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Radiological Physics and Technology
Published in: Radiological Physics and Technology 1/2020

01-03-2020 | Computed Tomography

Transbronchial biopsy of peripheral lung lesions using fluoroscopic guidance combined with an enhanced ray-summation display

Authors: Shogo Suzuki, Katsuhiro Ichikawa, Yasuhisa Kouno, Naoya Takeda, Yoshihiro Suzuki, Ayumi Suzuki

Published in: Radiological Physics and Technology | Issue 1/2020

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Abstract

The aim of this study was to investigate the effectiveness of guidance assistance during transbronchial biopsy (TBB) to achieve an appropriate pathway to small and peripheral pulmonary lesions (PPLs) using a combination of fluoroscopy and specialized ray-summation (Ray-sumTBB) images, which were processed from preprocedural lung computed tomography (CT) images. To improve the visibility of the correct pathway to the PPLs, three-dimensional spatial resolution enhancement and CT number conversion processes were applied to the original CT images. The Ray-sumTBB images reconstructed from the processed CT images were used as additional guides. We compared the rates of successful tumor localization and biopsy (arrival rate) between the trial (with Ray-sumTBB) and control (without Ray-sumTBB) groups. The fluoroscopy and examination times were also compared. The arrival rate of the trial group (73.1%) was significantly better than that of the control group (42.3%) (p = 0.048). The fluoroscopy and examination times did not differ significantly between the trial and control groups. No complications were identified in the trial group. Our results suggest that Ray-sumTBB improves the diagnostic accuracy of TBB.
Literature
1.
Eberhardt R, Anantham D, Ernst A, Feller-Kopman D, Herth F. Multimodality bronchoscopic diagnosis of peripheral lung lesions: a randomized controlled trial. Am J Respir Crit Care Med. 2007;176:36–41.CrossRef
2.
Wang Memoli JS, Nietert PJ, Silvestri GA. Meta-analysis of guided bronchoscopy for the evaluation of the pulmonary nodule. Chest. 2012;142:385–93.CrossRef
3.
Rivera MP, Mehta AC. Initial diagnosis of lung cancer: ACCP evidence-based clinical practice guidelines. Chest. 2007;132:131S–48S.CrossRef
4.
Gould MK, Donington J, Lynch WR, Mazzone PJ, Midthun DE, Naidich DP, Wiener RS. Evaluation of individuals with pulmonary nodules: when is it lung cancer? Diagnosis and management of lung cancer, 3rd ed: American College of Chest Physicians evidence-based clinical practice guidelines. Chest. 2013;143:e93S–e120S.CrossRef
5.
Herth FJ, Eberhardt R, Becker HD, Ernst A. Endobronchial ultrasound-guided transbronchial lung biopsy in fluoroscopically invisible solitary pulmonary nodules: a prospective trial. Chest. 2006;129:147–50.CrossRef
6.
Eberhardt R, Anantham D, Herth F, Feller-Kopman D, Ernst A. Electromagnetic navigation diagnostic bronchoscopy in peripheral lung lesions. Chest. 2007;131:1800–5.CrossRef
7.
Kikuchi E, Yamazaki K, Sukoh N, Kikuchi J, Asahina H, Imura M, Nishimura M. Endobronchial ultrasonography with guide-sheath for peripheral pulmonary lesions. Eur Respir J. 2004;24:533–7.CrossRef
8.
Yamada N, Yamazaki K, Kurimoto N, Asahina H, Kikuchi E, Shinagawa N, Oizumi S, Nishimura M. Factors related to diagnostic yield of transbronchial biopsy using endobronchial ultrasonography with a guide sheath in small peripheral pulmonary lesions. Chest. 2007;132:603–8.CrossRef
9.
Ong PG, Debiane LG, Casal RF. Recent advances in diagnostic bronchoscopy. J Thorac Dis. 2016;8:3808–17.CrossRef
10.
Endo M, Kotani Y, Satouchi M, Takada Y, Sakamoto T, Tsubota N, Furukawa H. CT fluoroscopy-guided bronchoscopic dye marking for resection of small peripheral pulmonary nodules. Chest. 2004;125:1747–52.CrossRef
11.
Ost D, Shah R, Anasco E, Lusardi L, Doyle J, Austin C, Fein A. A randomized trial of CT fluoroscopic-guided bronchoscopy vs conventional bronchoscopy in patients with suspected lung cancer. Chest. 2008;134:507–13.CrossRef
12.
Asahina H, Yamazaki K, Onodera Y, Kikuchi E, Shinagawa N, Asano F, Nishimura M. Transbronchial biopsy using endobronchial ultrasonography with a guide sheath and virtual bronchoscopic navigation. Chest. 2005;128:1761–5.CrossRef
13.
Asano F, Matsuno Y, Shinagawa N, Yamazaki K, Suzuki T, Ishida T, Moriya H. A virtual bronchoscopic navigation system for pulmonary peripheral lesions. Chest. 2006;130:559–66.CrossRef
14.
Ishida T, Asano F, Yamazaki K, Shinagawa N, Oizumi S, Moriya H, Nunakata M, Nishimura M. Virtual bronchoscopic navigation combined with endobronchial ultrasound to diagnose small peripheral pulmonary lesions: a randomised trial. Thorax. 2011;66:1072–7.CrossRef
15.
Merritt SA, Gibbs JD, Yu KC, Patel V, Rai L, Cornish DC, Bascom R, Higgins WE. Image-guided bronchoscopy for peripheral lung lesions: a phantom study. Chest. 2008;134:1017–26.CrossRef
16.
Sterman DH, Keast T, Rai L, Gibbs J, Wibowo H, Draper J, Herth FJ, Silvestri GA. High yield of bronchoscopic transparenchymal nodule access real-time image-guided sampling in a novel model of small pulmonary nodules in canines. Chest. 2015;147:700–7.CrossRef
17.
Silvestri GA, Herth FJ, Keast T, Rai L, Gibbs J, Wibowo H, Sterman DH. Feasibility and safety of bronchoscopic transparenchymal nodule access in canines: a new real-time image-guided approach to lung lesions. Chest. 2014;145:833–8.CrossRef
18.
Schwarz Y, Greif J, Becker HD, Ernst A, Mehta A. Real-time electromagnetic navigation bronchoscopy to peripheral lung lesions using overlaid CT images: the first human study. Chest. 2006;129:988–94.CrossRef
19.
Shinagawa N, Yamazaki K, Onodera Y, Miyasaka K, Kikuchi E, Dosaka-Akita H, Nishimura M. CT-guided transbronchial biopsy using an ultrathin bronchoscope with virtual bronchoscopic navigation. Chest. 2004;125:1138–43.CrossRef
20.
Edell E, Krier-Morrow D. Navigational bronchoscopy: overview of technology and practical considerations—new current procedural terminology codes effective 2010. Chest. 2010;137:450–4.CrossRef
21.
Ichikawa K, Kobayashi T, Sagawa M, Katagiri A, Uno Y, Nishioka R, Matsuyama J. A phantom study investigating the relationship between ground-glass opacity visibility and physical detectability index in low-dose chest computed tomography. J Appl Clin Med Phys. 2015;16:202–15.CrossRef
22.
Rose A. The sensitivity performance of the human eye on an absolute scale. J Opt Soc Am. 1948;38:196–208.CrossRef
23.
Yoshikawa M, Sukoh N, Yamazaki K, Kanazawa K, Fukumoto S, Harada M, Kikuchi E, Munakata M, Nishimura M, Isobe H. Diagnostic value of endobronchial ultrasonography with a guide sheath for peripheral pulmonary lesions without X-ray fluoroscopy. Chest. 2007;131:1788–93.CrossRef
24.
Kurimoto N, Miyazawa T, Okimasa S, Maeda A, Oiwa H, Miyazu Y, Murayama M. Endobronchial ultrasonography using a guide sheath increases the ability to diagnose peripheral pulmonary lesions endoscopically. Chest. 2004;126:959–65.CrossRef
25.
Ichikawa K, Kodera Y, Ohashi K, Sugiyama M, Miyachi T, Fujita H. Performance evaluation of computed tomography with equivalent resolution images. Nihon Hoshasen Gijutsu Gakkai Zasshi. 2006;62:522–8.CrossRef
26.
Suzuki S, Ichikawa K, Tamaki S. Image quality and clinical usefulness of ray-summation image reconstructed from CT data, compared with digital radiography. Nihon Hoshasen Gijutsu Gakkai Zasshi. 2017;73:372–81.CrossRef
27.
Onodera Y, Omatsu T, Takeuchi S, Shinagawa N, Yamazaki K, Nishioka T, Miyasaka K. Enhanced virtual bronchoscopy using the pulmonary artery: improvement in route mapping for ultraselective transbronchial lung biopsy. AJR Am J Roentgenol. 2004;183:1103–10.CrossRef
28.
Oki M, Saka H, Ando M, Asano F, Kurimoto N, Morita K, Kitagawa C, Kogure Y, Miyazawa T. Ultrathin bronchoscopy with multimodal devices for peripheral pulmonary lesions. A randomized trial. Am J Respir Crit Care Med. 2015;192:468–76.CrossRef
29.
Asano F, Shinagawa N, Ishida T, Shindoh J, Anzai M, Tsuzuku A, Oizumi S, Morita S. Virtual bronchoscopic navigation combined with ultrathin bronchoscopy. A randomized clinical trial. Am J Respir Crit Care Med. 2013;188:327–33.CrossRef
30.
Chen A, Pastis N, Furukawa B, Silvestri GA. The effect of respiratory motion on pulmonary nodule location during electromagnetic navigation bronchoscopy. Chest. 2015;147:1275–81.CrossRef
Metadata
Title
Transbronchial biopsy of peripheral lung lesions using fluoroscopic guidance combined with an enhanced ray-summation display
Authors
Shogo Suzuki
Katsuhiro Ichikawa
Yasuhisa Kouno
Naoya Takeda
Yoshihiro Suzuki
Ayumi Suzuki
Publication date
01-03-2020
Publisher
Springer Singapore
Published in
Radiological Physics and Technology / Issue 1/2020
Print ISSN: 1865-0333
Electronic ISSN: 1865-0341
DOI
https://doi.org/10.1007/s12194-019-00546-2

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