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Published in: Journal of Neuro-Oncology 3/2014

01-09-2014 | Topic Review

Clinical trials in neurosurgical oncology

Authors: Meghan Murphy, Ian F. Parney

Published in: Journal of Neuro-Oncology | Issue 3/2014

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Abstract

Brain tumors such as diffuse infiltrating gliomas continue to represent a major clinical challenge. Overall survival for patients diagnosed with glioblastoma, the most common primary brain tumor, remains less than 2 years despite intensive multimodal therapy with surgery, radiation, and chemotherapy. However, advances have been made in standard therapies and novel treatments that are showing great potential. These advances reflect careful study performed in the context of clinical trials. Neurosurgeons have played and will continue to play key parts in these studies. In this manuscript, we review clinical trials in neuro-oncology from a neurosurgical point of view and discuss potential roles for neurosurgeons in advancing glioma therapy in the future.
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Metadata
Title
Clinical trials in neurosurgical oncology
Authors
Meghan Murphy
Ian F. Parney
Publication date
01-09-2014
Publisher
Springer US
Published in
Journal of Neuro-Oncology / Issue 3/2014
Print ISSN: 0167-594X
Electronic ISSN: 1573-7373
DOI
https://doi.org/10.1007/s11060-014-1569-0

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