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Magnetic Resonance Materials in Physics, Biology and Medicine
Published in: Magnetic Resonance Materials in Physics, Biology and Medicine 6/2019

Open Access 01-12-2019 | Review Article

Measurement of T1 and T2 relaxation times of the pancreas at 7 T using a multi-transmit system

Authors: Mariska Damen, Maarten van Leeuwen, Andrew Webb, Dennis Klomp, Catalina Arteaga de Castro

Published in: Magnetic Resonance Materials in Physics, Biology and Medicine | Issue 6/2019

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Abstract

Objective

To determine T1 and T2 relaxation times of healthy pancreas parenchyma at 7 T using a multi-transmit system.

Materials and methods

Twenty-six healthy subjects were scanned with a 7 T MR system using eight parallel transceiver antennas, each with two additional receive loops. A Look-Locker sequence was used to obtain images for T1 determination, while T2 was obtained from spin-echo images and magnetic resonance spectroscopy measurements with different echo times. T1 and T2 times were calculated using a mono-exponential fit of the average magnitude signal from a region of interest in the pancreas and were tested for correlation with age.

Results

The age range of the included subjects was 21–72 years. Average T1 and T2 relaxation times in healthy pancreas were 896 ± 149 ms, and 26.7 ± 5.3 ms, respectively. No correlation with age was found.

Conclusion

T1 and T2 relaxation times of the healthy pancreas were reported for 7 T, which can be used for image acquisition optimization. No significant correlations were found between age and T1 or T2 relaxation times of the pancreas. Considering their low standard deviation and no observable age dependence, these values may be used as a baseline to study potentially pancreatic tissue affected by disease.
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Metadata
Title
Measurement of T1 and T2 relaxation times of the pancreas at 7 T using a multi-transmit system
Authors
Mariska Damen
Maarten van Leeuwen
Andrew Webb
Dennis Klomp
Catalina Arteaga de Castro
Publication date
01-12-2019
Publisher
Springer International Publishing
Published in
Magnetic Resonance Materials in Physics, Biology and Medicine / Issue 6/2019
Print ISSN: 0968-5243
Electronic ISSN: 1352-8661
DOI
https://doi.org/10.1007/s10334-019-00768-w

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