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Published in: Journal of Neuro-Oncology 3/2014

01-09-2014 | Topic Review

Through the patient’s eyes: an emphasis on patient-centered values in operative decision making in the management of malignant glioma

Authors: Adam M. Robin, Steven N. Kalkanis, Jack Rock, Ian Lee, Mark L. Rosenblum

Published in: Journal of Neuro-Oncology | Issue 3/2014

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Abstract

The Joint Section on Tumors of the American Association of Neurological Surgeons and the Congress of Neurological Surgeons is now in its 30th year. In many ways its growth and development has paralleled neurosurgery and medicine as a whole. This is most evident in our endeavor towards more patient-centered care and focus on quantity and quality of life. As the push towards evidence-based care continues, it is important to ensure that individualized care remains a guiding principle. Conscientious surgeons continue to refine techniques and develop technologies that push the boundaries of surgical efficacy while better defining the risks of surgery and the impacts of surgical complications. This article provides a review of the factors involved in minimizing risk and obtaining maximal outcomes for patients through insightful patient selection and evidence-based surgical decision-making. Herein, we present the philosophy and practice of the Hermelin Brain Tumor Center at the Henry Ford Health System as one type of approach to caring for the patient with a malignant glioma.
Literature
1.
go back to reference Knapp PC (1891) The pathology, diagnosis and treatment of intra-cranial growths. Rockwell & Churchill, Boston Knapp PC (1891) The pathology, diagnosis and treatment of intra-cranial growths. Rockwell & Churchill, Boston
2.
go back to reference Knapp PC (1891) A contribution from brain surgery to the study of the localization of the sensory centres in the cerebral cortex. Boston Med Surg J 125:430–433CrossRef Knapp PC (1891) A contribution from brain surgery to the study of the localization of the sensory centres in the cerebral cortex. Boston Med Surg J 125:430–433CrossRef
3.
4.
go back to reference Sanai N, Polley M-Y, McDermott MW, Parsa AT, Berger MS (2011) An extent of resection threshold for newly diagnosed glioblastomas. J Neurosurg 115:3–8PubMedCrossRef Sanai N, Polley M-Y, McDermott MW, Parsa AT, Berger MS (2011) An extent of resection threshold for newly diagnosed glioblastomas. J Neurosurg 115:3–8PubMedCrossRef
5.
go back to reference Lacroix M, Abi-Said D, Fourney DR et al (2001) A multivariate analysis of 416 patients with glioblastoma multiforme: prognosis, extent of resection, and survival. J Neurosurg 95:190–198PubMedCrossRef Lacroix M, Abi-Said D, Fourney DR et al (2001) A multivariate analysis of 416 patients with glioblastoma multiforme: prognosis, extent of resection, and survival. J Neurosurg 95:190–198PubMedCrossRef
6.
go back to reference Stummer W, Pichlmeier U, Meinel T, Wiestler OD, Zanella F, Reulen H-J, ALA-Glioma Study Group (2006) Fluorescence-guided surgery with 5-aminolevulinic acid for resection of malignant glioma: a randomised controlled multicentre phase III trial. Lancet Oncol 7:392–401CrossRef Stummer W, Pichlmeier U, Meinel T, Wiestler OD, Zanella F, Reulen H-J, ALA-Glioma Study Group (2006) Fluorescence-guided surgery with 5-aminolevulinic acid for resection of malignant glioma: a randomised controlled multicentre phase III trial. Lancet Oncol 7:392–401CrossRef
7.
go back to reference Stummer W, van den Bent MJ, Westphal M (2011) Cytoreductive surgery of glioblastoma as the key to successful adjuvant therapies: new arguments in an old discussion. Acta Neurochir (Wien) 153:1211–1218CrossRef Stummer W, van den Bent MJ, Westphal M (2011) Cytoreductive surgery of glioblastoma as the key to successful adjuvant therapies: new arguments in an old discussion. Acta Neurochir (Wien) 153:1211–1218CrossRef
8.
go back to reference McGirt MJ, Mukherjee D, Chaichana KL, Than KD, Weingart JD, Quinones-Hinojosa A (2009) Association of surgically acquired motor and language deficits on overall survival after resection of glioblastoma multiforme. Neurosurgery 65:463–469; discussion 469–470 McGirt MJ, Mukherjee D, Chaichana KL, Than KD, Weingart JD, Quinones-Hinojosa A (2009) Association of surgically acquired motor and language deficits on overall survival after resection of glioblastoma multiforme. Neurosurgery 65:463–469; discussion 469–470
10.
go back to reference Gulati S, Jakola AS, Nerland US, Weber C, Solheim O (2011) The risk of getting worse: surgically acquired deficits, perioperative complications, and functional outcomes after primary resection of glioblastoma. World Neurosurg 76:572–579PubMedCrossRef Gulati S, Jakola AS, Nerland US, Weber C, Solheim O (2011) The risk of getting worse: surgically acquired deficits, perioperative complications, and functional outcomes after primary resection of glioblastoma. World Neurosurg 76:572–579PubMedCrossRef
11.
go back to reference Sawaya R, Hammoud M, Schoppa D, Hess KR, Wu SZ, Shi WM, Wildrick DM (1998) Neurosurgical outcomes in a modern series of 400 craniotomies for treatment of parenchymal tumors. Neurosurgery 42:1044–1055; discussion 1055–1056 Sawaya R, Hammoud M, Schoppa D, Hess KR, Wu SZ, Shi WM, Wildrick DM (1998) Neurosurgical outcomes in a modern series of 400 craniotomies for treatment of parenchymal tumors. Neurosurgery 42:1044–1055; discussion 1055–1056
12.
go back to reference Chang SM, Parney IF, McDermott M et al (2003) Perioperative complications and neurological outcomes of first and second craniotomies among patients enrolled in the Glioma Outcome Project. J Neurosurg 98:1175–1181PubMedCrossRef Chang SM, Parney IF, McDermott M et al (2003) Perioperative complications and neurological outcomes of first and second craniotomies among patients enrolled in the Glioma Outcome Project. J Neurosurg 98:1175–1181PubMedCrossRef
13.
go back to reference Kreth FW, Warnke PC, Scheremet R, Ostertag CB (1993) Surgical resection and radiation therapy versus biopsy and radiation therapy in the treatment of glioblastoma multiforme. J Neurosurg 78:762–766PubMedCrossRef Kreth FW, Warnke PC, Scheremet R, Ostertag CB (1993) Surgical resection and radiation therapy versus biopsy and radiation therapy in the treatment of glioblastoma multiforme. J Neurosurg 78:762–766PubMedCrossRef
14.
go back to reference Mehdorn HM, Schwartz F, Dawirs S, Hedderich J, Dörner L, Nabavi A (2011) High-field iMRI in glioblastoma surgery: improvement of resection radicality and survival for the patient? Acta Neurochir Suppl (Wien) 109:103–106CrossRef Mehdorn HM, Schwartz F, Dawirs S, Hedderich J, Dörner L, Nabavi A (2011) High-field iMRI in glioblastoma surgery: improvement of resection radicality and survival for the patient? Acta Neurochir Suppl (Wien) 109:103–106CrossRef
15.
go back to reference Keles GE, Anderson B, Berger MS (1999) The effect of extent of resection on time to tumor progression and survival in patients with glioblastoma multiforme of the cerebral hemisphere. Surg Neurol 52:371–379PubMedCrossRef Keles GE, Anderson B, Berger MS (1999) The effect of extent of resection on time to tumor progression and survival in patients with glioblastoma multiforme of the cerebral hemisphere. Surg Neurol 52:371–379PubMedCrossRef
16.
go back to reference Barker FG 2nd, Chang SM, Gutin PH, Malec MK, McDermott MW, Prados MD, Wilson CB (1998) Survival and functional status after resection of recurrent glioblastoma multiforme. Neurosurgery 42:709–720; discussion 720–723 Barker FG 2nd, Chang SM, Gutin PH, Malec MK, McDermott MW, Prados MD, Wilson CB (1998) Survival and functional status after resection of recurrent glioblastoma multiforme. Neurosurgery 42:709–720; discussion 720–723
17.
go back to reference Ciric I, Ammirati M, Vick N, Mikhael M (1987) Supratentorial gliomas: surgical considerations and immediate postoperative results. Gross total resection versus partial resection. Neurosurgery 21:21–26PubMedCrossRef Ciric I, Ammirati M, Vick N, Mikhael M (1987) Supratentorial gliomas: surgical considerations and immediate postoperative results. Gross total resection versus partial resection. Neurosurgery 21:21–26PubMedCrossRef
18.
go back to reference Eyüpoglu IY, Buchfelder M, Savaskan NE (2013) Surgical resection of malignant gliomas-role in optimizing patient outcome. Nat Rev Neurol 9:141–151PubMedCrossRef Eyüpoglu IY, Buchfelder M, Savaskan NE (2013) Surgical resection of malignant gliomas-role in optimizing patient outcome. Nat Rev Neurol 9:141–151PubMedCrossRef
19.
go back to reference Pichlmeier U, Bink A, Schackert G, Stummer W, ALA Glioma Study Group (2008) Resection and survival in glioblastoma multiforme: an RTOG recursive partitioning analysis of ALA study patients. Neuro-Oncol 10:1025–1034CrossRef Pichlmeier U, Bink A, Schackert G, Stummer W, ALA Glioma Study Group (2008) Resection and survival in glioblastoma multiforme: an RTOG recursive partitioning analysis of ALA study patients. Neuro-Oncol 10:1025–1034CrossRef
20.
go back to reference Van den Bent MJ, Stupp R, Mason WP, Mirimanoff R, Lacombe D, Gorlia T Impact of extent of resection on overall survival in newly-diagnosed glioblastoma after chemo-irradiation with temozolomide: further analysis of EORTC study 26981 (abstract) Van den Bent MJ, Stupp R, Mason WP, Mirimanoff R, Lacombe D, Gorlia T Impact of extent of resection on overall survival in newly-diagnosed glioblastoma after chemo-irradiation with temozolomide: further analysis of EORTC study 26981 (abstract)
21.
go back to reference Vuorinen V, Hinkka S, Färkkilä M, Jääskeläinen J (2003) Debulking or biopsy of malignant glioma in elderly people—a randomised study. Acta Neurochir (Wien) 145:5–10CrossRef Vuorinen V, Hinkka S, Färkkilä M, Jääskeläinen J (2003) Debulking or biopsy of malignant glioma in elderly people—a randomised study. Acta Neurochir (Wien) 145:5–10CrossRef
22.
go back to reference McGirt MJ, Chaichana KL, Gathinji M et al (2009) Independent association of extent of resection with survival in patients with malignant brain astrocytoma. J Neurosurg 110:156–162PubMedCrossRef McGirt MJ, Chaichana KL, Gathinji M et al (2009) Independent association of extent of resection with survival in patients with malignant brain astrocytoma. J Neurosurg 110:156–162PubMedCrossRef
23.
go back to reference Duffau H, Mandonnet E (2013) The “onco-functional balance” in surgery for diffuse low-grade glioma: integrating the extent of resection with quality of life. Acta Neurochir (Wien) 155:951–957CrossRef Duffau H, Mandonnet E (2013) The “onco-functional balance” in surgery for diffuse low-grade glioma: integrating the extent of resection with quality of life. Acta Neurochir (Wien) 155:951–957CrossRef
24.
go back to reference Díaz JL, Barreto P, Gallego JM, Barbero J, Bayés R, Barcia JA (2009) Proper information during the surgical decision-making process lowers the anxiety of patients with high-grade gliomas. Acta Neurochir (Wien) 151:357–362CrossRef Díaz JL, Barreto P, Gallego JM, Barbero J, Bayés R, Barcia JA (2009) Proper information during the surgical decision-making process lowers the anxiety of patients with high-grade gliomas. Acta Neurochir (Wien) 151:357–362CrossRef
25.
go back to reference Laws ER, Parney IF, Huang W et al (2003) Survival following surgery and prognostic factors for recently diagnosed malignant glioma: data from the Glioma Outcomes Project. J Neurosurg 99:467–473PubMedCrossRef Laws ER, Parney IF, Huang W et al (2003) Survival following surgery and prognostic factors for recently diagnosed malignant glioma: data from the Glioma Outcomes Project. J Neurosurg 99:467–473PubMedCrossRef
26.
go back to reference Glantz MJ, Burger PC, Herndon JE 2nd, Friedman AH, Cairncross JG, Vick NA, Schold SC Jr (1991) Influence of the type of surgery on the histologic diagnosis in patients with anaplastic gliomas. Neurology 41:1741–1744PubMedCrossRef Glantz MJ, Burger PC, Herndon JE 2nd, Friedman AH, Cairncross JG, Vick NA, Schold SC Jr (1991) Influence of the type of surgery on the histologic diagnosis in patients with anaplastic gliomas. Neurology 41:1741–1744PubMedCrossRef
27.
go back to reference Stendel R (2009) Extent of resection and survival in glioblastoma multiforme: identification of and adjustment for bias. Neurosurgery 64:E1206; author reply E1206 Stendel R (2009) Extent of resection and survival in glioblastoma multiforme: identification of and adjustment for bias. Neurosurgery 64:E1206; author reply E1206
28.
go back to reference De Witt Hamer PC, Hendriks EJ, Mandonnet E, Barkhof F, Zwinderman AH, Duffau H (2013) Resection probability maps for quality assessment of glioma surgery without brain location bias. PLoS ONE 8:e73353PubMedCrossRefPubMedCentral De Witt Hamer PC, Hendriks EJ, Mandonnet E, Barkhof F, Zwinderman AH, Duffau H (2013) Resection probability maps for quality assessment of glioma surgery without brain location bias. PLoS ONE 8:e73353PubMedCrossRefPubMedCentral
29.
go back to reference Wilson C (1990) Glioblastoma: the past, the present, and the future. Clinical Neurosurgery. Williams & Wilkins, Los Angeles Wilson C (1990) Glioblastoma: the past, the present, and the future. Clinical Neurosurgery. Williams & Wilkins, Los Angeles
30.
go back to reference Earnest F 4th, Kelly PJ, Scheithauer BW et al (1988) Cerebral astrocytomas: histopathologic correlation of MR and CT contrast enhancement with stereotactic biopsy. Radiology 166:823–827PubMedCrossRef Earnest F 4th, Kelly PJ, Scheithauer BW et al (1988) Cerebral astrocytomas: histopathologic correlation of MR and CT contrast enhancement with stereotactic biopsy. Radiology 166:823–827PubMedCrossRef
31.
go back to reference Kim EY, Yechieli R, Kim JK et al (2014) Patterns of failure after radiosurgery to two different target volumes of enhancing lesions with and without FLAIR abnormalities in recurrent glioblastoma multiforme. J Neurooncol 116:291–297PubMedCrossRef Kim EY, Yechieli R, Kim JK et al (2014) Patterns of failure after radiosurgery to two different target volumes of enhancing lesions with and without FLAIR abnormalities in recurrent glioblastoma multiforme. J Neurooncol 116:291–297PubMedCrossRef
32.
go back to reference Orringer DA, Golby A, Jolesz F (2012) Neuronavigation in the surgical management of brain tumors: current and future trends. Expert Rev Med Devices 9:491–500PubMedCrossRefPubMedCentral Orringer DA, Golby A, Jolesz F (2012) Neuronavigation in the surgical management of brain tumors: current and future trends. Expert Rev Med Devices 9:491–500PubMedCrossRefPubMedCentral
33.
go back to reference Narang J, Jain R, Arbab AS et al (2011) Differentiating treatment-induced necrosis from recurrent/progressive brain tumor using nonmodel-based semiquantitative indices derived from dynamic contrast-enhanced T1-weighted MR perfusion. Neuro-Oncol 13:1037–1046PubMedCrossRefPubMedCentral Narang J, Jain R, Arbab AS et al (2011) Differentiating treatment-induced necrosis from recurrent/progressive brain tumor using nonmodel-based semiquantitative indices derived from dynamic contrast-enhanced T1-weighted MR perfusion. Neuro-Oncol 13:1037–1046PubMedCrossRefPubMedCentral
34.
go back to reference Jolesz FA, Kikinis R, Talos IF (2001) Neuronavigation in interventional MR imaging. Frameless stereotaxy. Neuroimaging Clin N Am 11:685–693, ix Jolesz FA, Kikinis R, Talos IF (2001) Neuronavigation in interventional MR imaging. Frameless stereotaxy. Neuroimaging Clin N Am 11:685–693, ix
35.
go back to reference Hartkens T, Hill DLG, Castellano-Smith AD et al (2003) Measurement and analysis of brain deformation during neurosurgery. IEEE Trans Med Imaging 22:82–92PubMedCrossRef Hartkens T, Hill DLG, Castellano-Smith AD et al (2003) Measurement and analysis of brain deformation during neurosurgery. IEEE Trans Med Imaging 22:82–92PubMedCrossRef
36.
go back to reference Zakhary R, Keles GE, Berger MS (1999) Intraoperative imaging techniques in the treatment of brain tumors. Curr Opin Oncol 11:152–156PubMedCrossRef Zakhary R, Keles GE, Berger MS (1999) Intraoperative imaging techniques in the treatment of brain tumors. Curr Opin Oncol 11:152–156PubMedCrossRef
37.
go back to reference Nimsky C, Ganslandt O, Tomandl B, Buchfelder M, Fahlbusch R (2002) Low-field magnetic resonance imaging for intraoperative use in neurosurgery: a 5-year experience. Eur Radiol 12:2690–2703PubMed Nimsky C, Ganslandt O, Tomandl B, Buchfelder M, Fahlbusch R (2002) Low-field magnetic resonance imaging for intraoperative use in neurosurgery: a 5-year experience. Eur Radiol 12:2690–2703PubMed
38.
go back to reference Schackert G, Steinmetz A, Meier U, Sobottka SB (2001) Surgical management of single and multiple brain metastases: results of a retrospective study. Onkologie 24:246–255PubMedCrossRef Schackert G, Steinmetz A, Meier U, Sobottka SB (2001) Surgical management of single and multiple brain metastases: results of a retrospective study. Onkologie 24:246–255PubMedCrossRef
39.
go back to reference Sanai N, Berger MS (2008) Mapping the horizon: techniques to optimize tumor resection before and during surgery. Clin Neurosurg 55:14–19PubMed Sanai N, Berger MS (2008) Mapping the horizon: techniques to optimize tumor resection before and during surgery. Clin Neurosurg 55:14–19PubMed
40.
go back to reference Sanai N, Mirzadeh Z, Berger MS (2008) Functional outcome after language mapping for glioma resection. N Engl J Med 358:18–27PubMedCrossRef Sanai N, Mirzadeh Z, Berger MS (2008) Functional outcome after language mapping for glioma resection. N Engl J Med 358:18–27PubMedCrossRef
41.
go back to reference Duffau H, Capelle L, Sichez N, Denvil D, Lopes M, Sichez J-P, Bitar A, Fohanno D (2002) Intraoperative mapping of the subcortical language pathways using direct stimulations an anatomo-functional study. Brain 125:199–214PubMedCrossRef Duffau H, Capelle L, Sichez N, Denvil D, Lopes M, Sichez J-P, Bitar A, Fohanno D (2002) Intraoperative mapping of the subcortical language pathways using direct stimulations an anatomo-functional study. Brain 125:199–214PubMedCrossRef
42.
go back to reference Duffau H, Capelle L, Denvil D et al (2003) Usefulness of intraoperative electrical subcortical mapping during surgery for low-grade gliomas located within eloquent brain regions: functional results in a consecutive series of 103 patients. J Neuros 98:764–778CrossRef Duffau H, Capelle L, Denvil D et al (2003) Usefulness of intraoperative electrical subcortical mapping during surgery for low-grade gliomas located within eloquent brain regions: functional results in a consecutive series of 103 patients. J Neuros 98:764–778CrossRef
43.
go back to reference Sanai N, Eschbacher J, Hattendorf G, Coons SW, Preul MC, Smith KA, Nakaji P, Spetzler RF (2011) Intraoperative confocal microscopy for brain tumors: a feasibility analysis in humans. Neurosurgery 68:282–290; discussion 290 Sanai N, Eschbacher J, Hattendorf G, Coons SW, Preul MC, Smith KA, Nakaji P, Spetzler RF (2011) Intraoperative confocal microscopy for brain tumors: a feasibility analysis in humans. Neurosurgery 68:282–290; discussion 290
44.
go back to reference Mohammadi AM, Schroeder JL (2014) Laser interstitial thermal therapy in treatment of brain tumors—the NeuroBlate system. Expert Rev Med Devices 11:109–119PubMedCrossRef Mohammadi AM, Schroeder JL (2014) Laser interstitial thermal therapy in treatment of brain tumors—the NeuroBlate system. Expert Rev Med Devices 11:109–119PubMedCrossRef
45.
go back to reference Stafford RJ, Fuentes D, Elliott AA, Weinberg JS, Ahrar K (2010) Laser-induced thermal therapy for tumor ablation. Crit Rev Biomed Eng 38:79–100PubMedCrossRef Stafford RJ, Fuentes D, Elliott AA, Weinberg JS, Ahrar K (2010) Laser-induced thermal therapy for tumor ablation. Crit Rev Biomed Eng 38:79–100PubMedCrossRef
46.
go back to reference Carpentier A, Chauvet D, Reina V et al (2012) MR-guided laser-induced thermal therapy (LITT) for recurrent glioblastomas. Lasers Surg Med 44:361–368PubMedCrossRef Carpentier A, Chauvet D, Reina V et al (2012) MR-guided laser-induced thermal therapy (LITT) for recurrent glioblastomas. Lasers Surg Med 44:361–368PubMedCrossRef
47.
go back to reference Kalkanis SN, Kast RE, Rosenblum ML et al (2014) Raman spectroscopy to distinguish grey matter, necrosis, and glioblastoma multiforme in frozen tissue sections. J Neurooncol 116:477–485PubMedCrossRef Kalkanis SN, Kast RE, Rosenblum ML et al (2014) Raman spectroscopy to distinguish grey matter, necrosis, and glioblastoma multiforme in frozen tissue sections. J Neurooncol 116:477–485PubMedCrossRef
48.
go back to reference Kircher MF, de la Zerda A, Jokerst JV et al (2012) A brain tumor molecular imaging strategy using a new triple-modality MRI-photoacoustic-Raman nanoparticle. Nat Med 18:829–834PubMedCrossRefPubMedCentral Kircher MF, de la Zerda A, Jokerst JV et al (2012) A brain tumor molecular imaging strategy using a new triple-modality MRI-photoacoustic-Raman nanoparticle. Nat Med 18:829–834PubMedCrossRefPubMedCentral
Metadata
Title
Through the patient’s eyes: an emphasis on patient-centered values in operative decision making in the management of malignant glioma
Authors
Adam M. Robin
Steven N. Kalkanis
Jack Rock
Ian Lee
Mark L. Rosenblum
Publication date
01-09-2014
Publisher
Springer US
Published in
Journal of Neuro-Oncology / Issue 3/2014
Print ISSN: 0167-594X
Electronic ISSN: 1573-7373
DOI
https://doi.org/10.1007/s11060-014-1492-4

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