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Neurological Sciences

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01-11-2020 | Magnetic Resonance Imaging | Review Article

Stroke-like migraine attacks after radiation therapy (SMART) syndrome—a case series and review

Authors: Urvish K. Patel, Khush Patel, Preeti Malik, Ahmed Elkady, Nidhi Patel, Abhishek Lunagariya

Published in: Neurological Sciences | Issue 11/2020

Abstract

Introduction

Cranial irradiation is used both prophylactically and for the treatment of brain tumors. There are various complications associated with it. The rare complication of stroke-like migraine attacks after radiation therapy (SMART) syndrome usually occurs several years after radiation therapy but is a reversible phenomenon. It usually presents with headaches, seizures, or other focal neurological deficits concerning stroke or recurrence of the underlying disease.

Objectives

We aim to present two cases of SMART syndrome highlighting the typical presentation, imaging findings, and differential diagnosis. We also conducted the literature review since the early recognition of this rare delayed onset complication is crucial, given its self-limited course and to avoid misinterpretations of the cases.

Conclusion

Our extensive review favors MRI, CT, and prolonged EEG monitoring to rule out other differentials and showed that initiation of corticosteroid therapy and antiepileptic treatment were helpful in the resolution of symptoms and prevent recurrences. Therefore, future studies should be focused on early identification and management guidelines for SMART syndrome.

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Title: Stroke-like migraine attacks after radiation therapy (SMART) syndrome—a case series and review
Authors: Urvish K. Patel
Khush Patel
Preeti Malik
Ahmed Elkady
Nidhi Patel
Abhishek Lunagariya
Publication date: 01-11-2020
Publisher: Springer International Publishing
Keywords: Magnetic Resonance Imaging
Magnetic Resonance Imaging
Migraine
Stroke
Headache
Aphasia
Published in: Neurological Sciences / Issue 11/2020
Print ISSN: 1590-1874
Electronic ISSN: 1590-3478
DOI: https://doi.org/10.1007/s10072-020-04586-0

Keynote webinar | Spotlight on sleep in brain health

Springer Medicine

Stroke-like migraine attacks after radiation therapy (SMART) syndrome—a case series and review

Abstract

Introduction

Objectives

Conclusion

Keynote webinar | Spotlight on sleep in brain health

Springer Medicine

Abstract

Introduction

Objectives

Conclusion

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