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Published in: Insights into Imaging 2/2017

Open Access 01-04-2017 | Review

Utility of magnetic resonance imaging in the evaluation of left ventricular thickening

Authors: Nicholas Fulton, Prabhakar Rajiah

Published in: Insights into Imaging | Issue 2/2017

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Abstract

Left ventricular (LV) thickening can be due to hypertrophy (concentric, asymmetric, eccentric) or remodelling (concentric or asymmetric). Pathological thickening may be caused by pressure overload, volume overload, infiltrative disorders, hypertrophic cardiomyopathy, athlete’s heart or neoplastic infiltration. Magnetic resonance imaging (MRI) plays an important role in the comprehensive evaluation of LV thickening, including: establishing diagnosis, determining LV geometry, establishing aetiology, quantification, identifying prognostic factors, serial follow-up and treatment response. In this article, we review the aetiologies and pathophysiology of LV thickening, and demonstrate the comprehensive role of MRI in the evaluation of LV thickening.

Teaching Points

MRI plays an important role in the evaluation of LV thickening.
LV thickening can be due to either hypertrophy or remodelling.
Pathological thickening can be due to pressure/volume overload or infiltrative disorders.
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Literature
2.
go back to reference Puntmann V, Jahnke C, Gebker R (2010) Usefulness of magnetic resonance imaging to distinguish hypertensive and hypertrophic cardiomyopathy. Am J Cardiol 106(7):1016–1022CrossRefPubMed Puntmann V, Jahnke C, Gebker R (2010) Usefulness of magnetic resonance imaging to distinguish hypertensive and hypertrophic cardiomyopathy. Am J Cardiol 106(7):1016–1022CrossRefPubMed
3.
go back to reference Díez J (2007) Mechanisms of cardiac fibrosis in hypertension. J Clin Hypertens 9(7):546–550CrossRef Díez J (2007) Mechanisms of cardiac fibrosis in hypertension. J Clin Hypertens 9(7):546–550CrossRef
4.
go back to reference Levy D, Garrison RJ, Savage DD, Kannel WB, Castelli WP (1990) Prognostic implications of echocardiographically determined left ventricular mass in the Framingham Heart Study. N Engl J Med 322(22):1561–1566CrossRefPubMed Levy D, Garrison RJ, Savage DD, Kannel WB, Castelli WP (1990) Prognostic implications of echocardiographically determined left ventricular mass in the Framingham Heart Study. N Engl J Med 322(22):1561–1566CrossRefPubMed
5.
go back to reference Casale PN, Devereux RB, Milner M et al (1986) Value of echocardiographic measurement of left ventricular mass in predicting cardiovascular morbid events in hypertensive men. Ann Intern Med 105(2):173–178CrossRefPubMed Casale PN, Devereux RB, Milner M et al (1986) Value of echocardiographic measurement of left ventricular mass in predicting cardiovascular morbid events in hypertensive men. Ann Intern Med 105(2):173–178CrossRefPubMed
6.
go back to reference Koren MJ, Devereux RB, Casale PN, Savage DD, Laragh JH (1991) Relation of left ventricular mass and geometry to morbidity and mortality in uncomplicated essential hypertension. Ann Intern Med 114(5):345–352CrossRefPubMed Koren MJ, Devereux RB, Casale PN, Savage DD, Laragh JH (1991) Relation of left ventricular mass and geometry to morbidity and mortality in uncomplicated essential hypertension. Ann Intern Med 114(5):345–352CrossRefPubMed
7.
go back to reference Olsen MH, Wachtell K, Hermann KL et al (2002) Is cardiovascular remodeling in patients with essential hypertension related to more than high blood pressure? A LIFE substudy. Am Heart J 144(3):530–537CrossRefPubMed Olsen MH, Wachtell K, Hermann KL et al (2002) Is cardiovascular remodeling in patients with essential hypertension related to more than high blood pressure? A LIFE substudy. Am Heart J 144(3):530–537CrossRefPubMed
8.
go back to reference Devereux RB, Alonso DR, Lutas EM et al (1986) Echocardiographic assessment of left ventricular hypertrophy: Comparison to necropsy findings. Am J Cardiol 57(6):450–458CrossRefPubMed Devereux RB, Alonso DR, Lutas EM et al (1986) Echocardiographic assessment of left ventricular hypertrophy: Comparison to necropsy findings. Am J Cardiol 57(6):450–458CrossRefPubMed
9.
go back to reference Armstrong AC, Gidding S, Gjesdal O et al (2012) LV mass assessed by echocardiography and CMR, cardiovascular outcomes, and medical practice. J Am Coll Cardiol Img 5(8):837–848CrossRef Armstrong AC, Gidding S, Gjesdal O et al (2012) LV mass assessed by echocardiography and CMR, cardiovascular outcomes, and medical practice. J Am Coll Cardiol Img 5(8):837–848CrossRef
10.
go back to reference Senda Y, Tohkai H, Kimura M et al (1990) ECG-gated cardiac scan and echocardiographic assessments of left ventricular hypertrophy: reversal by 6-month treatment with diltiazem. J Cardiovasc Pharmacol 16(2):298–304CrossRefPubMed Senda Y, Tohkai H, Kimura M et al (1990) ECG-gated cardiac scan and echocardiographic assessments of left ventricular hypertrophy: reversal by 6-month treatment with diltiazem. J Cardiovasc Pharmacol 16(2):298–304CrossRefPubMed
11.
go back to reference Schlosser T, Mohrs OK, Magedanz A, Voigtländer T, Schmermund A, Barkhausen J (2007) Assessment of left ventricular function and mass in patients undergoing computed tomography (CT) coronary angiography using 64-detector-row CT: comparison to magnetic resonance imaging. Acta Radiol 48(1):30–35CrossRefPubMed Schlosser T, Mohrs OK, Magedanz A, Voigtländer T, Schmermund A, Barkhausen J (2007) Assessment of left ventricular function and mass in patients undergoing computed tomography (CT) coronary angiography using 64-detector-row CT: comparison to magnetic resonance imaging. Acta Radiol 48(1):30–35CrossRefPubMed
12.
go back to reference Belge B, Coche E, Pasquet A, Vanoverschelde J-LJ, Gerber BL (2006) Accurate estimation of global and regional cardiac function by retrospectively gated multidetector row computed tomography: comparison with cine magnetic resonance imaging. Eur Radiol 16(7):1424–1433CrossRefPubMed Belge B, Coche E, Pasquet A, Vanoverschelde J-LJ, Gerber BL (2006) Accurate estimation of global and regional cardiac function by retrospectively gated multidetector row computed tomography: comparison with cine magnetic resonance imaging. Eur Radiol 16(7):1424–1433CrossRefPubMed
13.
go back to reference La Gerche A, Taylor AJ, Prior DL (2009) Athlete’s heart: the potential for multimodality imaging to address the critical remaining questions. JACC Cardiovasc Imaging 2:350–363CrossRefPubMed La Gerche A, Taylor AJ, Prior DL (2009) Athlete’s heart: the potential for multimodality imaging to address the critical remaining questions. JACC Cardiovasc Imaging 2:350–363CrossRefPubMed
14.
go back to reference Grothue F et al (2002) Comparison of interstudy reproducibility of cardiovascular magnetic resonance with two-dimensional echocardiography in normal subjects and in patients with heart failure or left ventricular hypertrophy. Am J Cardiol 90(1):29–34CrossRef Grothue F et al (2002) Comparison of interstudy reproducibility of cardiovascular magnetic resonance with two-dimensional echocardiography in normal subjects and in patients with heart failure or left ventricular hypertrophy. Am J Cardiol 90(1):29–34CrossRef
15.
go back to reference Tee M, Noble JA, Bluemke D (2013) Imaging techniques for cardiac strain and deformation: comparison of echocardiography, cardiac magnetic resonance and cardiac computed tomography. Expert Rev Cardiovasc Ther 11(2):221–231CrossRefPubMed Tee M, Noble JA, Bluemke D (2013) Imaging techniques for cardiac strain and deformation: comparison of echocardiography, cardiac magnetic resonance and cardiac computed tomography. Expert Rev Cardiovasc Ther 11(2):221–231CrossRefPubMed
16.
go back to reference Ginat DT, Fong MW, Tuttle DJ et al (2011) Cardiac imaging: Part 1, MR pulse sequences, imaging planes, and basic anatomy. Am J Roentgenol 197(4):808–815CrossRef Ginat DT, Fong MW, Tuttle DJ et al (2011) Cardiac imaging: Part 1, MR pulse sequences, imaging planes, and basic anatomy. Am J Roentgenol 197(4):808–815CrossRef
17.
go back to reference Coelho-Filho OR, Rickers C, Kwong RY, Jerosch-Herold M (2013) MR myocardial perfusion imaging. Radiology 266(3):701–715CrossRefPubMed Coelho-Filho OR, Rickers C, Kwong RY, Jerosch-Herold M (2013) MR myocardial perfusion imaging. Radiology 266(3):701–715CrossRefPubMed
18.
go back to reference Karamitsos TD, Piechnik SK, Banypersard SM et al (2013) Noncontrast T1 mapping for the diagnosis of cardiac amyloidosis. J Am Coll Cardiol Img 6(4):488–497CrossRef Karamitsos TD, Piechnik SK, Banypersard SM et al (2013) Noncontrast T1 mapping for the diagnosis of cardiac amyloidosis. J Am Coll Cardiol Img 6(4):488–497CrossRef
19.
go back to reference Sado DM, White SK, Piechnik SK et al (2013) Identification and assessment of Anderson-Fabry disease by cardiovascular magnetic resonance noncontrast myocardial T1 mapping. Circ Cardiovasc Imaging 6(3):392–398CrossRefPubMed Sado DM, White SK, Piechnik SK et al (2013) Identification and assessment of Anderson-Fabry disease by cardiovascular magnetic resonance noncontrast myocardial T1 mapping. Circ Cardiovasc Imaging 6(3):392–398CrossRefPubMed
20.
go back to reference Sado DM, Maestrini V, Piechnik SK et al (2015) Noncontrast myocardial T1 mapping using cardiovascular magnetic resonance for iron overload. J Magn Reson Imaging 41(6):1505–1511CrossRefPubMed Sado DM, Maestrini V, Piechnik SK et al (2015) Noncontrast myocardial T1 mapping using cardiovascular magnetic resonance for iron overload. J Magn Reson Imaging 41(6):1505–1511CrossRefPubMed
21.
go back to reference Maceira AM, Prasad SK, Khan M, Pennell DJ (2006) Normalized left ventricular systolic and diastolic function by steady state free precession cardiovascular magnetic resonance. J Cardiovasc Magn Reson 8(3):417–426CrossRefPubMed Maceira AM, Prasad SK, Khan M, Pennell DJ (2006) Normalized left ventricular systolic and diastolic function by steady state free precession cardiovascular magnetic resonance. J Cardiovasc Magn Reson 8(3):417–426CrossRefPubMed
22.
go back to reference Dweck MR, Joshi S, Murigu T et al (2012) Left ventricular remodeling and hypertrophy in patients with aortic stenosis: insights from cardiovascular magnetic resonance. J Cardiovasc Magn Reson 14(1):50CrossRefPubMedPubMedCentral Dweck MR, Joshi S, Murigu T et al (2012) Left ventricular remodeling and hypertrophy in patients with aortic stenosis: insights from cardiovascular magnetic resonance. J Cardiovasc Magn Reson 14(1):50CrossRefPubMedPubMedCentral
23.
go back to reference Chirinos JA, Segers P, De Buyzere ML et al (2010) Left ventricular mass: allometric scaling, normative values, effect of obesity, and prognostic performance. Hypertension 56(1):91–98CrossRefPubMedPubMedCentral Chirinos JA, Segers P, De Buyzere ML et al (2010) Left ventricular mass: allometric scaling, normative values, effect of obesity, and prognostic performance. Hypertension 56(1):91–98CrossRefPubMedPubMedCentral
24.
go back to reference Muiesan ML, Salvetti M, Monteduro C et al (2004) Left ventricular concentric geometry during treatment adversely affects cardiovascular prognosis in hypertensive patients. Hypertension 43(4):731–738CrossRefPubMed Muiesan ML, Salvetti M, Monteduro C et al (2004) Left ventricular concentric geometry during treatment adversely affects cardiovascular prognosis in hypertensive patients. Hypertension 43(4):731–738CrossRefPubMed
25.
go back to reference Rodriguez JCL, Amadu AM, Dastidar AG, et al. (2016) Comprehensive characterization of hypertensive heart disease left ventricular phenotypes. Heart 0:1–9 Rodriguez JCL, Amadu AM, Dastidar AG, et al. (2016) Comprehensive characterization of hypertensive heart disease left ventricular phenotypes. Heart 0:1–9
26.
go back to reference Andersen K, Hennersdorf M, Cohnen M et al (2009) Myocardial delayed contrast enhancement in patients with arterial hypertension: initial results of cardiac MRI. Eur J RAdiol 71:75–81CrossRefPubMed Andersen K, Hennersdorf M, Cohnen M et al (2009) Myocardial delayed contrast enhancement in patients with arterial hypertension: initial results of cardiac MRI. Eur J RAdiol 71:75–81CrossRefPubMed
27.
go back to reference Baumgartner H, Hung J, Bermejo J et al (2009) Echocardiographic assessment of valve stenosis: EAE/ASE recommendations for clinical practice. J Am Soc Echocardiogr 22(1):1–23CrossRefPubMed Baumgartner H, Hung J, Bermejo J et al (2009) Echocardiographic assessment of valve stenosis: EAE/ASE recommendations for clinical practice. J Am Soc Echocardiogr 22(1):1–23CrossRefPubMed
28.
go back to reference Smucker ML, Tedesco CL, Manning SB, Owen RM, Feldman MD (1988) Demonstration of an imbalance between coronary perfusion and excessive load as a mechanism of ischemia during stress in patients with aortic stenosis. Circulation 78(3):573–582CrossRefPubMed Smucker ML, Tedesco CL, Manning SB, Owen RM, Feldman MD (1988) Demonstration of an imbalance between coronary perfusion and excessive load as a mechanism of ischemia during stress in patients with aortic stenosis. Circulation 78(3):573–582CrossRefPubMed
29.
go back to reference Azevedo CF, Nigri M, Higuchi ML et al (2010) Prognostic significance of myocardial fibrosis quantification by histopathology and magnetic resonance imaging in patients with severe aortic valve disease. J Am Coll Cardiol 56(4):278–287CrossRefPubMed Azevedo CF, Nigri M, Higuchi ML et al (2010) Prognostic significance of myocardial fibrosis quantification by histopathology and magnetic resonance imaging in patients with severe aortic valve disease. J Am Coll Cardiol 56(4):278–287CrossRefPubMed
30.
go back to reference Herrman S, Stork S, Neimann M et al (2011) Low-gradient aortic valve stenosis: myocardial fibrosis and its influence on function and outcome. J Am Coll Cardiol 58(4):402–412CrossRef Herrman S, Stork S, Neimann M et al (2011) Low-gradient aortic valve stenosis: myocardial fibrosis and its influence on function and outcome. J Am Coll Cardiol 58(4):402–412CrossRef
31.
go back to reference Dweck MR, Joshi S, Murigu T et al (2011) Midwall fibrosis is an independent predictor of mortality in patients with aortic stenosis. J Am Coll Cardiol 58(12):1271–1279CrossRefPubMed Dweck MR, Joshi S, Murigu T et al (2011) Midwall fibrosis is an independent predictor of mortality in patients with aortic stenosis. J Am Coll Cardiol 58(12):1271–1279CrossRefPubMed
32.
go back to reference Chaturvedi A, Hobbs SK, Ling FS et al (2016) MRI evaluation prior to Transcatheter Aortic Valve Implantation (TAVI): When to acquire and how to interpret. Insights Imaging 7(2):245–254CrossRefPubMedPubMedCentral Chaturvedi A, Hobbs SK, Ling FS et al (2016) MRI evaluation prior to Transcatheter Aortic Valve Implantation (TAVI): When to acquire and how to interpret. Insights Imaging 7(2):245–254CrossRefPubMedPubMedCentral
33.
go back to reference Katta R, Rathore V, Lip G (1997) Coarctation of aorta. J Hum Hypertens 11:537–538CrossRef Katta R, Rathore V, Lip G (1997) Coarctation of aorta. J Hum Hypertens 11:537–538CrossRef
34.
go back to reference Hom JJ, Ordovas K, Reddy GP (2008) Velocity-encoded cine MR imaging in aortic coarctation: functional assessment of hemodynamic events. Radiographics 28(2):407–416CrossRefPubMed Hom JJ, Ordovas K, Reddy GP (2008) Velocity-encoded cine MR imaging in aortic coarctation: functional assessment of hemodynamic events. Radiographics 28(2):407–416CrossRefPubMed
35.
go back to reference Teis A, Sheppard MN, Alpendurada F (2010) Subaortic membrane: correlation of imaging with pathology. Eur Heart J 31(22):2822CrossRefPubMed Teis A, Sheppard MN, Alpendurada F (2010) Subaortic membrane: correlation of imaging with pathology. Eur Heart J 31(22):2822CrossRefPubMed
36.
go back to reference O’Donnell DH, Abbara S, Chaithiraphan V et al (2012) Cardiac MR imaging of non ischemic cardiomypathies: imaging protocols and spectra of appearances. Radiology 262(2):403–420CrossRefPubMed O’Donnell DH, Abbara S, Chaithiraphan V et al (2012) Cardiac MR imaging of non ischemic cardiomypathies: imaging protocols and spectra of appearances. Radiology 262(2):403–420CrossRefPubMed
37.
go back to reference Seward JB, Casaclang-Verzosa G (2010) Infiltrative cardiovascular disease. Cardiomyopathies that look alike. J Am Coll Cardiol 55(17):1769–1779CrossRefPubMed Seward JB, Casaclang-Verzosa G (2010) Infiltrative cardiovascular disease. Cardiomyopathies that look alike. J Am Coll Cardiol 55(17):1769–1779CrossRefPubMed
38.
go back to reference Maceira AM, Prasad SK, Hawkins PN, Roughton M, Pennell DJ (2008) Cardiovascular magnetic resonance and prognosis in cardiac amyloidosis. J Cardiovasc Magn Reson 10:54CrossRefPubMedPubMedCentral Maceira AM, Prasad SK, Hawkins PN, Roughton M, Pennell DJ (2008) Cardiovascular magnetic resonance and prognosis in cardiac amyloidosis. J Cardiovasc Magn Reson 10:54CrossRefPubMedPubMedCentral
39.
go back to reference Syed IS, Glockner JF, Feng D et al (2010) Role of cardiac magnetic resonance imaging in the detection of cardiac amyloidosis. JACC Cardiovasc Imaging 3(2):155–164CrossRefPubMed Syed IS, Glockner JF, Feng D et al (2010) Role of cardiac magnetic resonance imaging in the detection of cardiac amyloidosis. JACC Cardiovasc Imaging 3(2):155–164CrossRefPubMed
40.
go back to reference Karamitsos TD, Piechnik SK, Banypersad SM et al (2013) Noncontrast T1 mapping for the diagnosis of cardiac amyloidosis. JACC Cardiovasc Imaging 6(4):488–497CrossRefPubMed Karamitsos TD, Piechnik SK, Banypersad SM et al (2013) Noncontrast T1 mapping for the diagnosis of cardiac amyloidosis. JACC Cardiovasc Imaging 6(4):488–497CrossRefPubMed
41.
go back to reference Banypersad SM, Sado DM, Flett AS et al (2013) Quantification of myocardial extracellular volume fraction in systemic AL amyloidosis: an equilibrium contrast cardiovascular magnetic resonance study. Circ Cardiovasc Imaging 6(1):34–39CrossRefPubMed Banypersad SM, Sado DM, Flett AS et al (2013) Quantification of myocardial extracellular volume fraction in systemic AL amyloidosis: an equilibrium contrast cardiovascular magnetic resonance study. Circ Cardiovasc Imaging 6(1):34–39CrossRefPubMed
42.
go back to reference Seydelmann N, Wanner C, Stork S et al (2015) Fabry disease and the heart. Best Pract Res Clin Endocrinol Metabol 29:195–204CrossRef Seydelmann N, Wanner C, Stork S et al (2015) Fabry disease and the heart. Best Pract Res Clin Endocrinol Metabol 29:195–204CrossRef
43.
go back to reference Nakao S, Takenaka T, Maeda M et al (1995) An atypical variant of Fabry’s disease in men with left ventricular hypertrophy. N Engl J Med 333(5):288–293CrossRefPubMed Nakao S, Takenaka T, Maeda M et al (1995) An atypical variant of Fabry’s disease in men with left ventricular hypertrophy. N Engl J Med 333(5):288–293CrossRefPubMed
44.
go back to reference Sachdev B, Takenaka T, Teraguchi H et al (2002) Prevalence of Anderson-Fabry disease in male patients with late onset hypertrophic cardiomyopathy. Circulation 105(12):1407–1411CrossRefPubMed Sachdev B, Takenaka T, Teraguchi H et al (2002) Prevalence of Anderson-Fabry disease in male patients with late onset hypertrophic cardiomyopathy. Circulation 105(12):1407–1411CrossRefPubMed
45.
go back to reference De Cobelli F, Esposito A, Belloni E, et al. (2009) Delayed-enhanced cardiac MRI for differentiation of fabry’s disease from symmetric hypertrophic cardiomyopathy. Am J Roentgenol 192(3) De Cobelli F, Esposito A, Belloni E, et al. (2009) Delayed-enhanced cardiac MRI for differentiation of fabry’s disease from symmetric hypertrophic cardiomyopathy. Am J Roentgenol 192(3)
46.
go back to reference Yang Z, McMahon CJ, Smith LR et al (2005) Danon disease as an underrecognized cause of hypertrophic cardiomyopathy in children. Circulation 112(11):1612–1617CrossRefPubMed Yang Z, McMahon CJ, Smith LR et al (2005) Danon disease as an underrecognized cause of hypertrophic cardiomyopathy in children. Circulation 112(11):1612–1617CrossRefPubMed
47.
go back to reference Tada H, Harimura Y, Yamasaki H (2010) Utility of Real-time 3-dimensional echocardiography and magnetic resonance imaging for evaluation of Danon disease. Circulation 121:e390–e392CrossRefPubMed Tada H, Harimura Y, Yamasaki H (2010) Utility of Real-time 3-dimensional echocardiography and magnetic resonance imaging for evaluation of Danon disease. Circulation 121:e390–e392CrossRefPubMed
48.
go back to reference Piotrowska-Kownacka D, Kownacki L, Kuch M et al (2009) Cardiovascular magnetic resonance findings in a case of Danon disease. J Cardiovasc Magn Reson 11:12CrossRefPubMedPubMedCentral Piotrowska-Kownacka D, Kownacki L, Kuch M et al (2009) Cardiovascular magnetic resonance findings in a case of Danon disease. J Cardiovasc Magn Reson 11:12CrossRefPubMedPubMedCentral
49.
go back to reference Dara B, Rusconi P, Fishman J (2011) Characteristic late gadolinium enhancement pattern on cardiac magnetic resonance imaging. Cardiol Young 21:707–709CrossRefPubMed Dara B, Rusconi P, Fishman J (2011) Characteristic late gadolinium enhancement pattern on cardiac magnetic resonance imaging. Cardiol Young 21:707–709CrossRefPubMed
50.
go back to reference Stranzinger E, Ensing G, Hernandez R (2008) MR findings of endocardial fibroelastosis in children. Pediatr Radiol 38:292–296CrossRefPubMed Stranzinger E, Ensing G, Hernandez R (2008) MR findings of endocardial fibroelastosis in children. Pediatr Radiol 38:292–296CrossRefPubMed
51.
go back to reference Rajiah P, Raza S, Saboo SS et al (2016) Update on the role of cardiac magnetic resonance in acquired on ischemic cardiomyopathies. J Thorac Imaging 31(6):348–366CrossRefPubMed Rajiah P, Raza S, Saboo SS et al (2016) Update on the role of cardiac magnetic resonance in acquired on ischemic cardiomyopathies. J Thorac Imaging 31(6):348–366CrossRefPubMed
52.
go back to reference Murphy CJ, Oudit GY (2010) Iron-overload cardiomyopathy: pathophysiology, diagnosis, and treatment. J Card Fail 16(11):888–900CrossRefPubMed Murphy CJ, Oudit GY (2010) Iron-overload cardiomyopathy: pathophysiology, diagnosis, and treatment. J Card Fail 16(11):888–900CrossRefPubMed
53.
go back to reference Kremastinos DT, Farmakis D (2011) Iron overload cardiomyopathy in clinical practice. Circulation 124:2253–2263CrossRefPubMed Kremastinos DT, Farmakis D (2011) Iron overload cardiomyopathy in clinical practice. Circulation 124:2253–2263CrossRefPubMed
54.
go back to reference Anderson LJ, Holden S, Davis B et al (2001) Cardiovascular T2 star magnetic resonance for the early diagnosis of myocardial iron overload. Eur Heart J 22(23):2171–2179CrossRefPubMed Anderson LJ, Holden S, Davis B et al (2001) Cardiovascular T2 star magnetic resonance for the early diagnosis of myocardial iron overload. Eur Heart J 22(23):2171–2179CrossRefPubMed
55.
go back to reference Vignaux O (2005) Cardiac sarcoidosis: spectrum of MRI features. Am J Roentgenol 194:249–254CrossRef Vignaux O (2005) Cardiac sarcoidosis: spectrum of MRI features. Am J Roentgenol 194:249–254CrossRef
56.
go back to reference Turkbey EB, McClelland RL, Kronmal RA et al (2010) The impact of obesity on the left ventricle. The Multi-Ethnic Study of Atherosclerosis (MESA). JACC Cardiovasc Imaging 3(3):266–274CrossRefPubMedPubMedCentral Turkbey EB, McClelland RL, Kronmal RA et al (2010) The impact of obesity on the left ventricle. The Multi-Ethnic Study of Atherosclerosis (MESA). JACC Cardiovasc Imaging 3(3):266–274CrossRefPubMedPubMedCentral
57.
go back to reference Eguchi K, Boden-Albala B, Jin Z et al (2008) Association between diabetes mellitus and left ventricular hypertrophy in a multi-ethnic population. Am J Cardiol 101(12):1787–1791CrossRefPubMedPubMedCentral Eguchi K, Boden-Albala B, Jin Z et al (2008) Association between diabetes mellitus and left ventricular hypertrophy in a multi-ethnic population. Am J Cardiol 101(12):1787–1791CrossRefPubMedPubMedCentral
58.
go back to reference Harrigan CJ, Appelbaum E, Maron BJ et al (2008) Significance of papillary muscle abnormalities identified by cardiovascular magnetic resonance in hypertrophic cardiomyopathy. Am J Cardiol 101(5):668–673CrossRefPubMed Harrigan CJ, Appelbaum E, Maron BJ et al (2008) Significance of papillary muscle abnormalities identified by cardiovascular magnetic resonance in hypertrophic cardiomyopathy. Am J Cardiol 101(5):668–673CrossRefPubMed
59.
go back to reference Maron M, Olivotto I, Harrigan C et al (2011) Mitral valve abnormalities identified by cardiovascular magnetic resonance represent a primary phenotypic expression of hypertrophic cardiomyopathy. Circulation 124(1):40–47CrossRefPubMed Maron M, Olivotto I, Harrigan C et al (2011) Mitral valve abnormalities identified by cardiovascular magnetic resonance represent a primary phenotypic expression of hypertrophic cardiomyopathy. Circulation 124(1):40–47CrossRefPubMed
60.
go back to reference Rubinshtein R, Glockner JF, Ommen SR et al (2010) Characteristics and clinical significance of late gadolinium enhancement by contrast-enhanced magnetic resonance imaging in patients with hypertrophic cardiomyopathy. Circ Heart Fail 3(1):51–58CrossRefPubMed Rubinshtein R, Glockner JF, Ommen SR et al (2010) Characteristics and clinical significance of late gadolinium enhancement by contrast-enhanced magnetic resonance imaging in patients with hypertrophic cardiomyopathy. Circ Heart Fail 3(1):51–58CrossRefPubMed
61.
go back to reference O’Hanlon R, Grasso A, Roughton M et al (2010) Prognostic significance of myocardial fibrosis in hypertrophic cardiomyopathy. J Am Coll Cardiol 56(11):867–874CrossRefPubMed O’Hanlon R, Grasso A, Roughton M et al (2010) Prognostic significance of myocardial fibrosis in hypertrophic cardiomyopathy. J Am Coll Cardiol 56(11):867–874CrossRefPubMed
62.
go back to reference Bruder O, Wagner A, Jensen CJ et al (2010) Myocardial scar visualized by cardiovascular magnetic resonance imaging predicts major adverse events in patients with hypertrophic cardiomyopathy. J Am Coll Cardiol 56(11):875–887CrossRefPubMed Bruder O, Wagner A, Jensen CJ et al (2010) Myocardial scar visualized by cardiovascular magnetic resonance imaging predicts major adverse events in patients with hypertrophic cardiomyopathy. J Am Coll Cardiol 56(11):875–887CrossRefPubMed
63.
go back to reference Ellims AH, Iles LM, Ling LH et al (2012) Diffuse myocardial fibrosis in hypertrophic cardiomyopathy can be identified by cardiovascular magnetic resonance, and is associated with left ventricular diastolic dysfunction. J Cardiovasc Magn Reson 14:76CrossRefPubMedPubMedCentral Ellims AH, Iles LM, Ling LH et al (2012) Diffuse myocardial fibrosis in hypertrophic cardiomyopathy can be identified by cardiovascular magnetic resonance, and is associated with left ventricular diastolic dysfunction. J Cardiovasc Magn Reson 14:76CrossRefPubMedPubMedCentral
64.
go back to reference Pelliccia A, Maron BJ, Spataro A, Proschan MA, Spirito P (1991) The upper limit of physiologic cardiac hypertrophy in highly trained elite athletes. N Engl J Med 324(5):295–301CrossRefPubMed Pelliccia A, Maron BJ, Spataro A, Proschan MA, Spirito P (1991) The upper limit of physiologic cardiac hypertrophy in highly trained elite athletes. N Engl J Med 324(5):295–301CrossRefPubMed
65.
go back to reference Fagard R (2012) Athlete’s heart or hypertrophic cardiomyopathy. Heart Metab 56:14–19 Fagard R (2012) Athlete’s heart or hypertrophic cardiomyopathy. Heart Metab 56:14–19
66.
go back to reference Petersen SE, Selvanayagam JB, Francis JM et al (2005) Differentiation of athlete’s heart from pathological forms of cardiac hypertrophy by means of geometric indices derived from cardiovascular magnetic resonance. J Cardiovasc Magn Reson 7(3):551–558CrossRefPubMed Petersen SE, Selvanayagam JB, Francis JM et al (2005) Differentiation of athlete’s heart from pathological forms of cardiac hypertrophy by means of geometric indices derived from cardiovascular magnetic resonance. J Cardiovasc Magn Reson 7(3):551–558CrossRefPubMed
67.
go back to reference Breuckmann F, Möhlenkamp S, Nassenstein K et al (2009) Myocardial late gadolinium enhancement: prevalence, pattern, and prognostic relevance in marathon runners. Radiology 251(1):50–57CrossRefPubMed Breuckmann F, Möhlenkamp S, Nassenstein K et al (2009) Myocardial late gadolinium enhancement: prevalence, pattern, and prognostic relevance in marathon runners. Radiology 251(1):50–57CrossRefPubMed
68.
go back to reference Van de Schoor FR, Aengevaeren VL, Hopman MTE (2016) Myocardial fibrosis in athletes. Mayo Clin Proc 91(11):1617–1631CrossRefPubMed Van de Schoor FR, Aengevaeren VL, Hopman MTE (2016) Myocardial fibrosis in athletes. Mayo Clin Proc 91(11):1617–1631CrossRefPubMed
69.
go back to reference Chalabreysse L, Berger F, Loire R, Devouassoux G, Cordier J-F, Thivolet-Bejui F (2002) Primary cardiac lymphoma in immunocompetent patients: a report of three cases and review of the literature. Virchows Arch 441:456–461CrossRefPubMed Chalabreysse L, Berger F, Loire R, Devouassoux G, Cordier J-F, Thivolet-Bejui F (2002) Primary cardiac lymphoma in immunocompetent patients: a report of three cases and review of the literature. Virchows Arch 441:456–461CrossRefPubMed
70.
go back to reference Mateen FJ, Harding SR, Saxena A (2006) Extensive myocardial infiltration by hemopoietic precursors in a patient with myelodysplastic syndrome. BMC Blood Disord 6:4PubMedPubMedCentral Mateen FJ, Harding SR, Saxena A (2006) Extensive myocardial infiltration by hemopoietic precursors in a patient with myelodysplastic syndrome. BMC Blood Disord 6:4PubMedPubMedCentral
Metadata
Title
Utility of magnetic resonance imaging in the evaluation of left ventricular thickening
Authors
Nicholas Fulton
Prabhakar Rajiah
Publication date
01-04-2017
Publisher
Springer Berlin Heidelberg
Published in
Insights into Imaging / Issue 2/2017
Electronic ISSN: 1869-4101
DOI
https://doi.org/10.1007/s13244-017-0549-2

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