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2506 search results for:

Lichen Planus 

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  1. Open Access 01-12-2024 | OriginalPaper

    The effect of antiresorptive therapy on the prevalence and severity of oral lichen planus: a retrospective study

    Antiresorptive (AR) drugs, including bisphosphonates (BP), estrogen modulators and, bone remodeling-targeted monoclonal antibodies, such as denosumab, are prescribed for the treatment of different skeletal disorders characterized by abnormal bone …

  2. Open Access 01-12-2024 | Lichen Planus | OriginalPaper

    Post-radiation lichen planus: a case report and review of the literature

    This is a patient who presented with lichen planus, a rare adverse effect from external beam radiation. Between 2002 and 2017, only 12 cases were reported in the medical literature [ 1 ]. Because of its low incidence, providers should be informed …

  3. 11-12-2023 | Lichen Planus | OriginalPaper

    Histologic and Histomorphometric Comparative Study of Oral Lichen Planus Versus Oral Lichenoid Reaction

    Oral lichen planus (OLP) is a T-cell-mediated chronic inflammatory disease of the oral mucosa clinically manifested with white reticular lesions sometimes accompanied by atrophic and erosive lesions and less frequently by papular, plaque-like, or …

  4. Open Access 01-12-2024 | Cytokines | OriginalPaper

    Inflammatory cytokines mediating the effect of oral lichen planus on oral cavity cancer risk: a univariable and multivariable mendelian randomization study

    Head and neck squamous cell carcinoma (HNSCC), is recognized worldwide as the sixth most prevalent malignancy, has its larger subgroup in oral cavity cancer (OCC) [ 1 , 2 ]. Despite the progress in treating OCC in recent years, the overall 5-year …

  5. Open Access 01-12-2024 | Lichen Planus | OriginalPaper

    Immunophenotypic and Gene Expression Analyses of the Inflammatory Microenvironment in High-Grade Oral Epithelial Dysplasia and Oral Lichen Planus

    Oral lichen planus (OLP) is a chronic inflammatory condition frequently affecting the oral cavity. Although multiple agents have been previously associated with OLP, no specific etiology is currently described as the cause. The persistent issue in …

  6. Open Access 01-12-2024 | Lichen Planus | OriginalPaper

    Evaluation of the association between TNF-α-1031 T/C polymorphism with oral lichen planus disease

    Lichen planus is a common chronic inflammatory mucosal and skin disorder that affects approximately 0.5–4% of the worldwide population, with a malignant transformation rate of 1.4% [ 1 , 2 ]. Also, OLP had a higher prevalence among middle-aged …

  7. Open Access 01-12-2024 | Lichen Planus | OriginalPaper

    Photobiomodulation versus corticosteroid in the management of erosive oral lichen planus: a randomized controlled clinical trial

    Oral lichen planus (OLP) is an inflammatory mucocutaneous disease of chronic nature that affects 1%–2% of middle-aged individuals, with a distinct female prevalence [ 1 , 2 ]. It typically manifests as bilateral, symmetrical lesions, mostly …

  8. Open Access 01-04-2024 | Lichen Planus | OriginalPaper

    Assessment of PD-1 and PD-L1 tissue expression levels in lichen planus patients: a case–control study

    Programmed cell death protein-1 (PD-1) is an immune checkpoint protein, PD-1 interaction with PD ligand-1 (PD-L1) is essential for maintaining immunological tolerance. The study aimed to study and compare the levels of PD-1 and PD-L1 in lesional …

  9. Open Access 01-12-2024 | Methotrexate | OriginalPaper

    The efficacy and safety of deucravacitinib compared to methotrexate, in patients with vulvar lichen planus who have failed topical therapy with potent corticosteroids: a study protocol for a single-centre double-blinded randomised controlled trial

    Note: the numbers in curly brackets in this protocol refer to the SPIRIT checklist item numbers. The order of the items has been modified to group similar items (see …

  10. Open Access 01-12-2024 | Lichen Planus | OriginalPaper

    Effects of Curcumin on the treatment of oral lichen planus symptoms: a systematic review and meta-analysis study

    Oral lichen planus (OLP) is a chronic inflammatory disease with lesions of varying severity and appearance. Its prevalence is about 0.5–2% [ 1 ]. The highest incidence of the disease is in the middle-aged population, with a female predominance with …

  11. Open Access 01-01-2024 | Lichen Planus | OriginalPaper

    Salivary metabolomics in patients with oral lichen planus: a preliminary study based on NMR spectroscopy

    Oral lichen planus (OLP) is a chronic immune-mediated inflammatory disease affecting oral mucosa with characteristic relapses and remissions [ 1 ]. OLP is a potentially precancerous condition, defined as a generalized state associated with a …

  12. Open Access 01-12-2024 | Lichen Planus | OriginalPaper

    Inter-relationships of galectin-3 and NLR family pyrin domain containing 3 inflammasomes with oral lichen planus: a preliminary cross-sectional in vitro study

    Oral lichen planus (OLP) stands as an immune-mediated chronic inflammatory disease, manifesting through reticulated, linear, and dendritic white markings formed by small papules, often accompanied by congestion, erosion, ulcers, atrophy, and …

  13. 15-09-2023 | Lichen Planus | ReviewPaper

    Oral Lichen Planus: An Update on Diagnosis and Management

    Oral lichen planus (OLP) is a chronic inflammatory disease whose pathogenesis involves a T-cell mediated, epithelium-directed inflammation in response to unknown antigen(s). The disease evolves by intermittent flares and displays polymorphous …

  14. 30-12-2023 | Lichen Planus | Online First

    MALT1 Protease Regulates T-Cell Immunity via the mTOR Pathway in Oral Lichen Planus

    Oral lichen planus (OLP) is a T cell–mediated immune mucosal disease of unknown pathogenesis. Whether mucosa-associated lymphoid tissue lymphoma translocation protein 1 (MALT1), an intracellular signaling protein, is involved in the T-cell immune …

  15. 11-11-2023 | Lichen Planus | Online First

    Lichen planus—A rare cause for dysphagia

  16. Open Access 01-01-2024 | Lichen Planus | OriginalPaper

    Patients with oral lichen planus display lower levels of salivary acidic glycoproteins than individuals without oral mucosal disease

    Glycoproteins are rich in negatively charged groups of sialic acids and sulfate residues that contribute to the rheological properties of the saliva [ 1 , 2 ]. Mucins are large glycoproteins and may contain one or more negatively charged sialic …

  17. 03-11-2023 | Lichen Planus | ReviewPaper

    Systemic non-steroidal immunomodulators for oral lichen planus treatment—a scoping review

    Lichen planus (LP) is a chronic mucocutaneous inflammatory disease. LP can result in oral lesions, which usually precede skin lesions and, in many cases, are the only clinical manifestation. When oral lesions occur, it is classified as oral lichen

  18. 01-01-2024 | Lichen Planus | OriginalPaper

    The impact of COVID-19 pandemic in patients with a diagnosis of Oral Lichen Planus: Pain perception and psychological profile analysis

    The oral lichen planus (OLP) is a chronic inflammatory non-infectious disease which involves the stratified squamous epithelium of the oral mucosa and the lamina propria underneath (Adamo et al. [ 1 ]). It is considered a precursor of the squamous …

  19. Open Access 01-12-2023 | Lichen Planus | OriginalPaper

    Senescence-associated secretory phenotypes in mesenchymal cells contribute to cytotoxic immune response in oral lichen planus

    Oral lichen planus is a chronic inflammatory condition that adversely affects the oral mucosa; however, its etiology remains elusive. Consequently, therapeutic interventions for oral lichen planus are limited to symptomatic management. This study …

  20. Open Access 01-12-2023 | Lichen Planus | OriginalPaper

    Single session of laser photobiomodulation for symptom management of oral lichen planus: a retrospective study

    This study aimed to evaluate the effectiveness of a single session of laser photobiomodulation (PBM) with flat top handpiece in reducing painful symptoms in patients with Oral Lichen Planus (OLP). The clinical charts of 20 patients of the Dental …

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