Skip to main content
Top
Published in: BMC Nephrology 1/2014

Open Access 01-12-2014 | Research article

Electronic problem list documentation of chronic kidney disease and quality of care

Authors: Lipika Samal, Jeffrey A Linder, David W Bates, Adam Wright

Published in: BMC Nephrology | Issue 1/2014

Login to get access

Abstract

Background

Chronic kidney disease (CKD) is increasingly common and under-recognized in primary care clinics, leading to low rates of stage-appropriate monitoring and treatment. Our objective was to determine whether electronic problem list documentation of CKD is associated with monitoring and treatment.

Methods

This is a cross-sectional observational study of patients with stage 3 or 4 CKD, defined as two past estimated glomerular filtration rates (eGFR) 15-60 mL/min/1.73 m2 separated by 90 days and collected between 2007-2008. We examined the association of problem list documentation with: 1) serum eGFR monitoring test, 2) urine protein or albumin monitoring test, 3) an angiotensin converting enzyme inhibitor or angiotensin receptor blocker (ACE/ARB) prescription, 4) mean systolic blood pressure (BP), and 5) BP control.

Results

Out of 3,149 patients with stage 3 or 4 CKD, only 16% of patients had CKD documented on the problem list. After adjustment for eGFR, gender, and race/ethnicity and after clustering by physician, problem list documentation of CKD was associated with serum eGFR testing (97% with problem list documentation vs. 94% without problem list documentation, p = 0.02) and urine protein testing (47% with problem list documentation vs. 40% without problem list documentation, p = 0.04). After adjustment, problem list documentation was not associated with ACE/ARB prescription, mean systolic BP, or BP control.

Conclusions

Documentation of CKD on the electronic problem list is rare. Patients with CKD documentation have better stage-appropriate monitoring of the disease, but do not have higher rates of blood pressure treatment or better blood pressure control. Interventions aimed at increasing documentation of CKD on the problem list may improve stage-appropriate monitoring, but may not improve clinical outcomes.
Appendix
Available only for authorised users
Literature
1.
go back to reference Coresh J, Selvin E, Stevens LA, Manzi J, Kusek JW, Eggers P, Van Lente F, Levey AS: Prevalence of chronic kidney disease in the United States. JAMA. 2007, 298 (17): 2038-2047. 10.1001/jama.298.17.2038.CrossRefPubMed Coresh J, Selvin E, Stevens LA, Manzi J, Kusek JW, Eggers P, Van Lente F, Levey AS: Prevalence of chronic kidney disease in the United States. JAMA. 2007, 298 (17): 2038-2047. 10.1001/jama.298.17.2038.CrossRefPubMed
2.
go back to reference Giatras I, Lau J, Levey AS: Effect of angiotensin-converting enzyme inhibitors on the progression of nondiabetic renal disease: a meta-analysis of randomized trials: angiotensin-converting-enzyme inhibition and progressive renal disease study group. Ann Intern Med. 1997, 127 (5): 337-345. 10.7326/0003-4819-127-5-199709010-00001.CrossRefPubMed Giatras I, Lau J, Levey AS: Effect of angiotensin-converting enzyme inhibitors on the progression of nondiabetic renal disease: a meta-analysis of randomized trials: angiotensin-converting-enzyme inhibition and progressive renal disease study group. Ann Intern Med. 1997, 127 (5): 337-345. 10.7326/0003-4819-127-5-199709010-00001.CrossRefPubMed
3.
go back to reference Wright JT, Bakris G, Greene T, Agodoa LY, Appel LJ, Charleston J, Cheek D, Douglas-Baltimore JG, Gassman J, Glassock R, Hebert L, Jamerson K, Lewis J, Phillips RA, Toto RD, Middleton JP, Rostand SG, African American Study of Kidney Disease and Hypertension Study Group: Effect of blood pressure lowering and antihypertensive drug class on progression of hypertensive kidney disease: results from the AASK trial. JAMA. 2002, 288 (19): 2421-2431. 10.1001/jama.288.19.2421.CrossRefPubMed Wright JT, Bakris G, Greene T, Agodoa LY, Appel LJ, Charleston J, Cheek D, Douglas-Baltimore JG, Gassman J, Glassock R, Hebert L, Jamerson K, Lewis J, Phillips RA, Toto RD, Middleton JP, Rostand SG, African American Study of Kidney Disease and Hypertension Study Group: Effect of blood pressure lowering and antihypertensive drug class on progression of hypertensive kidney disease: results from the AASK trial. JAMA. 2002, 288 (19): 2421-2431. 10.1001/jama.288.19.2421.CrossRefPubMed
4.
go back to reference Ruggenenti P, Fassi A, Ilieva AP, Bruno S, Iliev IP, Brusegan V, Rubis N, Gherardi G, Arnoldi F, Ganeva M, Ene-Iordache B, Gaspari F, Perna A, Bossi A, Trevisan R, Dodesini AR, Remuzzi G: Bergamo nephrologic diabetes complications trial (BENEDICT) investigators: preventing microalbuminuria in type 2 diabetes. N Engl J Med. 2004, 351 (19): 1941-1951. 10.1056/NEJMoa042167.CrossRefPubMed Ruggenenti P, Fassi A, Ilieva AP, Bruno S, Iliev IP, Brusegan V, Rubis N, Gherardi G, Arnoldi F, Ganeva M, Ene-Iordache B, Gaspari F, Perna A, Bossi A, Trevisan R, Dodesini AR, Remuzzi G: Bergamo nephrologic diabetes complications trial (BENEDICT) investigators: preventing microalbuminuria in type 2 diabetes. N Engl J Med. 2004, 351 (19): 1941-1951. 10.1056/NEJMoa042167.CrossRefPubMed
5.
go back to reference Sarafidis PA, Khosla N, Bakris GL: Antihypertensive therapy in the presence of proteinuria. Am J Kidney Dis. 2007, 49 (1): 12-26. 10.1053/j.ajkd.2006.10.014.CrossRefPubMed Sarafidis PA, Khosla N, Bakris GL: Antihypertensive therapy in the presence of proteinuria. Am J Kidney Dis. 2007, 49 (1): 12-26. 10.1053/j.ajkd.2006.10.014.CrossRefPubMed
6.
go back to reference Kidney Disease Outcomes Quality Initiative (K/DOQI): K/DOQI clinical practice guidelines on hypertension and antihypertensive agents in chronic kidney disease. Am J Kidney Dis. 2004, 43 (5 Suppl 1): S1-S290. Kidney Disease Outcomes Quality Initiative (K/DOQI): K/DOQI clinical practice guidelines on hypertension and antihypertensive agents in chronic kidney disease. Am J Kidney Dis. 2004, 43 (5 Suppl 1): S1-S290.
7.
go back to reference Levey AS, De Jong PE, Coresh J, Nahas ME, Astor BC, Matsushita K, Gansevoort RT, Kasiske BL, Eckardt KU: The definition, classification and prognosis of chronic kidney disease: a KDIGO controversies conference report. Kidney Int. 2011, 80 (1): 17-28. 10.1038/ki.2010.483.CrossRefPubMed Levey AS, De Jong PE, Coresh J, Nahas ME, Astor BC, Matsushita K, Gansevoort RT, Kasiske BL, Eckardt KU: The definition, classification and prognosis of chronic kidney disease: a KDIGO controversies conference report. Kidney Int. 2011, 80 (1): 17-28. 10.1038/ki.2010.483.CrossRefPubMed
8.
go back to reference Stevens LA, Fares G, Fleming J, Martin D, Murthy K, Qiu J, Stark PC, Uhlig K, Van Lente F, Levey AS: Low rates of testing and diagnostic codes usage in a commercial clinical laboratory: evidence for lack of physician awareness of chronic kidney disease. J Am Soc Nephrol. 2005, 16 (8): 2439-2448. 10.1681/ASN.2005020192.CrossRefPubMed Stevens LA, Fares G, Fleming J, Martin D, Murthy K, Qiu J, Stark PC, Uhlig K, Van Lente F, Levey AS: Low rates of testing and diagnostic codes usage in a commercial clinical laboratory: evidence for lack of physician awareness of chronic kidney disease. J Am Soc Nephrol. 2005, 16 (8): 2439-2448. 10.1681/ASN.2005020192.CrossRefPubMed
9.
go back to reference Lea JP, McClellan WM, Melcher C, Gladstone E, Hostetter T: CKD risk factors reported by primary care physicians: do guidelines make a difference?. Am J Kidney Dis. 2006, 47 (1): 72-77. 10.1053/j.ajkd.2005.09.027.CrossRefPubMed Lea JP, McClellan WM, Melcher C, Gladstone E, Hostetter T: CKD risk factors reported by primary care physicians: do guidelines make a difference?. Am J Kidney Dis. 2006, 47 (1): 72-77. 10.1053/j.ajkd.2005.09.027.CrossRefPubMed
10.
go back to reference Litvin CB, Nietert PJ, Wessell AM, Jenkins RG, Ornstein SM: Recognition and management of CKD in primary care. Am J Kidney Dis. 2011, 57 (4): 646-647. 10.1053/j.ajkd.2010.11.013.CrossRefPubMedPubMedCentral Litvin CB, Nietert PJ, Wessell AM, Jenkins RG, Ornstein SM: Recognition and management of CKD in primary care. Am J Kidney Dis. 2011, 57 (4): 646-647. 10.1053/j.ajkd.2010.11.013.CrossRefPubMedPubMedCentral
11.
go back to reference Anandarajah S, Tai T, de Lusignan S, Stevens P, O’Donoghue D, Walker M, Hilton S: The validity of searching routinely collected general practice computer data to identify patients with chronic kidney disease (CKD): a manual review of 500 medical records. Nephrol Dial Transplant. 2005, 20 (10): 2089-2096. 10.1093/ndt/gfi006.CrossRefPubMed Anandarajah S, Tai T, de Lusignan S, Stevens P, O’Donoghue D, Walker M, Hilton S: The validity of searching routinely collected general practice computer data to identify patients with chronic kidney disease (CKD): a manual review of 500 medical records. Nephrol Dial Transplant. 2005, 20 (10): 2089-2096. 10.1093/ndt/gfi006.CrossRefPubMed
12.
go back to reference Chase HS, Radhakrishnan J, Shirazian S, Rao MK, Vawdrey DK: Under-documentation of chronic kidney disease in the electronic health record in outpatients. J Am Med Inform Assoc. 2010, 17 (5): 588-594. 10.1136/jamia.2009.001396.CrossRefPubMedPubMedCentral Chase HS, Radhakrishnan J, Shirazian S, Rao MK, Vawdrey DK: Under-documentation of chronic kidney disease in the electronic health record in outpatients. J Am Med Inform Assoc. 2010, 17 (5): 588-594. 10.1136/jamia.2009.001396.CrossRefPubMedPubMedCentral
13.
go back to reference de Lusignan S, Chan T, Stevens P, O’Donoghue D, Hague N, Dzregah B, Van Vlymen J, Walker M, Hilton S: Identifying patients with chronic kidney disease from general practice computer records. Fam Pract. 2005, 22 (3): 234-241. 10.1093/fampra/cmi026.CrossRefPubMed de Lusignan S, Chan T, Stevens P, O’Donoghue D, Hague N, Dzregah B, Van Vlymen J, Walker M, Hilton S: Identifying patients with chronic kidney disease from general practice computer records. Fam Pract. 2005, 22 (3): 234-241. 10.1093/fampra/cmi026.CrossRefPubMed
14.
go back to reference Guessous I, McClellan W, Vupputuri S, Wasse H: Low documentation of chronic kidney disease among high-risk patients in a managed care population: a retrospective cohort study. BMC Nephrol. 2009, 10: 25-10.1186/1471-2369-10-25.CrossRefPubMedPubMedCentral Guessous I, McClellan W, Vupputuri S, Wasse H: Low documentation of chronic kidney disease among high-risk patients in a managed care population: a retrospective cohort study. BMC Nephrol. 2009, 10: 25-10.1186/1471-2369-10-25.CrossRefPubMedPubMedCentral
15.
go back to reference Grams ME, Plantinga LC, Hedgeman E, Saran R, Myers GL, Williams DE, Powe NR, CDC CKD Surveillance Team: Validation of CKD and related conditions in existing data sets: a systematic review. Am J Kidney Dis. 2011, 57 (1): 44-54. 10.1053/j.ajkd.2010.05.013.CrossRefPubMed Grams ME, Plantinga LC, Hedgeman E, Saran R, Myers GL, Williams DE, Powe NR, CDC CKD Surveillance Team: Validation of CKD and related conditions in existing data sets: a systematic review. Am J Kidney Dis. 2011, 57 (1): 44-54. 10.1053/j.ajkd.2010.05.013.CrossRefPubMed
16.
go back to reference Simborg DW, Starfield BH, Horn SD, Yourtee SA: Information factors affecting problem follow-up in ambulatory care. Med Care. 1976, 14 (10): 848-856. 10.1097/00005650-197610000-00005.CrossRefPubMed Simborg DW, Starfield BH, Horn SD, Yourtee SA: Information factors affecting problem follow-up in ambulatory care. Med Care. 1976, 14 (10): 848-856. 10.1097/00005650-197610000-00005.CrossRefPubMed
17.
go back to reference Hartung DM, Hunt J, Siemienczuk J, Miller H, Touchette DR: Clinical implications of an accurate problem list on heart failure treatment. J Gen Intern Med. 2005, 20 (2): 143-147. 10.1111/j.1525-1497.2005.40206.x.CrossRefPubMedPubMedCentral Hartung DM, Hunt J, Siemienczuk J, Miller H, Touchette DR: Clinical implications of an accurate problem list on heart failure treatment. J Gen Intern Med. 2005, 20 (2): 143-147. 10.1111/j.1525-1497.2005.40206.x.CrossRefPubMedPubMedCentral
18.
go back to reference Tang PC, Ralston M, Arrigotti MF, Qureshi L, Graham J: Comparison of methodologies for calculating quality measures based on administrative data versus clinical data from an electronic health record system: implications for performance measures. J Am Med Inform Assoc. 2007, 14 (1): 10-15.CrossRefPubMedPubMedCentral Tang PC, Ralston M, Arrigotti MF, Qureshi L, Graham J: Comparison of methodologies for calculating quality measures based on administrative data versus clinical data from an electronic health record system: implications for performance measures. J Am Med Inform Assoc. 2007, 14 (1): 10-15.CrossRefPubMedPubMedCentral
19.
go back to reference National Kidney Foundation: K/DOQI clinical practice guidelines for chronic kidney disease: evaluation, classification, and stratification. Am J Kidney Dis. 2002, 39 (2 Suppl 1): S1-S266. National Kidney Foundation: K/DOQI clinical practice guidelines for chronic kidney disease: evaluation, classification, and stratification. Am J Kidney Dis. 2002, 39 (2 Suppl 1): S1-S266.
20.
go back to reference Sequist TD, Gandhi TK, Karson AS, Fiskio JM, Bugbee D, Sperling M, Cook EF, Orav EJ, Fairchild DG, Bates DW: A randomized trial of electronic clinical reminders to improve quality of care for diabetes and coronary artery disease. J Am Med Inform Assoc. 2005, 12 (4): 431-437. 10.1197/jamia.M1788.CrossRefPubMedPubMedCentral Sequist TD, Gandhi TK, Karson AS, Fiskio JM, Bugbee D, Sperling M, Cook EF, Orav EJ, Fairchild DG, Bates DW: A randomized trial of electronic clinical reminders to improve quality of care for diabetes and coronary artery disease. J Am Med Inform Assoc. 2005, 12 (4): 431-437. 10.1197/jamia.M1788.CrossRefPubMedPubMedCentral
21.
go back to reference Wright A, Feblowitz J, Maloney FL, Henkin S, Bates DW: Use of an electronic problem list by primary care providers and specialists. J Gen Intern Med. 2012, 27 (8): 968-973. 10.1007/s11606-012-2033-5.CrossRefPubMedPubMedCentral Wright A, Feblowitz J, Maloney FL, Henkin S, Bates DW: Use of an electronic problem list by primary care providers and specialists. J Gen Intern Med. 2012, 27 (8): 968-973. 10.1007/s11606-012-2033-5.CrossRefPubMedPubMedCentral
22.
go back to reference Wright A, Pang J, Feblowitz JC, Maloney FL, Wilcox AR, McLoughlin KS, Ramelson H, Schneider L, Bates DW: Improving completeness of electronic problem lists through clinical decision support: a randomized, controlled trial. J Am Med Inform Assoc. 2012, 19 (4): 555-561. 10.1136/amiajnl-2011-000521.CrossRefPubMedPubMedCentral Wright A, Pang J, Feblowitz JC, Maloney FL, Wilcox AR, McLoughlin KS, Ramelson H, Schneider L, Bates DW: Improving completeness of electronic problem lists through clinical decision support: a randomized, controlled trial. J Am Med Inform Assoc. 2012, 19 (4): 555-561. 10.1136/amiajnl-2011-000521.CrossRefPubMedPubMedCentral
23.
go back to reference Kent DM, Jafar TH, Hayward RA, Tighiouart H, Landa M, de Jong P, de Zeeuw D, Remuzzi G, Kamper AL, Levey AS: Progression risk, urinary protein excretion, and treatment effects of angiotensin-converting enzyme inhibitors in nondiabetic kidney disease. J Am Soc Nephrol. 2007, 18 (6): 1959-1965. 10.1681/ASN.2006101081.CrossRefPubMed Kent DM, Jafar TH, Hayward RA, Tighiouart H, Landa M, de Jong P, de Zeeuw D, Remuzzi G, Kamper AL, Levey AS: Progression risk, urinary protein excretion, and treatment effects of angiotensin-converting enzyme inhibitors in nondiabetic kidney disease. J Am Soc Nephrol. 2007, 18 (6): 1959-1965. 10.1681/ASN.2006101081.CrossRefPubMed
24.
go back to reference Jones CA, McQuillan GM, Kusek JW, Eberhardt MS, Herman WH, Coresh J, Salive M, Jones CP, Agodoa LY: Serum creatinine levels in the US population: third national health and nutrition examination survey. Am J Kidney Dis. 1998, 32 (6): 992-999. 10.1016/S0272-6386(98)70074-5.CrossRefPubMed Jones CA, McQuillan GM, Kusek JW, Eberhardt MS, Herman WH, Coresh J, Salive M, Jones CP, Agodoa LY: Serum creatinine levels in the US population: third national health and nutrition examination survey. Am J Kidney Dis. 1998, 32 (6): 992-999. 10.1016/S0272-6386(98)70074-5.CrossRefPubMed
25.
go back to reference Rodriguez RA, Hernandez GT, O’Hare AM, Glidden DV, Perez-Stable EJ: Creatinine levels among mexican americans, puerto ricans, and cuban americans in the hispanic health and nutrition examination survey. Kidney Int. 2004, 66 (6): 2368-2373. 10.1111/j.1523-1755.2004.66025.x.CrossRefPubMed Rodriguez RA, Hernandez GT, O’Hare AM, Glidden DV, Perez-Stable EJ: Creatinine levels among mexican americans, puerto ricans, and cuban americans in the hispanic health and nutrition examination survey. Kidney Int. 2004, 66 (6): 2368-2373. 10.1111/j.1523-1755.2004.66025.x.CrossRefPubMed
26.
go back to reference Gansevoort RT, de Jong PE: The case for using albuminuria in staging chronic kidney disease. J Am Soc Nephrol. 2009, 20 (3): 465-468. 10.1681/ASN.2008111212.CrossRefPubMed Gansevoort RT, de Jong PE: The case for using albuminuria in staging chronic kidney disease. J Am Soc Nephrol. 2009, 20 (3): 465-468. 10.1681/ASN.2008111212.CrossRefPubMed
27.
go back to reference Gansevoort RT, Matsushita K, van der Velde M, Astor BC, Woodward M, Levey AS, Jong PE, Coresh J, Gansevoort RT, Matsushita K, van der Velde M, Astor BC, Woodward M, Levey AS, de Jong PE, Coresh J, El-Nahas M, Eckardt KU, Kasiske BL, Ninomiya T, Chalmers J, Macmahon S, Tonelli M, Hemmelgarn B, Wang Y, Atkins RC, Polkinghorne KR, Chadban SJ, Shankar A, The Chronic Kidney Disease Prognosis Consortium, et al: Lower estimated GFR and higher albuminuria are associated with adverse kidney outcomes in both general and high-risk populations: a collaborative meta-analysis of general and high-risk population cohorts. Kidney Int. 2011, 80 (1): 93-104. 10.1038/ki.2010.531.CrossRefPubMedPubMedCentral Gansevoort RT, Matsushita K, van der Velde M, Astor BC, Woodward M, Levey AS, Jong PE, Coresh J, Gansevoort RT, Matsushita K, van der Velde M, Astor BC, Woodward M, Levey AS, de Jong PE, Coresh J, El-Nahas M, Eckardt KU, Kasiske BL, Ninomiya T, Chalmers J, Macmahon S, Tonelli M, Hemmelgarn B, Wang Y, Atkins RC, Polkinghorne KR, Chadban SJ, Shankar A, The Chronic Kidney Disease Prognosis Consortium, et al: Lower estimated GFR and higher albuminuria are associated with adverse kidney outcomes in both general and high-risk populations: a collaborative meta-analysis of general and high-risk population cohorts. Kidney Int. 2011, 80 (1): 93-104. 10.1038/ki.2010.531.CrossRefPubMedPubMedCentral
28.
go back to reference Parchman ML, Pugh JA, Romero RL, Bowers KW: Competing demands or clinical inertia: the case of elevated glycosylated hemoglobin. Ann Fam Med. 2007, 5 (3): 196-201. 10.1370/afm.679.CrossRefPubMedPubMedCentral Parchman ML, Pugh JA, Romero RL, Bowers KW: Competing demands or clinical inertia: the case of elevated glycosylated hemoglobin. Ann Fam Med. 2007, 5 (3): 196-201. 10.1370/afm.679.CrossRefPubMedPubMedCentral
29.
go back to reference Allen AS, Forman JP, Orav EJ, Bates DW, Denker BM, Sequist TD: Primary care management of chronic kidney disease. J Gen Intern Med. 2011, 26 (4): 386-392. 10.1007/s11606-010-1523-6.CrossRefPubMed Allen AS, Forman JP, Orav EJ, Bates DW, Denker BM, Sequist TD: Primary care management of chronic kidney disease. J Gen Intern Med. 2011, 26 (4): 386-392. 10.1007/s11606-010-1523-6.CrossRefPubMed
30.
go back to reference Abdel-Kader K, Fischer GS, Li J, Moore CG, Hess R, Unruh ML: Automated clinical reminders for primary care providers in the care of CKD: a small cluster-randomized controlled trial. Am J Kidney Dis. 2011, 58 (6): 894-902. 10.1053/j.ajkd.2011.08.028.CrossRefPubMedPubMedCentral Abdel-Kader K, Fischer GS, Li J, Moore CG, Hess R, Unruh ML: Automated clinical reminders for primary care providers in the care of CKD: a small cluster-randomized controlled trial. Am J Kidney Dis. 2011, 58 (6): 894-902. 10.1053/j.ajkd.2011.08.028.CrossRefPubMedPubMedCentral
31.
go back to reference Powers BJ, Olsen MK, Smith VA, Woolson RF, Bosworth HB, Oddone EZ: Measuring blood pressure for decision making and quality reporting: where and how many measures?. Ann Intern Med. 2011, 154 (12): 781-10.7326/0003-4819-154-12-201106210-00005.CrossRefPubMed Powers BJ, Olsen MK, Smith VA, Woolson RF, Bosworth HB, Oddone EZ: Measuring blood pressure for decision making and quality reporting: where and how many measures?. Ann Intern Med. 2011, 154 (12): 781-10.7326/0003-4819-154-12-201106210-00005.CrossRefPubMed
Metadata
Title
Electronic problem list documentation of chronic kidney disease and quality of care
Authors
Lipika Samal
Jeffrey A Linder
David W Bates
Adam Wright
Publication date
01-12-2014
Publisher
BioMed Central
Published in
BMC Nephrology / Issue 1/2014
Electronic ISSN: 1471-2369
DOI
https://doi.org/10.1186/1471-2369-15-70

Other articles of this Issue 1/2014

BMC Nephrology 1/2014 Go to the issue