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BMC Infectious Diseases
Published in: BMC Infectious Diseases 1/2006

Open Access 01-12-2006 | Case report

Successful treatment of Candida parapsilosis mural endocarditis with combined caspofungin and voriconazole

Authors: Víctor López-Ciudad, María J Castro-Orjales, Cristóbal León, César Sanz-Rodríguez, María J de la Torre-Fernández, Miguel A Pérez de Juan-Romero, María D Collell-Llach, María D Díaz-López

Published in: BMC Infectious Diseases | Issue 1/2006

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Abstract

Background

Fungal mural endocarditis is a rare entity in which the antemortem diagnosis is seldom made. Seven cases of mural endocarditis caused by Candida spp. have been collected from literature and six of these patients died after treatment with amphotericin B.

Case presentation

We report a case of mural endocarditis diagnosed by transesophageal echocardiogram and positive blood cultures to Candida parapsilosis. Because blood cultures continued to yield C. parapsilosis despite caspofungin monotherapy, treatment with voriconazole was added.

Conclusion

This is the first description of successful treatment of C. parapsilosis mural endocarditis with caspofungin and voriconazole.
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Metadata
Title
Successful treatment of Candida parapsilosis mural endocarditis with combined caspofungin and voriconazole
Authors
Víctor López-Ciudad
María J Castro-Orjales
Cristóbal León
César Sanz-Rodríguez
María J de la Torre-Fernández
Miguel A Pérez de Juan-Romero
María D Collell-Llach
María D Díaz-López
Publication date
01-12-2006
Publisher
BioMed Central
Published in
BMC Infectious Diseases / Issue 1/2006
Electronic ISSN: 1471-2334
DOI
https://doi.org/10.1186/1471-2334-6-73

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