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Clinical Journal of Gastroenterology
Published in: Clinical Journal of Gastroenterology 4/2019

01-08-2019 | Endoscopic Retrograde Pancreatography | Case Report

Surgically resected pancreatic metastasis from nasal malignant melanoma: case report and literature review

Authors: Yoshihide Kanno, Yutaka Noda, Shinsuke Koshita, Takahisa Ogawa, Kaori Masu, Masaya Oikawa, Takaho Okada, Naoya Akazawa, Takashi Sawai, Kei Ito

Published in: Clinical Journal of Gastroenterology | Issue 4/2019

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Abstract

A 13-mm mass was observed in the pancreatic head of a 70-year-old woman who had undergone melanoma resection in the nasal cavity 10 years earlier. Endoscopic ultrasonography (EUS) showed that the mass consisted of multiple hypoechoic nodules. EUS-guided fine needle aspiration and pancreatic juice cytologies revealed neoplastic cells positive for HMB45 and melan-A staining with a few melanin granules, indicating the presence of a metastatic malignant melanoma. These additional stainings were evaluated after surgery. In the surgically resected specimen, the mass had multiple nodule-like structures, some of which were brown colored. Immunocytochemistry and electronic microscopy findings confirmed the diagnosis of malignant melanoma. Microscopic findings were similar to the nasal specimen; therefore, the pancreatic lesion was considered to be a metastasis from the nasal cavity.
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Metadata
Title
Surgically resected pancreatic metastasis from nasal malignant melanoma: case report and literature review
Authors
Yoshihide Kanno
Yutaka Noda
Shinsuke Koshita
Takahisa Ogawa
Kaori Masu
Masaya Oikawa
Takaho Okada
Naoya Akazawa
Takashi Sawai
Kei Ito
Publication date
01-08-2019
Publisher
Springer Japan
Published in
Clinical Journal of Gastroenterology / Issue 4/2019
Print ISSN: 1865-7257
Electronic ISSN: 1865-7265
DOI
https://doi.org/10.1007/s12328-019-00936-4

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