reported incidences of hip fractures in the world. Because of methodological challenges, vertebral fractures are not extensively studied. The aim of this population based study was to describe, for the first time, the age- and sex specific occurrence of osteoporotic vertebral fractures in Norway.

Methods

Data was collected in the Tromso Study, 2007/8 survey. By the use of dual x-ray absorptiometry (GE Lunar Prodigy) vertebral fracture assessments were performed in 2887 women and men aged from 38 to 87 years, in addition to measurements of bone mineral density at the femoral sites. Information on lifestyle was collected through questionnaires. Comparisons between fractures and non-fractures were done sex stratified, by univariate analyses, adjusting for age when relevant.

Results

The prevalence of vertebral fractures varied from about 3% in the age group below 60 to about 19% in the 70+ group in women, and from 7.5% to about 20% in men, with an overall prevalence of 11.8% in women and 13.8% in men (p = 0.07). Among those with fractures, only one fracture was the most common; two and more fractures were present in approximately 30% of the cases. Fractures were seen from the fourth lumbar to the fifth thoracic vertebrae, most common between first lumbar and sixth thoracic vertebrae. The most common type of fracture was the wedge type in both sexes. Bone mineral density at the hip differed significantly according to type of fracture, being highest in those with wedge fractures and lowest in those with compression fractures.

Conclusions

The prevalence of vertebral fractures increased by age in women and men, but the overall prevalence was lower than expected, considering the high prevalence of hip and forearm fractures in Norway. In both sexes, the wedge type was the fracture type most frequently observed and most common in the thoracic region.
Appendix
Available only for authorised users
Literature
1.
go back to reference Compston J: Osteoporosis: social and economic impact. Radiol Clin North Am. 2010, 48 (3): 477-482. 10.1016/j.rcl.2010.02.010.CrossRefPubMed Compston J: Osteoporosis: social and economic impact. Radiol Clin North Am. 2010, 48 (3): 477-482. 10.1016/j.rcl.2010.02.010.CrossRefPubMed
2.
go back to reference Bliuc D, Nguyen ND, Milch VE, Nguyen TV, Eisman JA, Center JR: Mortality risk associated with low-trauma osteoporotic fracture and subsequent fracture in men and women. JAMA. 2009, 301 (5): 513-521. 10.1001/jama.2009.50.CrossRefPubMed Bliuc D, Nguyen ND, Milch VE, Nguyen TV, Eisman JA, Center JR: Mortality risk associated with low-trauma osteoporotic fracture and subsequent fracture in men and women. JAMA. 2009, 301 (5): 513-521. 10.1001/jama.2009.50.CrossRefPubMed
3.
go back to reference Harvey N, Dennison E, Cooper C: Osteoporosis: impact on health and economics. Nat Rev Rheumatol. 2010, 6 (2): 99-105. 10.1038/nrrheum.2009.260.CrossRefPubMed Harvey N, Dennison E, Cooper C: Osteoporosis: impact on health and economics. Nat Rev Rheumatol. 2010, 6 (2): 99-105. 10.1038/nrrheum.2009.260.CrossRefPubMed
4.
go back to reference Johnell O, Kanis J: An estimate of the worldwide prevalence and disability associated with osteoporotic fractures. Osteoporos Int. 2006, 17 (12): 1726-1733. 10.1007/s00198-006-0172-4.CrossRefPubMed Johnell O, Kanis J: An estimate of the worldwide prevalence and disability associated with osteoporotic fractures. Osteoporos Int. 2006, 17 (12): 1726-1733. 10.1007/s00198-006-0172-4.CrossRefPubMed
5.
go back to reference Tsai KS, Twu SJ, Chieng PU, Yang RS, Lee TK, the Geriatric Study Group ROC: Prevalence of vertebral fractures in Chinese men and women in urban Taiwanese communities. Calcif Tissue Int. 1996, 59 (4): 249-253. 10.1007/s002239900118.CrossRefPubMed Tsai KS, Twu SJ, Chieng PU, Yang RS, Lee TK, the Geriatric Study Group ROC: Prevalence of vertebral fractures in Chinese men and women in urban Taiwanese communities. Calcif Tissue Int. 1996, 59 (4): 249-253. 10.1007/s002239900118.CrossRefPubMed
6.
go back to reference Francis R, Aspray T, Hide G, Sutcliffe A, Wilkinson P: Back pain in osteoporotic vertebral fractures. Osteoporos Int. 2008, 19 (7): 895-903. 10.1007/s00198-007-0530-x.CrossRefPubMed Francis R, Aspray T, Hide G, Sutcliffe A, Wilkinson P: Back pain in osteoporotic vertebral fractures. Osteoporos Int. 2008, 19 (7): 895-903. 10.1007/s00198-007-0530-x.CrossRefPubMed
7.
go back to reference Chen P, Krege JH, Adachi JD, Prior JC, Tenenhouse A, Brown JP, Papadimitropoulos E, Kreiger N, Olszynski WP, Josse RG: Vertebral fracture status and the World Health Organization risk factors for predicting osteoporotic fracture risk. J Bone Miner Res. 2009, 24 (3): 495-502. 10.1359/jbmr.081103.CrossRefPubMed Chen P, Krege JH, Adachi JD, Prior JC, Tenenhouse A, Brown JP, Papadimitropoulos E, Kreiger N, Olszynski WP, Josse RG: Vertebral fracture status and the World Health Organization risk factors for predicting osteoporotic fracture risk. J Bone Miner Res. 2009, 24 (3): 495-502. 10.1359/jbmr.081103.CrossRefPubMed
8.
go back to reference Cooper C: Epidemiology and public health impact of osteoporosis. Baillieres Clin Rheumatol. 1993, 7 (3): 459-477. 10.1016/S0950-3579(05)80073-1.CrossRefPubMed Cooper C: Epidemiology and public health impact of osteoporosis. Baillieres Clin Rheumatol. 1993, 7 (3): 459-477. 10.1016/S0950-3579(05)80073-1.CrossRefPubMed
9.
go back to reference Roux C, Fechtenbaum J, Kolta S, Briot K, Girard M: Mild prevalent and incident vertebral fractures are risk factors for new fractures. Osteoporos Int. 2007, 18 (12): 1617-1624. 10.1007/s00198-007-0413-1.CrossRefPubMed Roux C, Fechtenbaum J, Kolta S, Briot K, Girard M: Mild prevalent and incident vertebral fractures are risk factors for new fractures. Osteoporos Int. 2007, 18 (12): 1617-1624. 10.1007/s00198-007-0413-1.CrossRefPubMed
10.
go back to reference Silverman S: Quality-of-life issues in osteoporosis. Curr Rheumatol Rep. 2005, 7 (1): 39-45. 10.1007/s11926-005-0007-x.CrossRefPubMed Silverman S: Quality-of-life issues in osteoporosis. Curr Rheumatol Rep. 2005, 7 (1): 39-45. 10.1007/s11926-005-0007-x.CrossRefPubMed
11.
go back to reference Kim N, Rowe BH, Raymond G, Jen H, Colman I, Jackson SA, Siminoski KG, Chahal AM, Folk D, Majumdar SR: Underreporting of vertebral fractures on routine chest radiography. Am J Roentgenol. 2004, 182 (2): 297-300.CrossRef Kim N, Rowe BH, Raymond G, Jen H, Colman I, Jackson SA, Siminoski KG, Chahal AM, Folk D, Majumdar SR: Underreporting of vertebral fractures on routine chest radiography. Am J Roentgenol. 2004, 182 (2): 297-300.CrossRef
12.
go back to reference Kanis JA, Johnell O, Oden A, Borgstrom F, Zethraeus N, Laet C, Jonsson B: The risk and burden of vertebral fractures in Sweden. Osteoporos Int. 2004, 15 (1): 20-26. 10.1007/s00198-003-1463-7.CrossRefPubMed Kanis JA, Johnell O, Oden A, Borgstrom F, Zethraeus N, Laet C, Jonsson B: The risk and burden of vertebral fractures in Sweden. Osteoporos Int. 2004, 15 (1): 20-26. 10.1007/s00198-003-1463-7.CrossRefPubMed
13.
go back to reference Center JR, Nguyen TV, Schneider D, Sambrook PN, Eisman JA: Mortality after all major types of osteoporotic fracture in men and women: an observational study. The Lancet. 1999, 353 (9156): 878-882. 10.1016/S0140-6736(98)09075-8.CrossRef Center JR, Nguyen TV, Schneider D, Sambrook PN, Eisman JA: Mortality after all major types of osteoporotic fracture in men and women: an observational study. The Lancet. 1999, 353 (9156): 878-882. 10.1016/S0140-6736(98)09075-8.CrossRef
14.
go back to reference Iacovino J: Mortality outcomes after osteoporotic fractures in men and women. J Insur Med. 2001, 33 (4): 316-320.PubMed Iacovino J: Mortality outcomes after osteoporotic fractures in men and women. J Insur Med. 2001, 33 (4): 316-320.PubMed
15.
go back to reference Johnell O, Kanis JA, Odén A, Sernbo I, Redlund-Johnell I, Petterson C, Laet C, Jönsson B: Mortality after osteoporotic fractures. Osteoporos Int. 2004, 15 (1): 38-42. 10.1007/s00198-003-1490-4.CrossRefPubMed Johnell O, Kanis JA, Odén A, Sernbo I, Redlund-Johnell I, Petterson C, Laet C, Jönsson B: Mortality after osteoporotic fractures. Osteoporos Int. 2004, 15 (1): 38-42. 10.1007/s00198-003-1490-4.CrossRefPubMed
16.
go back to reference Lindsay R, Silverman SL, Cooper C, Hanley DA, Barton I, Broy SB, Licata A, Benhamou L, Geusens P, Flowers K: Risk of new vertebral fracture in the year following a fracture. JAMA. 2001, 285 (3): 320-323. 10.1001/jama.285.3.320.CrossRefPubMed Lindsay R, Silverman SL, Cooper C, Hanley DA, Barton I, Broy SB, Licata A, Benhamou L, Geusens P, Flowers K: Risk of new vertebral fracture in the year following a fracture. JAMA. 2001, 285 (3): 320-323. 10.1001/jama.285.3.320.CrossRefPubMed
17.
go back to reference Naves M, Díaz-López JB, Gómez C, Rodríguez-Rebollar A, Rodríguez-García M, Cannata-Andía JB: The effect of vertebral fracture as a risk factor for osteoporotic fracture and mortality in a Spanish population. Osteoporos Int. 2003, 14 (6): 520-524. 10.1007/s00198-003-1405-4.CrossRefPubMed Naves M, Díaz-López JB, Gómez C, Rodríguez-Rebollar A, Rodríguez-García M, Cannata-Andía JB: The effect of vertebral fracture as a risk factor for osteoporotic fracture and mortality in a Spanish population. Osteoporos Int. 2003, 14 (6): 520-524. 10.1007/s00198-003-1405-4.CrossRefPubMed
18.
go back to reference Briggs A, Greig A, Wark J: The vertebral fracture cascade in osteoporosis: a review of aetiopathogenesis. Osteoporos Int. 2007, 18 (5): 575-584. 10.1007/s00198-006-0304-x.CrossRefPubMed Briggs A, Greig A, Wark J: The vertebral fracture cascade in osteoporosis: a review of aetiopathogenesis. Osteoporos Int. 2007, 18 (5): 575-584. 10.1007/s00198-006-0304-x.CrossRefPubMed
19.
go back to reference Melton L: Vertebral fractures predict subsequent fractures. Osteoporos Int. 1999, 10: 214-221. 10.1007/s001980050218.CrossRefPubMed Melton L: Vertebral fractures predict subsequent fractures. Osteoporos Int. 1999, 10: 214-221. 10.1007/s001980050218.CrossRefPubMed
20.
go back to reference Middleton E, Gardiner E, Steel S: Which women should be selected for vertebral fracture assessment? Comparing different methods of targeting VFA. Calcif Tissue Int. 2009, 85 (3): 203-210. 10.1007/s00223-009-9268-0.CrossRefPubMed Middleton E, Gardiner E, Steel S: Which women should be selected for vertebral fracture assessment? Comparing different methods of targeting VFA. Calcif Tissue Int. 2009, 85 (3): 203-210. 10.1007/s00223-009-9268-0.CrossRefPubMed
21.
go back to reference Puisto V, Heliövaara M, Impivaara O, Jalanko T, Kröger H, Knekt P, Aromaa A, Rissanen H, Helenius I: Severity of vertebral fracture and risk of hip fracture: a nested case-control study. Osteoporos Int. 2011, 22 (1): 63-68. 10.1007/s00198-010-1195-4.CrossRefPubMed Puisto V, Heliövaara M, Impivaara O, Jalanko T, Kröger H, Knekt P, Aromaa A, Rissanen H, Helenius I: Severity of vertebral fracture and risk of hip fracture: a nested case-control study. Osteoporos Int. 2011, 22 (1): 63-68. 10.1007/s00198-010-1195-4.CrossRefPubMed
22.
go back to reference Burger H, Van Daele PLA, Grashuis K, Hofman A, Grobbee DE, Schütte HE, Birkenhäger JC, Pols HAP: Vertebral deformities and functional impairment in men and women. J Bone Miner Res. 1997, 12 (1): 152-157. 10.1359/jbmr.1997.12.1.152.CrossRefPubMed Burger H, Van Daele PLA, Grashuis K, Hofman A, Grobbee DE, Schütte HE, Birkenhäger JC, Pols HAP: Vertebral deformities and functional impairment in men and women. J Bone Miner Res. 1997, 12 (1): 152-157. 10.1359/jbmr.1997.12.1.152.CrossRefPubMed
23.
go back to reference Melton L, Wenger D, Atkinson E, Achenbach S, Berquist T, Riggs B, Jiang G, Eastell R: Influence of baseline deformity definition on subsequent vertebral fracture risk in postmenopausal women. Osteoporos Int. 2006, 17 (7): 978-985. 10.1007/s00198-006-0106-1.CrossRefPubMed Melton L, Wenger D, Atkinson E, Achenbach S, Berquist T, Riggs B, Jiang G, Eastell R: Influence of baseline deformity definition on subsequent vertebral fracture risk in postmenopausal women. Osteoporos Int. 2006, 17 (7): 978-985. 10.1007/s00198-006-0106-1.CrossRefPubMed
24.
go back to reference Pasco J, Henry M, Korn S, Nicholson G, Kotowicz M: Morphometric vertebral fractures of the lower thoracic and lumbar spine, physical function and quality of life in men. Osteoporos Int. 2009, 20 (5): 787-792. 10.1007/s00198-008-0744-6.CrossRefPubMed Pasco J, Henry M, Korn S, Nicholson G, Kotowicz M: Morphometric vertebral fractures of the lower thoracic and lumbar spine, physical function and quality of life in men. Osteoporos Int. 2009, 20 (5): 787-792. 10.1007/s00198-008-0744-6.CrossRefPubMed
25.
go back to reference Ho-Pham LT, Nguyen ND, Vu BQ, Pham HN, Nguyen TV: Prevalence and risk factors of radiographic vertebral fracture in postmenopausal Vietnamese women. Bone. 2009, 45 (2): 213-217. 10.1016/j.bone.2009.04.199.CrossRefPubMed Ho-Pham LT, Nguyen ND, Vu BQ, Pham HN, Nguyen TV: Prevalence and risk factors of radiographic vertebral fracture in postmenopausal Vietnamese women. Bone. 2009, 45 (2): 213-217. 10.1016/j.bone.2009.04.199.CrossRefPubMed
26.
go back to reference Clark P, Cons-Molina F, Deleze M, Talavera J, Palermo L, Cummings S: The prevalence of radiographic vertebral fractures in Mexican men. Osteoporos Int. 2010, 21 (9): 1523-1528. 10.1007/s00198-009-1109-5.CrossRefPubMed Clark P, Cons-Molina F, Deleze M, Talavera J, Palermo L, Cummings S: The prevalence of radiographic vertebral fractures in Mexican men. Osteoporos Int. 2010, 21 (9): 1523-1528. 10.1007/s00198-009-1109-5.CrossRefPubMed
27.
go back to reference van Schoor N, Ewing S, O'Neill T, Lunt M, Smit J, Lips P: Impact of prevalent and incident vertebral fractures on utility: results from a patient-based and a population-based sample. Qual Life Res. 2008, 17 (1): 159-167. 10.1007/s11136-007-9287-0.CrossRefPubMed van Schoor N, Ewing S, O'Neill T, Lunt M, Smit J, Lips P: Impact of prevalent and incident vertebral fractures on utility: results from a patient-based and a population-based sample. Qual Life Res. 2008, 17 (1): 159-167. 10.1007/s11136-007-9287-0.CrossRefPubMed
28.
go back to reference Grazio S: Prevalence of vertebral fractures in an urban population in Croatia aged 50 years and older. Wien Klin Wochenschr. 2005, 117: (1-2):42-47.CrossRef Grazio S: Prevalence of vertebral fractures in an urban population in Croatia aged 50 years and older. Wien Klin Wochenschr. 2005, 117: (1-2):42-47.CrossRef
29.
go back to reference Cauley JA, Palermo L, Vogt M, Ensrud KE, Ewing S, Hochberg M, Nevitt MC, Black DM: Prevalent vertebral fractures in black women and white women. J Bone Miner Res. 2008, 23 (9): 1458-1467. 10.1359/jbmr.080411.CrossRefPubMedPubMedCentral Cauley JA, Palermo L, Vogt M, Ensrud KE, Ewing S, Hochberg M, Nevitt MC, Black DM: Prevalent vertebral fractures in black women and white women. J Bone Miner Res. 2008, 23 (9): 1458-1467. 10.1359/jbmr.080411.CrossRefPubMedPubMedCentral
30.
go back to reference Jones G: Prevalent vertebral deformities: relationship to bone mineral density and spinal osteophytosis in elderly men and women. Osteoporos Int. 1996, 6 (3): 233-239. 10.1007/BF01622740.CrossRefPubMed Jones G: Prevalent vertebral deformities: relationship to bone mineral density and spinal osteophytosis in elderly men and women. Osteoporos Int. 1996, 6 (3): 233-239. 10.1007/BF01622740.CrossRefPubMed
31.
go back to reference Gallacher S, Gallagher A, McQuillian C, Mitchell P, Dixon T: The prevalence of vertebral fracture amongst patients presenting with non-vertebral fractures. Osteoporos Int. 2007, 18 (2): 185-192. 10.1007/s00198-006-0211-1.CrossRefPubMed Gallacher S, Gallagher A, McQuillian C, Mitchell P, Dixon T: The prevalence of vertebral fracture amongst patients presenting with non-vertebral fractures. Osteoporos Int. 2007, 18 (2): 185-192. 10.1007/s00198-006-0211-1.CrossRefPubMed
32.
go back to reference Vokes TJ, Gillen DL, Pham AT, Lovett JM: Risk factors for prevalent vertebral fractures in black and white female densitometry patients. J Clin Densitom. 2007, 10 (1): 1-9. 10.1016/j.jocd.2006.11.002.CrossRefPubMed Vokes TJ, Gillen DL, Pham AT, Lovett JM: Risk factors for prevalent vertebral fractures in black and white female densitometry patients. J Clin Densitom. 2007, 10 (1): 1-9. 10.1016/j.jocd.2006.11.002.CrossRefPubMed
33.
go back to reference Lansdown D, Bennet B, Thiel S, Ahmed O, Dixon L, Vokes T: Prevalence of vertebral fractures on chest radiographs of elderly African American and Caucasian women. Osteoporos Int. 2011, 22 (8): 2365-2371. 10.1007/s00198-010-1452-6.CrossRefPubMed Lansdown D, Bennet B, Thiel S, Ahmed O, Dixon L, Vokes T: Prevalence of vertebral fractures on chest radiographs of elderly African American and Caucasian women. Osteoporos Int. 2011, 22 (8): 2365-2371. 10.1007/s00198-010-1452-6.CrossRefPubMed
34.
go back to reference Rostom S, Allali F, Bennani L, Abouqal R, Hajjaj-Hassouni N: The prevalence of vertebral fractures and health-related quality of life in postmenopausal women. Rheumatol Intl. 2011, (DOI 10.1007/s00296-010-1734-5) Rostom S, Allali F, Bennani L, Abouqal R, Hajjaj-Hassouni N: The prevalence of vertebral fractures and health-related quality of life in postmenopausal women. Rheumatol Intl. 2011, (DOI 10.1007/s00296-010-1734-5)
35.
go back to reference Lofthus CM, Osnes EK, Falch JA, Kaastad TS, Kristiansen IS, Nordsletten L, Stensvold I, Meyer HE: Epidemiology of hip fractures in Oslo, Norway. Bone. 2001, 29 (5): 413-418. 10.1016/S8756-3282(01)00603-2.CrossRefPubMed Lofthus CM, Osnes EK, Falch JA, Kaastad TS, Kristiansen IS, Nordsletten L, Stensvold I, Meyer HE: Epidemiology of hip fractures in Oslo, Norway. Bone. 2001, 29 (5): 413-418. 10.1016/S8756-3282(01)00603-2.CrossRefPubMed
36.
go back to reference Lofthus C, Frihagen F, Meyer H, Nordsletten L, Melhuus K, Falch J: Epidemiology of distal forearm fractures in Oslo, Norway. Osteoporos Int. 2008, 19 (6): 781-786. 10.1007/s00198-007-0499-5.CrossRefPubMed Lofthus C, Frihagen F, Meyer H, Nordsletten L, Melhuus K, Falch J: Epidemiology of distal forearm fractures in Oslo, Norway. Osteoporos Int. 2008, 19 (6): 781-786. 10.1007/s00198-007-0499-5.CrossRefPubMed
37.
go back to reference Jacobsen BK, Eggen AE, Mathiesen EB, Wilsgaard T, Njølstad I: Cohort profile: the Tromsø study. Int J Epidemiol. 2011, (DOI 10.1093/ije/dyr049) Jacobsen BK, Eggen AE, Mathiesen EB, Wilsgaard T, Njølstad I: Cohort profile: the Tromsø study. Int J Epidemiol. 2011, (DOI 10.1093/ije/dyr049)
38.
go back to reference Jacobsen BK, Njolstad I, Thune I, Wilsgaard T, Lochen M-L, Schirmer H: Increase in weight in all birth cohorts in a general population: the Tromso study, 1974-1994. Arch Intern Med. 2001, 161 (3): 466-472. 10.1001/archinte.161.3.466.CrossRefPubMed Jacobsen BK, Njolstad I, Thune I, Wilsgaard T, Lochen M-L, Schirmer H: Increase in weight in all birth cohorts in a general population: the Tromso study, 1974-1994. Arch Intern Med. 2001, 161 (3): 466-472. 10.1001/archinte.161.3.466.CrossRefPubMed
39.
go back to reference Diacinti D, Guglielmi G: Vertebral morphometry. Radiol Clin North Am. 2010, 48 (3): 561-575. 10.1016/j.rcl.2010.02.018.CrossRefPubMed Diacinti D, Guglielmi G: Vertebral morphometry. Radiol Clin North Am. 2010, 48 (3): 561-575. 10.1016/j.rcl.2010.02.018.CrossRefPubMed
40.
go back to reference El Maghraoui A, Roux C: DXA scanning in clinical practice. QJM. 2008, 101 (8): 605-617. 10.1093/qjmed/hcn022.CrossRefPubMed El Maghraoui A, Roux C: DXA scanning in clinical practice. QJM. 2008, 101 (8): 605-617. 10.1093/qjmed/hcn022.CrossRefPubMed
41.
go back to reference Grigoryan M, Guermazi A, Roemer F, Delmas P, Genant H: Recognizing and reporting osteoporotic vertebral fractures. Eur Spine J. 2003, 12 (0): S104-S112. 10.1007/s00586-003-0613-0.CrossRefPubMedPubMedCentral Grigoryan M, Guermazi A, Roemer F, Delmas P, Genant H: Recognizing and reporting osteoporotic vertebral fractures. Eur Spine J. 2003, 12 (0): S104-S112. 10.1007/s00586-003-0613-0.CrossRefPubMedPubMedCentral
42.
go back to reference Ensrud KE, Schousboe JT: Vertebral fractures. N Engl J Med. 2011, 364 (17): 1634-1642. 10.1056/NEJMcp1009697.CrossRefPubMed Ensrud KE, Schousboe JT: Vertebral fractures. N Engl J Med. 2011, 364 (17): 1634-1642. 10.1056/NEJMcp1009697.CrossRefPubMed
43.
go back to reference Sanfélix-Genovés J, Reig-Molla B, Sanfélix-Gimeno G, Peiró S, Graells-Ferrer M, Vega-Martínez M, Giner V: The population-based prevalence of osteoporotic vertebral fracture and densitometric osteoporosis in postmenopausal women over 50 in Valencia, Spain (the FRAVO Study). Bone. 2010, 47 (3): 610-616. 10.1016/j.bone.2010.06.015.CrossRefPubMed Sanfélix-Genovés J, Reig-Molla B, Sanfélix-Gimeno G, Peiró S, Graells-Ferrer M, Vega-Martínez M, Giner V: The population-based prevalence of osteoporotic vertebral fracture and densitometric osteoporosis in postmenopausal women over 50 in Valencia, Spain (the FRAVO Study). Bone. 2010, 47 (3): 610-616. 10.1016/j.bone.2010.06.015.CrossRefPubMed
44.
go back to reference Omsland TK, Emaus N, Gjesdal CG, Falch JA, Tell GS, Forsen L, Berntsen GK, Meyer HE: In vivo and in vitro comparison of densitometers in the NOREPOS study. J Clin Densitom. 2008, 11 (2): 276-282. 10.1016/j.jocd.2007.10.001.CrossRefPubMed Omsland TK, Emaus N, Gjesdal CG, Falch JA, Tell GS, Forsen L, Berntsen GK, Meyer HE: In vivo and in vitro comparison of densitometers in the NOREPOS study. J Clin Densitom. 2008, 11 (2): 276-282. 10.1016/j.jocd.2007.10.001.CrossRefPubMed
45.
go back to reference O'Neill TW, Felsenberg D, Varlow J, Cooper C, Kanis JA, Silman AJ: The prevalence of vertebral deformity in European men and women: the European vertebral osteoporosis study. J Bone Miner Res. 1996, 11 (7): 1010-1018.CrossRefPubMed O'Neill TW, Felsenberg D, Varlow J, Cooper C, Kanis JA, Silman AJ: The prevalence of vertebral deformity in European men and women: the European vertebral osteoporosis study. J Bone Miner Res. 1996, 11 (7): 1010-1018.CrossRefPubMed
46.
go back to reference Johnell O, Kanis J: Epidemiology of osteoporotic fractures. Osteoporos Int. 2005, 16 (0): S3-S7. 10.1007/s00198-004-1702-6.CrossRefPubMed Johnell O, Kanis J: Epidemiology of osteoporotic fractures. Osteoporos Int. 2005, 16 (0): S3-S7. 10.1007/s00198-004-1702-6.CrossRefPubMed
47.
go back to reference Emaus N, Olsen L, Ahmed L, Balteskard L, Jacobsen B, Magnus T, Ytterstad B: Hip fractures in a city in Northern Norway over 15 years: time trends, seasonal variation and mortality. Osteoporos Int. 2011, 22 (10): 2603-2610. 10.1007/s00198-010-1485-x.CrossRefPubMedPubMedCentral Emaus N, Olsen L, Ahmed L, Balteskard L, Jacobsen B, Magnus T, Ytterstad B: Hip fractures in a city in Northern Norway over 15 years: time trends, seasonal variation and mortality. Osteoporos Int. 2011, 22 (10): 2603-2610. 10.1007/s00198-010-1485-x.CrossRefPubMedPubMedCentral
48.
go back to reference Cummings SR, Melton LJ: Epidemiology and outcomes of osteoporotic fractures. The Lancet. 2002, 359 (9319): 1761-1767. 10.1016/S0140-6736(02)08657-9.CrossRef Cummings SR, Melton LJ: Epidemiology and outcomes of osteoporotic fractures. The Lancet. 2002, 359 (9319): 1761-1767. 10.1016/S0140-6736(02)08657-9.CrossRef
Metadata
Title
Prevalence of vertebral fractures in women and men in the population-based Tromsø Study
Authors
Svanhild Waterloo
Luai A Ahmed
Jacqueline R Center
John A Eisman
Bente Morseth
Nguyen D Nguyen
Tuan Nguyen
Anne J Sogaard
Nina Emaus
Publication date
01-12-2012
Publisher
BioMed Central
Published in
BMC Musculoskeletal Disorders / Issue 1/2012
Electronic ISSN: 1471-2474
DOI
https://doi.org/10.1186/1471-2474-13-3

Other articles of this Issue 1/2012

BMC Musculoskeletal Disorders 1/2012 Go to the issue