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Head and Neck Pathology
Published in: Head and Neck Pathology 1/2022

01-03-2022 | Leukoplakia | UPDATE FROM THE 5TH EDITION OF THE WORLD HEALTH ORGANIZATION CLASSIFICATION OF HEAD AND NECK TUMORS

Update from the 5th Edition of the World Health Organization Classification of Head and Neck Tumors: Tumours of the Oral Cavity and Mobile Tongue

Authors: Susan Muller, Wanninayake M. Tilakaratne

Published in: Head and Neck Pathology | Issue 1/2022

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Abstract

The fifth chapter of the upcoming fifth edition of the 2022 World Health Organization Classification of Tumours of the Head and Neck titled Tumours of the oral cavity and mobile tongue, has had some modifications from the 2017 fourth edition. A new section "Non-neoplastic Lesions", introduces two new entries: necrotizing sialometaplasia and melanoacanthoma. The combined Oral potentially malignant disorders and Oral epithelial dysplasia section in the 2015 WHO has now been separated and submucous fibrosis and HPV-associated dysplasia are also discussed in separate sections. Carcinoma cuniculatum and verrucous carcinoma are described in dedicated sections, reflecting that the oral cavity is the most common location in the head and neck for both these entities which have distinct clinical and histologic features from conventional squamous cell carcinoma. This review summarizes the changes in Chapter 5 with special reference to new additions, deletions, and sections that reflect current clinical, histological, and molecular advances.
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Metadata
Title
Update from the 5th Edition of the World Health Organization Classification of Head and Neck Tumors: Tumours of the Oral Cavity and Mobile Tongue
Authors
Susan Muller
Wanninayake M. Tilakaratne
Publication date
01-03-2022
Publisher
Springer US
Published in
Head and Neck Pathology / Issue 1/2022
Electronic ISSN: 1936-0568
DOI
https://doi.org/10.1007/s12105-021-01402-9

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