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Published in: BMC Cardiovascular Disorders 1/2009

Open Access 01-12-2009 | Research article

Long-term survival after initial hospital admission for peripheral arterial disease in the lower extremities

Authors: I Vaartjes, GJ de Borst, JB Reitsma, A de Bruin, FL Moll, DE Grobbee, ML Bots

Published in: BMC Cardiovascular Disorders | Issue 1/2009

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Abstract

Background

As the population ages, peripheral arterial disease (PAD) in the lower extremities will become a larger public health problem. Awareness in patients as well clinicians of the high risk of morbidity and mortality is important but seems currently low. Insights in absolute mortality risks following admission for PAD in the lower extremities can be useful to improve awareness as they are easy to interpret.

Methods

A nationwide cohort of 4,158 patients with an initial admission for PAD in the lower extremities was identified through linkage of the national hospital and population register in 1997 and 2000.

Results

Over 60% of 4,158 patients were men. 28 days, 1 year and 5 year mortality risk were 2.4%, 10.3% and 31.0% for men and 3.5%, 10.4% and 27.4% for women. Coronary heart disease and stroke were frequent cause of death. Five years mortality risk was higher for men compared to women (HR 1.36, 95% CI 1.21–1.53).

Conclusion

In conclusion, our findings demonstrate that, 5 year mortality risk is high, especially in men and comparable to that of patients admitted for acute myocardial infarction or ischemic stroke. Though, in general population the awareness of the severity of PAD in the lower extremities is significantly lower than that for any other cardiovascular disease and it seems that cardiovascular risk factor management for prevention in PAD patients is very modest.
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Metadata
Title
Long-term survival after initial hospital admission for peripheral arterial disease in the lower extremities
Authors
I Vaartjes
GJ de Borst
JB Reitsma
A de Bruin
FL Moll
DE Grobbee
ML Bots
Publication date
01-12-2009
Publisher
BioMed Central
Published in
BMC Cardiovascular Disorders / Issue 1/2009
Electronic ISSN: 1471-2261
DOI
https://doi.org/10.1186/1471-2261-9-43

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