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European Journal of Clinical Microbiology & Infectious Diseases

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01-11-2020 | Escherichia Coli | Brief Report

Evaluation of rapid polymyxin Nordmann Poirel test for detection of polymyxin resistance in clinical isolates of Enterobacteriaceae

Authors: Muhammad Shoaib, Ashfaq Hussain, Luqman Satti, Wajid Hussain, Gohar Zaman, Faisal Hanif

Published in: European Journal of Clinical Microbiology & Infectious Diseases | Issue 11/2020

Abstract

Polymyxins play a significant role against carbapenem-resistant Enterobacteriaceae (CRE). A total of 121 clinical samples yielded growth of CRE that were included in the study. Rapid Polymyxin NP test was performed on all the isolates as described by Nordmann P et al. and results were compared with broth microdilution method. Majority of the isolates were Klebsiella pneumoniae (70.2%) followed by Escherichia coli (17.4%). A total of 71 isolates were found resistant and 50 as susceptible by broth microdilution. Sensitivity and specificity of rapid polymyxin NP test were found to be 97.2% and 100%, respectively. Our study concluded that rapid polymyxin NP test is reliable and can be used as an alternative to broth microdilution in resource limited settings.

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Title: Evaluation of rapid polymyxin Nordmann Poirel test for detection of polymyxin resistance in clinical isolates of Enterobacteriaceae
Authors: Muhammad Shoaib
Ashfaq Hussain
Luqman Satti
Wajid Hussain
Gohar Zaman
Faisal Hanif
Publication date: 01-11-2020
Publisher: Springer Berlin Heidelberg
Keyword: Escherichia Coli
Published in: European Journal of Clinical Microbiology & Infectious Diseases / Issue 11/2020
Print ISSN: 0934-9723
Electronic ISSN: 1435-4373
DOI: https://doi.org/10.1007/s10096-020-03942-4

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