Published in:
01-08-2018 | Editorial
Optimizing myocardial metabolism for fluorine-18 fluorodeoxyglucose positron emission tomography imaging of cardiac inflammation
Authors:
Efstathia Andrikopoulou, MD, Pradeep Bhambhvani, MD
Published in:
Journal of Nuclear Cardiology
|
Issue 4/2018
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Excerpt
Inflammation-related hot spot imaging along with suppression of physiologic myocardial glucose metabolism forms the basis of fluorine-18 fluorodeoxyglucose positron emission tomography (FDG-PET) imaging of inflammatory cardiomyopathies, infections of intracardiac devices, and prosthetic valves and vulnerable coronary plaques. Adequate attenuation of physiologic myocardial glucose uptake that ensures high-quality FDG-PET images, however, can be challenging, especially since glucose can be physiologically taken up by the cardiomyocytes under certain conditions. In order to maximize suppression of normal glucose uptake, a number of different interventions have been proposed and are utilized by PET laboratories, without there being a consensus on the most effective one. …