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01-11-2021 | Immunodeficiency | Letter to Editor

Severe Combined Immunodeficiency (SCID)—the Irish Experience

Authors: Heather Burns, Abigail Collins, Paul Marsden, Terence J. Flood, Mary A. Slatter, Claire Booth, Jinhua Xu-Bayford, Timothy Ronan Leahy

Published in: Journal of Clinical Immunology | Issue 8/2021

Excerpt

Severe combined immunodeficiency (SCID) is an inborn error of immunity characterized by severe T-cell lymphopenia and significant impairment of antigen-specific cellular and humoral immunity. Infants are typically asymptomatic at birth, but present over time with severe and recurrent infections, failure to thrive, and autoimmunity [1]. Universal neonatal screening for SCID has been introduced in many developed countries, leading to earlier diagnosis and better clinical outcomes [2]. …

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Title: Severe Combined Immunodeficiency (SCID)—the Irish Experience
Authors: Heather Burns
Abigail Collins
Paul Marsden
Terence J. Flood
Mary A. Slatter
Claire Booth
Jinhua Xu-Bayford
Timothy Ronan Leahy
Publication date: 01-11-2021
Publisher: Springer US
Keywords: Immunodeficiency
Neonatal Screening
Published in: Journal of Clinical Immunology / Issue 8/2021
Print ISSN: 0271-9142
Electronic ISSN: 1573-2592
DOI: https://doi.org/10.1007/s10875-021-01106-3

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