Published in:
01-03-2020 | Mites | Veterinary Dermatology (A Rostaher and N Fischer, Section Editors)
What Can We Learn from Canine Atopic Dermatitis History?
Authors:
Pascal Prelaud, Aurore Laprais
Published in:
Current Dermatology Reports
|
Issue 1/2020
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Abstract
Purpose of Review
Understanding the origin and shaping the current knowledge of canine atopic dermatitis (cAD) with an emphasis on its similarities and differences with its human counterpart, human atopic dermatitis (hAD), has been the purpose of this study.
Recent Finding
Fundamental research on the ethiopathogenesis and recent specific therapeutic findings have gradually reclassified cAD from a single disease to a multifactorial syndrome.
Summary
From first being referred to as “red mange” or “canine eczema” in a dog reacting to ragweed pollen, cAD has then been considered to be the canine counterpart of hAD. Both conditions share comparable historical discoveries as well as treatment evolutions such as skin barrier defects, the use of cyclosporine, proactive topical corticosteroids, or recent use of biotherapies. More recent discoveries have however shown some fundamental differences between both conditions such as the place of flea infestation and Malassezia infections in the dog or the hygiene theory in human. As in human medicine*, cAD is also a source of conceptual and nosological remaining controversies.