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Head and Neck Pathology
Published in: Head and Neck Pathology 1/2022

01-03-2022 | Rhabdomyosarcoma | Proceeding of the North American Society of Head and Neck Pathology Companion Meeting, March 20, 2022, Los Angeles, CA

Proceedings of the North American Society of Head and Neck Pathology, Los Angeles, CA, March 20, 2022. Emerging Bone and Soft Tissue Neoplasms in the Head and Neck Region

Author: Bin Xu

Published in: Head and Neck Pathology | Issue 1/2022

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Abstract

In the past decade, several emerging bone and soft tissue neoplasms of the head and neck region have been described in the literature, including GLI1-altered mesenchymal tumors, (intraosseous) rhabdomyosarcoma with TFCP2 fusion, and adamantinoma-like Ewing sarcoma. This review provides a summary of the clinical features, histologic characteristics, immunoprofile, key diagnostic features, and differential diagnoses of these emerging entities. Notably, all three entities show epithelioid morphology and cytokeratin immunopositivity, highlighting the need to consider these mesenchymal neoplasms in the differential diagnoses of cytokeratin-positive epithelioid tumors in the head and neck region. Appropriate workups including detection of the characteristic molecular alterations are essential for the correct diagnosis.
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Metadata
Title
Proceedings of the North American Society of Head and Neck Pathology, Los Angeles, CA, March 20, 2022. Emerging Bone and Soft Tissue Neoplasms in the Head and Neck Region
Author
Bin Xu
Publication date
01-03-2022
Publisher
Springer US
Published in
Head and Neck Pathology / Issue 1/2022
Electronic ISSN: 1936-0568
DOI
https://doi.org/10.1007/s12105-022-01418-9

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