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Published in: Journal of General Internal Medicine 11/2019

01-11-2019 | Statins | Capsule Commentary

Capsule Commentary on Marcum et al., Statin Dosing Instructions, Medication Adherence, and Low-Density Lipoprotein Cholesterol: a Cohort Study of Incident Statin Users

Author: Patrick J. O’Connor, MA, MD, MPH

Published in: Journal of General Internal Medicine | Issue 11/2019

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Excerpt

Approximately 1 in 4 US adults are currently prescribed a statin, but many reports estimate that half of patients prescribed statins have suboptimal adherence.1 Complexity of the medication regimen contributes to medication nonadherence, and the majority of patients who take statins are on multiple other medications, often for the control of other cardiometabolic risk factors such as hypertension of type 2 diabetes mellitus.2 Nonadherence to statin therapy has been shown to increase mortality in some studies.3
Literature
1.
go back to reference Grundy SM, Stone NJ, Bailey AL, et al. 2018 AHA/ACC/AACVPR/AAPA/ABC/ACPM/ADA/AGS/APhA/ASPC/NLA/PCNA guideline on the management of blood cholesterol. J Am Coll Cardiol. 2018 November 3 (epub). Grundy SM, Stone NJ, Bailey AL, et al. 2018 AHA/ACC/AACVPR/AAPA/ABC/ACPM/ADA/AGS/APhA/ASPC/NLA/PCNA guideline on the management of blood cholesterol. J Am Coll Cardiol. 2018 November 3 (epub).
2.
go back to reference Kini V, Ho PM. Interventions to improve medication adherence: A review. JAMA 2018;320:2461–2473.CrossRef Kini V, Ho PM. Interventions to improve medication adherence: A review. JAMA 2018;320:2461–2473.CrossRef
3.
go back to reference Ho PM, Magid DJ, Shetterly SM, et al. Medication nonadherence is associated with a broad range of adverse outcomes in patients with coronary artery disease. Am Heart J. 2008;155:772–779.CrossRef Ho PM, Magid DJ, Shetterly SM, et al. Medication nonadherence is associated with a broad range of adverse outcomes in patients with coronary artery disease. Am Heart J. 2008;155:772–779.CrossRef
Metadata
Title
Capsule Commentary on Marcum et al., Statin Dosing Instructions, Medication Adherence, and Low-Density Lipoprotein Cholesterol: a Cohort Study of Incident Statin Users
Author
Patrick J. O’Connor, MA, MD, MPH
Publication date
01-11-2019
Publisher
Springer US
Keyword
Statins
Published in
Journal of General Internal Medicine / Issue 11/2019
Print ISSN: 0884-8734
Electronic ISSN: 1525-1497
DOI
https://doi.org/10.1007/s11606-019-05293-z

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