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Journal of NeuroVirology
Published in: Journal of NeuroVirology 2/2020

01-04-2020 | Herpes Virus | Case Report

Herpes simplex virus-1 as a rare etiology of isolated acute cerebellitis: case report and literature review

Authors: Cem Paketci, Pinar Edem, Canan Okumus, Fatma Ceren Sarioglu, Erhan Bayram, Semra Hiz, Uluç Yis

Published in: Journal of NeuroVirology | Issue 2/2020

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Abstract

Acute cerebellitis is one of the most common cerebellar disorders and occurs due to para-infectious, post-infectious, or post-vaccination cerebellar inflammation. Herpes simplex virus-1 (HSV-1) is known as a common infectious cause of sporadic encephalitis. Cerebellar involvement of HSV-1 is rare and almost always associated with meningoencephalitis. To date, HSV-1 has been identified as the cause of acute isolated cerebellitis in only two patients. Here we report another case of isolated acute cerebellitis caused by HSV-1 in a 20-month-old boy.
Literature
Ciardi M, Giacchetti G, Fedele CG, Tenorio A, Brandi A, Libertone R, Ajassa C, Borgese L, Delia S (2003) Acute cerebellitis caused by herpes simplex virus type 1. Clin Infect Dis 36:50–54CrossRef
Connolly AM, Dodson WE, Prensky AL, Rust RS (1994) Course and outcome of acute cerebellar ataxia. Ann Neurol 35:673–679CrossRef
De Bruecker Y, Claus F, Demaerel P, Ballaux F, Sciot R, Lagae L, Buyse G, Wilms G (2004) MRI findings in acute cerebellitis. Euro Radiol 14:1478–1483CrossRef
Lancella L, Esposito S, Galli ML, Bozzola E (2017) Acute cerebellitis in children: an eleven year retrospective multicentric study in Italy. Ital J Pediatr 43:54CrossRef
Nussinovitch M, Prais D, Volovitz B, Shapiro R, Amir J (2003) Post-infectious acute cerebellar ataxia in children. Clin Pediatr (Phila) 42:581–584CrossRef
Rozenberg F, Deback C, Agut H (2011) Herpes simplex encephalitis: from virus to therapy. Infect Disord Drug Targets 11:235–250CrossRef
Tlili-Graiess K, Mhiri Souei M, Mlaiki B, Arifa N, Moulahi H, Jemni Gharbi H, Yacoub M, Essoussi M (2006) Imaging of acute cerebellitis in children. Report of 4 cases. J Neuroradiol 33:38–44CrossRef
Metadata
Title
Herpes simplex virus-1 as a rare etiology of isolated acute cerebellitis: case report and literature review
Authors
Cem Paketci
Pinar Edem
Canan Okumus
Fatma Ceren Sarioglu
Erhan Bayram
Semra Hiz
Uluç Yis
Publication date
01-04-2020
Publisher
Springer International Publishing
Published in
Journal of NeuroVirology / Issue 2/2020
Print ISSN: 1355-0284
Electronic ISSN: 1538-2443
DOI
https://doi.org/10.1007/s13365-019-00802-6

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