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Published in:

01-12-2017

Immunoglobulin G4 (IgG4)-Related Hypophysitis

Authors: Fabio Rotondo, Amro Qaddoura, Luis V. Syro, Jason Karamchandani, David G. Munoz, Mariam J. Arroyave, William P. Ospina, Michael D. Cusimano, Kalman Kovacs

Published in: Endocrine Pathology | Issue 4/2017

Abstract

We report two different cases of IgG4-related hypophysitis. In the first case, a pituitary lesion was accompanied by lymphocytic meningitis possibly mimicking tuberculous meningitis. The second case was unassociated with involvement of other organs. No histologic differences were noted between the two cases indicating that the morphologic features of the hypophysial lesion do not depend on the presence of other lesions. The pathogenesis of IgG4 hypophysitis is not known, and further study is necessary to explore the cause, progression, and influencing factors of this disease.

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Title: Immunoglobulin G4 (IgG4)-Related Hypophysitis
Authors: Fabio Rotondo
Amro Qaddoura
Luis V. Syro
Jason Karamchandani
David G. Munoz
Mariam J. Arroyave
William P. Ospina
Michael D. Cusimano
Kalman Kovacs
Publication date: 01-12-2017
Publisher: Springer US
Published in: Endocrine Pathology / Issue 4/2017
Print ISSN: 1046-3976
Electronic ISSN: 1559-0097
DOI: https://doi.org/10.1007/s12022-016-9464-1

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