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Clinical Rheumatology
Published in: Clinical Rheumatology 9/2013

01-09-2013 | Review Article

The great mimicker: IgG4-related disease

Authors: Rodolfo Perez Alamino, Luis R. Espinoza, Arnold H. Zea

Published in: Clinical Rheumatology | Issue 9/2013

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Abstract

IgG4-related disease is defined as a multi-organ systemic disorder with pathological findings affecting a wide range of organ systems. The condition unifies a large number of clinical diagnoses previously considered as being confined to single organ systems. At present, several issues related to its pathophysiology remained controversial, including the natural history of the disease, the pathogenic role of IgG4, and its use as a biomarker. Glucocorticoids are considered the treatment of choice for remission induction of IgG4-related disease manifestations; however, concerns regarding duration of therapy and management of refractory disease remained to be elucidated.
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Metadata
Title
The great mimicker: IgG4-related disease
Authors
Rodolfo Perez Alamino
Luis R. Espinoza
Arnold H. Zea
Publication date
01-09-2013
Publisher
Springer London
Published in
Clinical Rheumatology / Issue 9/2013
Print ISSN: 0770-3198
Electronic ISSN: 1434-9949
DOI
https://doi.org/10.1007/s10067-013-2326-z

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