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Key Symptom 

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  1. Open Access 01-12-2023 | Anxiety | OriginalPaper

    Prevalence and predictors of depressive and anxiety symptoms in a sample of women who use drugs in Tanzania: the key role of drug use stigma

    Poor mental health can adversely affect physical health and quality of life [ 1 , 2 ]. Mental disorders are common among people who use drugs [ 3 – 5 ] and are known barriers to healthcare engagement [ 2 ]. Women who use drugs are particularly …

  2. 01-03-2022 | Dyspnea | OriginalPaper

    Surveillance of COVID-19 using a keyword search for symptoms in reports from emergency medical communication centers in Gironde, France: a 15 year retrospective cross-sectional study

    During periods such as the COVID-19 crisis, there is a need for responsive public health surveillance indicators related to the epidemic. To determine the performance of keyword-search algorithm in call reports to emergency medical communication …

  3. Open Access 26-09-2022 | Care | ReviewPaper

    Is collaborative care a key component for treating pregnant women with psychiatric symptoms (and additional psychosocial problems)? A systematic review

    Mental disorders during pregnancy are common, with long-lasting negative effects on mother and child. Treatment of these women is challenging, because of the high incidence of additional psychosocial problems and barriers on population and …

  4. Open Access 01-06-2022 | Gastric Surgery | OriginalPaper

    Patient perspectives on key symptoms and preferences for follow-up after upper gastro-intestinal cancer surgery

    Upper gastro-intestinal cancer resection (oesophagectomy or gastrectomy) represents a major surgical insult that has a major impact on patients’ quality of life [ 1 ]. Up to 70% of patients experience long-term symptoms after surgery [ 2 , 3 ].

  5. Open Access 01-12-2019 | Bronchial Asthma | OriginalPaper

    Understanding the importance of key risk factors in predicting chronic bronchitic symptoms using a machine learning approach

    Pediatric bronchitic symptoms, especially among children diagnosed with asthma, have been underappreciated and understudied [ 1 – 3 ] and pose a significant clinical and public health burden, with substantial clinical costs, loss of quality of …

  6. 01-06-2019 | Cytokines | ReviewPaper

    Key Role of Inflammation in Myeloproliferative Neoplasms: Instigator of Disease Initiation, Progression. and Symptoms

    Inflammation plays a crucial role in the development and progression of myeloproliferative neoplasms (MPN). Myeloid malignancies are characterized by elevated levels of inflammatory cytokines, which correlate with disease initiation and …

  7. 01-03-2022 | Emergency Medicine

    Correction to: Surveillance of COVID-19 using a keyword search for symptoms in reports from emergency medical communication centers in Gironde, France: a 15 year retrospective cross-sectional study

    In the original publication of the article, the last author given name and family name was swapped. The correct author name is given in this erratum.

  8. Open Access 01-12-2020 | Osteoarthritis of the Hip | OriginalPaper

    Labral calcification plays a key role in hip pain and symptoms in femoroacetabular impingement

    Hip osteoarthritis (HOA) is the most common hip disorder and a major cause of disability in the adult population, with an estimated prevalence of end-stage disease and total hip replacement (THR) [ 1 ]. Thus, the diagnosis, prevention, and …

  9. Pioglitazone Attenuates Lupus Nephritis Symptoms in Mice by Modulating miR-21-5p/TIMP3 Axis: the Key Role of the Activation of Peroxisome Proliferator–Activated Receptor-γ

    Lupus nephritis (LN) is a severe symptom of systemic lupus erythematosus and miR-21-5p is upregulated during LN. In the current study, the effects of pioglitazone (Pg), a peroxisome proliferator–activated receptor-γ (PPARγ) agonist, on LN …

  10. 01-12-2020 | Osteoarthrosis

    Letter to the editor: Labral calcification plays a key role in hip pain and symptoms in femoroacetabular impingement

  11. Response to “Letter to the editor: Labral calcification plays a key role in hip pain and symptoms in femoroacetabular impingement”

  12. 01-08-2018 | OriginalPaper

    CDAKA: A Provably-Secure Heterogeneous Cross-Domain Authenticated Key Agreement Protocol with Symptoms-Matching in TMIS

    Telecare Medical Information System (TMIS) provides the flexible and convenient e-health care. It helps the patients to gain health monitoring information and provides patients to share their experience wirelessly. Traditional authentication and …

  13. Open Access 01-12-2018 | OriginalPaper

    Cohort survey of college students’ eating attitudes: interventions for depressive symptoms and stress coping were key factors for preventing bulimia in a subthreshold group

    Eating disorders are serious illnesses that can be difficult to treat [ 1 ]. Many serious problems are associated with eating disorders [ 2 , 3 ], such as 1) significant mortality rates [ 4 ], 2) suicidal behavior [ 5 , 6 ], 3) high medical costs [ …7

  14. Open Access 01-12-2018 | OriginalPaper

    Patient centred care for the medical treatment of lower urinary tract symptoms in patients with benign prostatic obstruction: a key point to improve patients’ care – a systematic review

    In the last decades Evidence Based Medicine (EBM) has been the cornerstone of the clinical practice [ 1 , 2 ]. Physicians’ personal experience and expertise are often limited by several knowledge biases and gaps, thus EBM intends to ameliorate the …

  15. 01-04-2017 | OriginalPaper

    Key symptoms selection for two major syndromes diagnosis of Chinese medicine in chronic hepatitis B

  16. 01-09-2016 | OriginalPaper

    Psychological factors mediate key symptoms of fibromyalgia through their influence on stress

    The clinical features of fibromyalgia are associated with various psychological factors, including stress. We examined the hypothesis that the path that psychological factors follow in influencing fibromyalgia symptoms is through their direct …

  17. Open Access 01-12-2017 | OriginalPaper

    Risk assessment of manual handling operations at work with the key indicator method (KIM-MHO) — determination of criterion validity regarding the prevalence of musculoskeletal symptoms and clinical conditions within a cross-sectional study

    Symptoms and disorders of the musculoskeletal system (MSDs) are the most common reasons for absence from work in Germany [ 1 ]. 18.9 million days of sick leave were caused by symptoms and disorders of the musculoskeletal system and connective …

  18. Open Access 01-12-2016 | OriginalPaper

    Visceral symptoms as a key diagnostic sign for the early infantile form of Niemann–Pick disease type C in a Russian patient: a case report

    Niemann–Pick disease type C (NP-C) is a rare lysosomal storage disease in which impaired intracellular lipid trafficking leads to excess storage of cholesterol, sphingomyelin, glycosphingolipids, and sphingosine in the brain, liver, spleen, lungs …

  19. 01-01-2015 | EditorialNotes

    Contextual variability of ADHD symptoms: embracement not erasement of a key moderating factor

  20. 01-06-2012 | OriginalPaper

    Urinary urgency: a review of its assessment as the key symptom of the overactive bladder syndrome

    Overactive bladder (OAB) syndrome is a common condition [ 1 – 5 ] that is associated with a significant negative impact on quality of life. The International Continence Society (ICS) defines OAB as urgency, with or without urgency incontinence …

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