Time-of-flight in cardiac PET/TC: What do we know and what we should know?

Excerpt

Coronary arteries disease (CAD) is the most common cause of death in the world, and an accurate diagnosis can be made by combining the diagnostic results of different invasive and noninvasive techniques. Among the latter, molecular imaging has gained growing importance, and above all, positron emission tomography (PET), combined with computed tomography (CT), has shown increasing diagnostic accuracy in detecting small and low perfusion areas in the myocardial wall.1 This was possible thanks to the cardiac-dedicated PET radiotracers (for example, Rubidium-82 chloride, ⁸²Rb), but also to the last generation of correction techniques available for the acquisition of the emission data and in the reconstruction process of myocardial images. …