Skip to main content
Top
Published in: Digestive Diseases and Sciences 5/2022

27-07-2021 | Ulcerative Colitis | Editorial

Does Surveillance Increase Survival? Benefits of Periodic Colonoscopy in Patients with Ulcerative Colitis and Colorectal Cancer

Author: Michael J. Stewart

Published in: Digestive Diseases and Sciences | Issue 5/2022

Login to get access

Excerpt

The development of colorectal cancer (CRC) in patients with inflammatory bowel disease (IBD) has long been recognized as a complication of chronic colitis. Nearly a century ago, Dr. Burrell Crohn described carcinomatous degeneration of the bowel as the terminal stage of ulcerative colitis (UC) [1]. While data from mid-twentieth century suggested markedly high rates of CRC, there has been a steady decline in estimated incidence rates in recent decades, with a 2012 meta-analysis of population-based studies estimating 2.4-fold increased risk compared with the general population [2]. …
Literature
1.
go back to reference Crohn BB, Rosenberg H. The sigmoidoscopic picture of chronic ulcerative colitis (non-specific). Am J Med Sci 1925;170:220–227.CrossRef Crohn BB, Rosenberg H. The sigmoidoscopic picture of chronic ulcerative colitis (non-specific). Am J Med Sci 1925;170:220–227.CrossRef
2.
go back to reference Jess T, Rungoe C, Peyrin-Biroulet L. Risk of colorectal cancer in patients with ulcerative colitis: a meta-analysis of population-based cohort studies. Clin Gastroenterol Hepatol. 2012;10:639–645.CrossRef Jess T, Rungoe C, Peyrin-Biroulet L. Risk of colorectal cancer in patients with ulcerative colitis: a meta-analysis of population-based cohort studies. Clin Gastroenterol Hepatol. 2012;10:639–645.CrossRef
3.
go back to reference Feagins LA, Souza RF, Spechler SJ. Carcinogenesis in IBD: potential targets for the prevention of colorectal cancer. Nat Rev Gastroenterol Hepatol. 2009;6:297–305.CrossRef Feagins LA, Souza RF, Spechler SJ. Carcinogenesis in IBD: potential targets for the prevention of colorectal cancer. Nat Rev Gastroenterol Hepatol. 2009;6:297–305.CrossRef
4.
go back to reference Hu AB, Burke KE, Kochar B, Ananthakrishnan AN. Yield of random biopsies during colonoscopies in inflammatory bowel disease patients undergoing dysplasia surveillance. Inflamm Bowel Dis. 2021;27:779–786.CrossRef Hu AB, Burke KE, Kochar B, Ananthakrishnan AN. Yield of random biopsies during colonoscopies in inflammatory bowel disease patients undergoing dysplasia surveillance. Inflamm Bowel Dis. 2021;27:779–786.CrossRef
5.
go back to reference Fumery M, Dulai PS, Gupta S, Prokop LJ, Ramamoorthy S, Sandborn WJ et al. Incidence, risk factors, and outcomes of colorectal cancer in patients with ulcerative colitis with low-grade dysplasia: a systematic review and meta-analysis. Clin Gastroenterol Hepatol. 2017;15:665-674.e5.CrossRef Fumery M, Dulai PS, Gupta S, Prokop LJ, Ramamoorthy S, Sandborn WJ et al. Incidence, risk factors, and outcomes of colorectal cancer in patients with ulcerative colitis with low-grade dysplasia: a systematic review and meta-analysis. Clin Gastroenterol Hepatol. 2017;15:665-674.e5.CrossRef
6.
go back to reference Karlén P, Kornfeld D, Broström O, Löfberg R, Persson PG, Ekbom A. Is colonoscopic surveillance reducing colorectal cancer mortality in ulcerative colitis? A population based case control study. Gut. 1998;42:711–714.CrossRef Karlén P, Kornfeld D, Broström O, Löfberg R, Persson PG, Ekbom A. Is colonoscopic surveillance reducing colorectal cancer mortality in ulcerative colitis? A population based case control study. Gut. 1998;42:711–714.CrossRef
7.
go back to reference Lashner BA, Kane SV, Hanauer SB. Colon cancer surveillance in chronic ulcerative colitis: historical cohort study. Am J Gastroenterol. 1990;85:1083–1087.PubMed Lashner BA, Kane SV, Hanauer SB. Colon cancer surveillance in chronic ulcerative colitis: historical cohort study. Am J Gastroenterol. 1990;85:1083–1087.PubMed
8.
go back to reference Lutgens M, Oldenburg B, Siersema PD, Van Bodegraven AA, Dijkstra G, Hommes DW et al. Colonoscopic surveillance improves survival after colorectal cancer diagnosis in inflammatory bowel disease. Br J Cancer. 2009;101:1671–1675.CrossRef Lutgens M, Oldenburg B, Siersema PD, Van Bodegraven AA, Dijkstra G, Hommes DW et al. Colonoscopic surveillance improves survival after colorectal cancer diagnosis in inflammatory bowel disease. Br J Cancer. 2009;101:1671–1675.CrossRef
9.
go back to reference Campieri M, Gionchetti P, Belluzzi A, Brignola C, Tampieri M, Iannone P et al. Topical treatment with 5-aminosalicylic in distal ulcerative colitis by using a new suppository preparation A double-blind placebo controlled trial. Int J Color Dis. 1990;5:79–81.CrossRef Campieri M, Gionchetti P, Belluzzi A, Brignola C, Tampieri M, Iannone P et al. Topical treatment with 5-aminosalicylic in distal ulcerative colitis by using a new suppository preparation A double-blind placebo controlled trial. Int J Color Dis. 1990;5:79–81.CrossRef
10.
go back to reference Ananthakrishnan AN, Cagan A, Cai T, Gainer VS, Shaw SY, Churchill S et al. Colonoscopy is associated with a reduced risk for colon cancer and mortality in patients with inflammatory bowel diseases. Clin Gastroenterol Hepatol. 2014;13:322–329.CrossRef Ananthakrishnan AN, Cagan A, Cai T, Gainer VS, Shaw SY, Churchill S et al. Colonoscopy is associated with a reduced risk for colon cancer and mortality in patients with inflammatory bowel diseases. Clin Gastroenterol Hepatol. 2014;13:322–329.CrossRef
12.
go back to reference Choi PM, Nugent FW, Schoetz DJ, Silverman ML, Haggitt RC. Colonoscopic surveillance reduces mortality from colorectal cancer in ulcerative colitis. Gastroenterology. 1993;105:418–424.CrossRef Choi PM, Nugent FW, Schoetz DJ, Silverman ML, Haggitt RC. Colonoscopic surveillance reduces mortality from colorectal cancer in ulcerative colitis. Gastroenterology. 1993;105:418–424.CrossRef
13.
go back to reference Bye WA, Nguyen TM, Parker CE, Jairath V, East JE. Strategies for Detecting Colon Cancer in Patients with Inflammatory Bowel Disease. Vol. 2017, Cochrane Database of Systematic Reviews. 2017. Bye WA, Nguyen TM, Parker CE, Jairath V, East JE. Strategies for Detecting Colon Cancer in Patients with Inflammatory Bowel Disease. Vol. 2017, Cochrane Database of Systematic Reviews. 2017.
Metadata
Title
Does Surveillance Increase Survival? Benefits of Periodic Colonoscopy in Patients with Ulcerative Colitis and Colorectal Cancer
Author
Michael J. Stewart
Publication date
27-07-2021
Publisher
Springer US
Published in
Digestive Diseases and Sciences / Issue 5/2022
Print ISSN: 0163-2116
Electronic ISSN: 1573-2568
DOI
https://doi.org/10.1007/s10620-021-07174-0

Other articles of this Issue 5/2022

Digestive Diseases and Sciences 5/2022 Go to the issue