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Published in:

01-06-2009

MicroRNA Expression Profiles in Thyroid Tumors

Authors: Marina N. Nikiforova, Simon I. Chiosea, Yuri E. Nikiforov

Published in: Endocrine Pathology | Issue 2/2009

Abstract

MicroRNAs (miRNAs) constitute a recently identified class of small endogenous noncoding RNAs that act as negative regulators of the protein-coding gene expression and may impact cell differentiation, proliferation and survival, i.e., all fundamental cellular processes implicated in carcinogenesis. miRNA expression is deregulated in many types of human cancers, including thyroid cancer. The purpose of this review is to summarize the existing findings of miRNA deregulation in thyroid tumors and its potential role in thyroid cancer biology and molecular diagnostics.

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Title: MicroRNA Expression Profiles in Thyroid Tumors
Authors: Marina N. Nikiforova
Simon I. Chiosea
Yuri E. Nikiforov
Publication date: 01-06-2009
Publisher: Humana Press Inc
Published in: Endocrine Pathology / Issue 2/2009
Print ISSN: 1046-3976
Electronic ISSN: 1559-0097
DOI: https://doi.org/10.1007/s12022-009-9069-z

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