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Published in: Obesity Surgery 5/2020

01-05-2020 | Obesity | Letter to the Editor

Cardia Gastric Cancer in the Gastric Pouch 5 Years after Gastric Bypass: A Case Report

Authors: Wenhui Chen, Guanghui Zhang, Zhiyong Dong, LokWan Liu, Yucheng Wang, Xiaomei Chen, Jinfeng Zhang, Cunchuan Wang

Published in: Obesity Surgery | Issue 5/2020

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Abstract

Background

Roux-en-Y gastric bypass (RYGB) is one of the most frequently performed bariatric procedures worldwide. Remnant gastric cancer after RYGB is a rare complication. There were about seventeen cases reported in the world. The location of the tumor in these cases occurs mainly in the gastric antrum, followed by the body, then the pylorus and linitis plastica, and the last was fundus of the stomach. To the best of our knowledge, this is the first case that gastric cancer located in the cardia of stomach after RYGB.

Case Report

A 68-year-old male patient had chronic esophagitis, bile reflux gastritis, and erosive antral gastritis 5 years after RYGB and now developed to aggressive carcinoma in the gastric pouch. In spite of having chemotherapy and traditional Chinese medicine therapy, the patient died of multiple organ failure after 15 months.

Conclusions

This case report highlights the importance to have gastroscopy to observe the proximal small remnant stomach after RYGB in long-term follow-up. Attention must be paid when patients develop symptoms like abdominal pain or excessive weight loss after RYGB. For patients at high risk such as those who have a family history of gastric cancer or presenting abnormal levels of tumor markers should rather undergo Sleeve Gastrectomy plus Jejunojejunal Bypass (SGJB) instead of RYGB.
Literature
1.
go back to reference Raffaelli M, Sessa L, Mingrone G, et al. Assessing the obese diabetic patient for bariatric surgery: which candidate do I choose? Diabetes Metab Syndr Obes. 2015;8:255–62.CrossRefPubMedPubMedCentral Raffaelli M, Sessa L, Mingrone G, et al. Assessing the obese diabetic patient for bariatric surgery: which candidate do I choose? Diabetes Metab Syndr Obes. 2015;8:255–62.CrossRefPubMedPubMedCentral
2.
go back to reference Hopkins JC, Welbourn R. Long-term outcomes of obesity surgery and implications for health system planning. Curr Obes Rep. 2015;4(3):330–6.CrossRefPubMed Hopkins JC, Welbourn R. Long-term outcomes of obesity surgery and implications for health system planning. Curr Obes Rep. 2015;4(3):330–6.CrossRefPubMed
3.
go back to reference Angrisani L, Santonicola A, Iovino P, et al. Bariatric surgery and endoluminal procedures: IFSO worldwide survey 2014. Obes Surg. 2017;27(9):2279–89.CrossRefPubMedPubMedCentral Angrisani L, Santonicola A, Iovino P, et al. Bariatric surgery and endoluminal procedures: IFSO worldwide survey 2014. Obes Surg. 2017;27(9):2279–89.CrossRefPubMedPubMedCentral
4.
go back to reference Lin S, Guan W, Yang N, et al. Short-term outcomes of sleeve gastrectomy plus jejunojejunal bypass: a retrospective comparative study with sleeve Gastrectomy and roux-en-Y gastric bypass in Chinese patients with BMI ≥35 kg/m(2). Obes Surg. 2019;29(4):1352–9.CrossRefPubMed Lin S, Guan W, Yang N, et al. Short-term outcomes of sleeve gastrectomy plus jejunojejunal bypass: a retrospective comparative study with sleeve Gastrectomy and roux-en-Y gastric bypass in Chinese patients with BMI ≥35 kg/m(2). Obes Surg. 2019;29(4):1352–9.CrossRefPubMed
5.
go back to reference Obeid NR, Malick W, Concors SJ, et al. Long-term outcomes after roux-en-Y gastric bypass: 10- to 13-year data. Surg Obes Relat Dis. 2016;12(1):11–20.CrossRefPubMed Obeid NR, Malick W, Concors SJ, et al. Long-term outcomes after roux-en-Y gastric bypass: 10- to 13-year data. Surg Obes Relat Dis. 2016;12(1):11–20.CrossRefPubMed
6.
go back to reference Raijman I, Strother SV, Donegan WL. Gastric cancer after gastric bypass for obesity. Case report J Clin Gastroenterol. 1991;13(2):191–4.CrossRefPubMed Raijman I, Strother SV, Donegan WL. Gastric cancer after gastric bypass for obesity. Case report J Clin Gastroenterol. 1991;13(2):191–4.CrossRefPubMed
7.
go back to reference Harper JL, Beech D, Tichansky DS, et al. Cancer in the bypassed stomach presenting early after gastric bypass. Obes Surg. 2007;17(9):1268–71.CrossRefPubMed Harper JL, Beech D, Tichansky DS, et al. Cancer in the bypassed stomach presenting early after gastric bypass. Obes Surg. 2007;17(9):1268–71.CrossRefPubMed
8.
go back to reference Corsini DA, Simoneti CA, Moreira G, et al. Cancer in the excluded stomach 4 years after gastric bypass. Obes Surg. 2006;16(7):932–4.CrossRefPubMed Corsini DA, Simoneti CA, Moreira G, et al. Cancer in the excluded stomach 4 years after gastric bypass. Obes Surg. 2006;16(7):932–4.CrossRefPubMed
9.
go back to reference Escalona A, Guzman S, Ibanez L, et al. Gastric cancer after roux-en-Y gastric bypass. Obes Surg. 2005;15(3):423–7.CrossRefPubMed Escalona A, Guzman S, Ibanez L, et al. Gastric cancer after roux-en-Y gastric bypass. Obes Surg. 2005;15(3):423–7.CrossRefPubMed
10.
go back to reference Tinoco A, Gottardi LF, Boechat ED. Gastric Cancer in the excluded stomach 10 years after gastric bypass. Case Rep Surg. 2015;2015:468293.PubMedPubMedCentral Tinoco A, Gottardi LF, Boechat ED. Gastric Cancer in the excluded stomach 10 years after gastric bypass. Case Rep Surg. 2015;2015:468293.PubMedPubMedCentral
11.
go back to reference Tornese S, Aiolfi A, Bonitta G, et al. Remnant gastric Cancer after roux-en-Y gastric bypass: narrative review of the literature. Obes Surg. 2019;29(8):2609–13.CrossRefPubMed Tornese S, Aiolfi A, Bonitta G, et al. Remnant gastric Cancer after roux-en-Y gastric bypass: narrative review of the literature. Obes Surg. 2019;29(8):2609–13.CrossRefPubMed
13.
go back to reference Takeno S, Hashimoto T, Maki K, et al. Gastric cancer arising from the remnant stomach after distal gastrectomy: a review. World J Gastroenterol. 2014;20(38):13734–40.CrossRefPubMedPubMedCentral Takeno S, Hashimoto T, Maki K, et al. Gastric cancer arising from the remnant stomach after distal gastrectomy: a review. World J Gastroenterol. 2014;20(38):13734–40.CrossRefPubMedPubMedCentral
14.
15.
go back to reference Orlando G, Pilone V, Vitiello A, et al. Gastric cancer following bariatric surgery: a review. Surg Laparosc Endosc Percutan Tech. 2014;24(5):400–5.CrossRefPubMed Orlando G, Pilone V, Vitiello A, et al. Gastric cancer following bariatric surgery: a review. Surg Laparosc Endosc Percutan Tech. 2014;24(5):400–5.CrossRefPubMed
16.
go back to reference Sundbom M, Hedenstrom H, Gustavsson S. Duodenogastric bile reflux after gastric bypass: a cholescintigraphic study. Dig Dis Sci. 2002;47(8):1891–6.CrossRefPubMed Sundbom M, Hedenstrom H, Gustavsson S. Duodenogastric bile reflux after gastric bypass: a cholescintigraphic study. Dig Dis Sci. 2002;47(8):1891–6.CrossRefPubMed
17.
go back to reference Csendes A, Smok G, Burgos AM, et al. Prospective sequential endoscopic and histologic studies of the gastric pouch in 130 morbidly obese patients submitted to roux-en-Y gastric bypass. Arq Bras Cir Dig. 2012;25(4):245–9.CrossRefPubMed Csendes A, Smok G, Burgos AM, et al. Prospective sequential endoscopic and histologic studies of the gastric pouch in 130 morbidly obese patients submitted to roux-en-Y gastric bypass. Arq Bras Cir Dig. 2012;25(4):245–9.CrossRefPubMed
18.
go back to reference Sinning C, Schaefer N, Standop J, et al. Gastric stump carcinoma - epidemiology and current concepts in pathogenesis and treatment. Eur J Surg Oncol. 2007;33(2):133–9.CrossRefPubMed Sinning C, Schaefer N, Standop J, et al. Gastric stump carcinoma - epidemiology and current concepts in pathogenesis and treatment. Eur J Surg Oncol. 2007;33(2):133–9.CrossRefPubMed
19.
go back to reference Paduraru DN, Nica A, Ion D, et al. Considerations on risk factors correlated to the occurrence of gastric stump cancer. J Med Life. 2016;9(2):130–6.PubMedPubMedCentral Paduraru DN, Nica A, Ion D, et al. Considerations on risk factors correlated to the occurrence of gastric stump cancer. J Med Life. 2016;9(2):130–6.PubMedPubMedCentral
20.
go back to reference Sepulveda M, Alamo M, Preiss Y, et al. Metabolic surgery comparing sleeve gastrectomy with jejunal bypass and roux-en-Y gastric bypass in type 2 diabetic patients after 3 years. Obes Surg. 2018;28(11):3466–73.CrossRefPubMed Sepulveda M, Alamo M, Preiss Y, et al. Metabolic surgery comparing sleeve gastrectomy with jejunal bypass and roux-en-Y gastric bypass in type 2 diabetic patients after 3 years. Obes Surg. 2018;28(11):3466–73.CrossRefPubMed
21.
go back to reference Alamo M, Sepulveda M, Gellona J, et al. Sleeve gastrectomy with jejunal bypass for the treatment of type 2 diabetes mellitus in patients with body mass index <35 kg/m2. A cohort study. Obes Surg. 2012;22(7):1097–103.CrossRefPubMed Alamo M, Sepulveda M, Gellona J, et al. Sleeve gastrectomy with jejunal bypass for the treatment of type 2 diabetes mellitus in patients with body mass index <35 kg/m2. A cohort study. Obes Surg. 2012;22(7):1097–103.CrossRefPubMed
Metadata
Title
Cardia Gastric Cancer in the Gastric Pouch 5 Years after Gastric Bypass: A Case Report
Authors
Wenhui Chen
Guanghui Zhang
Zhiyong Dong
LokWan Liu
Yucheng Wang
Xiaomei Chen
Jinfeng Zhang
Cunchuan Wang
Publication date
01-05-2020
Publisher
Springer US
Published in
Obesity Surgery / Issue 5/2020
Print ISSN: 0960-8923
Electronic ISSN: 1708-0428
DOI
https://doi.org/10.1007/s11695-019-04336-y

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