Published in:
01-06-2021 | Cardiomyopathy | EDITORIAL
Parameters of left ventricular systolic and diastolic dyssynchrony on radionuclide imaging to improve cardiac resynchronization therapy in heart failure patients with dilated cardiomyopathy
Authors:
Jayakumar Sreenivasan, MD, MSc, Diwakar Jain, MD, FACC, MASNC
Published in:
Journal of Nuclear Cardiology
|
Issue 3/2021
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Excerpt
Cardiac resynchronization therapy (CRT) is a proven therapeutic intervention for selected patients with heart failure with reduced ejection fraction and electrical conduction delay.
1 However, studies have shown that at least one-third of patients who undergo CRT based on currently recommended indications experience no significant improvement.
2 Patient selection still remains a challenge despite multiple studies that have investigated predictors of favorable outcomes following CRT.
3,
4 Narrower baseline QRS duration, suboptimal left ventricular (LV) lead placement, larger myocardial scar burden, and ischemic cardiomyopathy are a few factors associated with poor response to CRT.
3‐
5 Multiple different parameters of LV mechanical dyssynchrony have been of recent interest to predict outcomes following CRT.
6,
7 …
