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European Journal of Clinical Microbiology & Infectious Diseases

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01-11-2021 | Cephalosporin Antibiotic | Brief Report

Comparison of stool samples and rectal swabs with and without pre-enrichment for the detection of third-generation cephalosporin-resistant Enterobacterales (3GCREB)

Authors: Tarek Jazmati, Axel Hamprecht, Nathalie Jazmati

Published in: European Journal of Clinical Microbiology & Infectious Diseases | Issue 11/2021

Abstract

To establish the optimal detection of third-generation cephalosporin-resistant Enterobacterales (3GCREB), the performance of four different screening methods has been investigated: stool samples without (A) and with (B) pre-enrichment and rectal swabs without (C) and with (D) pre-enrichment were contrasted. Pre-enrichment approaches (B and D) increased the detection of 3GCREB carriers by 29.4% (20/68 3GCREB carriers only found using pre-enrichment, p < 0.0001) compared to direct plating approaches (A and C). Moreover, the study demonstrates a minor advantage of stool samples in contrast to rectal swabs in both cases (with and without pre-enrichment). Registration number: DRKS00022520, 24 July 2020.

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Title: Comparison of stool samples and rectal swabs with and without pre-enrichment for the detection of third-generation cephalosporin-resistant Enterobacterales (3GCREB)
Authors: Tarek Jazmati
Axel Hamprecht
Nathalie Jazmati
Publication date: 01-11-2021
Publisher: Springer Berlin Heidelberg
Keyword: Cephalosporin Antibiotic
Published in: European Journal of Clinical Microbiology & Infectious Diseases / Issue 11/2021
Print ISSN: 0934-9723
Electronic ISSN: 1435-4373
DOI: https://doi.org/10.1007/s10096-021-04250-1

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Comparison of stool samples and rectal swabs with and without pre-enrichment for the detection of third-generation cephalosporin-resistant Enterobacterales (3GCREB)

Abstract

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