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Published in: Neurological Sciences 1/2011

01-02-2011 | Review Article

Parkinson’s disease in China

Authors: You-yong Tian, Cui-ju Tang, Jie Wu, Jun-shan Zhou

Published in: Neurological Sciences | Issue 1/2011

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Abstract

Paralysis agitans was first documented in 1817 by James Parkinson, and therefore the syndrome was named Parkinson’s disease (PD). In fact, as early as more than 2000 years ago, the clinical manifestations of this disease have been described in Chinese medicine classics, such as the “Huangdi Neijing (Yellow Emperor’s Internal Classic)” and “Zhong Zang Jing (Hua’s Zhong Zang Classic).” In recent years, especially in the past 30 years after reform and opening-up, PD has drawn a lot of attention by Chinese scholars. Although great progress in the studies of PD has been made in recent years, the gap between China and western countries still exists. In this review, we concentrate on the main progress made in epidemic characteristics, etiology, diagnosis and management of PD in China.
Literature
1.
go back to reference Zhang ZX, Dong ZH, Román GC (2006) Early descriptions of Parkinson disease in ancient China. Arch Neurol 63:782–784CrossRefPubMed Zhang ZX, Dong ZH, Román GC (2006) Early descriptions of Parkinson disease in ancient China. Arch Neurol 63:782–784CrossRefPubMed
2.
go back to reference Li SC, Schoenberg BS, Wang CC et al (1985) A prevalence survey of Parkinson’s disease and other movement disorders in the People’s Republic of China. Arch Neurol 42:655–657PubMed Li SC, Schoenberg BS, Wang CC et al (1985) A prevalence survey of Parkinson’s disease and other movement disorders in the People’s Republic of China. Arch Neurol 42:655–657PubMed
3.
go back to reference Shi YM, Wang GQ, Xue GB et al (1987) Study on the prevalence of Parkinson disease in Hongkou district, Shanghai. Zhonghua Liu Xing Bing Xue Za Zhi 8:205–207PubMed Shi YM, Wang GQ, Xue GB et al (1987) Study on the prevalence of Parkinson disease in Hongkou district, Shanghai. Zhonghua Liu Xing Bing Xue Za Zhi 8:205–207PubMed
4.
go back to reference Wang YS, Shi YM, Wu ZY et al (1991) Parkinson’s disease in China. Coordinational group of Neuroepidemiology, PLA. Chin Med J 104:960–964PubMed Wang YS, Shi YM, Wu ZY et al (1991) Parkinson’s disease in China. Coordinational group of Neuroepidemiology, PLA. Chin Med J 104:960–964PubMed
5.
go back to reference Ho SC, Woo J, Lee CM (1989) Epidemiologic study of Parkinson’s disease in Hong Kong. Neurology 39:1314–1318PubMed Ho SC, Woo J, Lee CM (1989) Epidemiologic study of Parkinson’s disease in Hong Kong. Neurology 39:1314–1318PubMed
6.
go back to reference Wang SJ, Fuh JL, Teng EL et al (1996) A door-to-door survey of Parkinson’s disease in a Chinese population in Kinmen. Arch Neurol 53:66–71PubMed Wang SJ, Fuh JL, Teng EL et al (1996) A door-to-door survey of Parkinson’s disease in a Chinese population in Kinmen. Arch Neurol 53:66–71PubMed
7.
go back to reference Chen RC, Chang SF, Su CL et al (2001) Prevalence, incidence, and mortality of PD: a door-to-door survey in Ilan county, Taiwan. Neurology 57:1679–1686PubMed Chen RC, Chang SF, Su CL et al (2001) Prevalence, incidence, and mortality of PD: a door-to-door survey in Ilan county, Taiwan. Neurology 57:1679–1686PubMed
8.
go back to reference Tan LC, Venketasubramanian N, Hong CY et al (2004) Prevalence of Parkinson disease in Singapore: Chinese vs. Malays vs. Indians. Neurology 62:1999–2004PubMed Tan LC, Venketasubramanian N, Hong CY et al (2004) Prevalence of Parkinson disease in Singapore: Chinese vs. Malays vs. Indians. Neurology 62:1999–2004PubMed
9.
go back to reference Zhang ZX, Roman GC, Hong Z et al (2005) Parkinson’s disease in China: prevalence in Beijing, Xian, and Shanghai. Lancet 365:595–597PubMed Zhang ZX, Roman GC, Hong Z et al (2005) Parkinson’s disease in China: prevalence in Beijing, Xian, and Shanghai. Lancet 365:595–597PubMed
10.
go back to reference Zhang L, Nie ZY, Liu Y et al (2005) The prevalence of PD in a nutritionally deficient rural population in China. Acta Neurol Scand 112:29–35CrossRefPubMed Zhang L, Nie ZY, Liu Y et al (2005) The prevalence of PD in a nutritionally deficient rural population in China. Acta Neurol Scand 112:29–35CrossRefPubMed
11.
go back to reference Tanner CM, Chen B, Wang W et al (1989) Environmental factors and Parkinson’s disease: a case–control study in China. Neurology 39:660–664PubMed Tanner CM, Chen B, Wang W et al (1989) Environmental factors and Parkinson’s disease: a case–control study in China. Neurology 39:660–664PubMed
12.
go back to reference Tanner CM, Chen B, Wang WZ et al (1987) Environmental factors in the etiology of Parkinson’s disease. Can J Neurol Sci 14(3 Suppl):419–423PubMed Tanner CM, Chen B, Wang WZ et al (1987) Environmental factors in the etiology of Parkinson’s disease. Can J Neurol Sci 14(3 Suppl):419–423PubMed
13.
go back to reference Chan DK, Woo J, Ho SC et al (1998) Genetic and environmental risk factors for Parkinson’s disease in a Chinese population. J Neurol Neurosurg Psychiatry 65:781–784CrossRefPubMed Chan DK, Woo J, Ho SC et al (1998) Genetic and environmental risk factors for Parkinson’s disease in a Chinese population. J Neurol Neurosurg Psychiatry 65:781–784CrossRefPubMed
14.
go back to reference Tan EK, Tan C, Fook-Chong SM et al (2003) Dose-dependent protective effect of coffee, tea, and smoking in Parkinson’s disease: a study in ethnic Chinese. J Neurol Sci 216:163–167CrossRefPubMed Tan EK, Tan C, Fook-Chong SM et al (2003) Dose-dependent protective effect of coffee, tea, and smoking in Parkinson’s disease: a study in ethnic Chinese. J Neurol Sci 216:163–167CrossRefPubMed
15.
go back to reference Tan LC, Koh WP, Yuan JM et al (2008) Differential effects of black versus green tea on risk of Parkinson’s disease in the Singapore Chinese Health Study. Am J Epidemiol 67:553–560 Tan LC, Koh WP, Yuan JM et al (2008) Differential effects of black versus green tea on risk of Parkinson’s disease in the Singapore Chinese Health Study. Am J Epidemiol 67:553–560
16.
go back to reference Ma L, Zhang L, Gao XH et al (2006) Dietary factors and smoking as risk factors for PD in a rural population in China: a nested case–control study. Acta Neurol Scand 113:278–281CrossRefPubMed Ma L, Zhang L, Gao XH et al (2006) Dietary factors and smoking as risk factors for PD in a rural population in China: a nested case–control study. Acta Neurol Scand 113:278–281CrossRefPubMed
17.
go back to reference Wakabayashi K, Takahashi H (2007) Pathology of familial Parkinson’s disease. Brain Nerve 59:851–864PubMed Wakabayashi K, Takahashi H (2007) Pathology of familial Parkinson’s disease. Brain Nerve 59:851–864PubMed
18.
go back to reference Polymeropoulos MH, Higgins JJ, Golbe LI et al (1996) Mapping of a gene for Parkinson’s disease to chromosome 4q21–q23. Science 274:1197–1199CrossRefPubMed Polymeropoulos MH, Higgins JJ, Golbe LI et al (1996) Mapping of a gene for Parkinson’s disease to chromosome 4q21–q23. Science 274:1197–1199CrossRefPubMed
19.
go back to reference Chan DK, Mellick G, Cai H et al (2000) The alpha-synuclein gene and Parkinson disease in a Chinese population. Arch Neurol 57:501–503CrossRefPubMed Chan DK, Mellick G, Cai H et al (2000) The alpha-synuclein gene and Parkinson disease in a Chinese population. Arch Neurol 57:501–503CrossRefPubMed
20.
go back to reference Hu CJ, Sung SM, Liu H et al (1999) No mutation of G209A in the alpha-synuclein gene in sporadic Parkinson’s disease among Taiwan Chinese. Eur Neurol 41:85–87CrossRefPubMed Hu CJ, Sung SM, Liu H et al (1999) No mutation of G209A in the alpha-synuclein gene in sporadic Parkinson’s disease among Taiwan Chinese. Eur Neurol 41:85–87CrossRefPubMed
21.
go back to reference Lin JJ, Yueh KC, Chang DC et al (1999) Absence of G209A and G88C mutations in the alpha-synuclein gene of Parkinson’s disease in a Chinese population. Eur Neurol 42:217–220CrossRefPubMed Lin JJ, Yueh KC, Chang DC et al (1999) Absence of G209A and G88C mutations in the alpha-synuclein gene of Parkinson’s disease in a Chinese population. Eur Neurol 42:217–220CrossRefPubMed
22.
go back to reference Tan EK, Chai A, Teo YY et al (2004) Alpha-synuclein haplotypes implicated in risk of Parkinson’s disease. Neurology 62(1):128–131PubMed Tan EK, Chai A, Teo YY et al (2004) Alpha-synuclein haplotypes implicated in risk of Parkinson’s disease. Neurology 62(1):128–131PubMed
23.
go back to reference Zhao XP, Zheng HM, Xie HJ et al (2004) The alpha-synuclein gene microsatellite polymorphism and lateonset sporadic Parkinson’s disease susceptibility. Zhonghua Yi Xue Yi Chuan Xue Za Zhi 21:339–341PubMed Zhao XP, Zheng HM, Xie HJ et al (2004) The alpha-synuclein gene microsatellite polymorphism and lateonset sporadic Parkinson’s disease susceptibility. Zhonghua Yi Xue Yi Chuan Xue Za Zhi 21:339–341PubMed
24.
go back to reference Fung HC, Chen CM, Hardy J et al (2006) A common genetic factor for Parkinson disease in ethnic Chinese population in Taiwan. BMC Neurol 6:47CrossRefPubMed Fung HC, Chen CM, Hardy J et al (2006) A common genetic factor for Parkinson disease in ethnic Chinese population in Taiwan. BMC Neurol 6:47CrossRefPubMed
25.
go back to reference An XK, Peng R, Li T et al (2008) LRRK2 Gly2385Arg variant is a risk factor of Parkinson’s disease among Han-Chinese from Mainland China. Eur J Neurol 15:301–305CrossRefPubMed An XK, Peng R, Li T et al (2008) LRRK2 Gly2385Arg variant is a risk factor of Parkinson’s disease among Han-Chinese from Mainland China. Eur J Neurol 15:301–305CrossRefPubMed
26.
go back to reference Chan DK, Ng PW, Mok V et al (2008) LRRK2 Gly2385Arg mutation and clinical features in a Chinese population with early-onset Parkinson’s disease compared to late-onset patients. J Neural Transm 115:1275–1277CrossRefPubMed Chan DK, Ng PW, Mok V et al (2008) LRRK2 Gly2385Arg mutation and clinical features in a Chinese population with early-onset Parkinson’s disease compared to late-onset patients. J Neural Transm 115:1275–1277CrossRefPubMed
27.
go back to reference Li C, Ting Z, Qin X et al (2007) The prevalence of LRRK2 Gly2835Arg variant in Han Chinese population with Parkinson’s disease. Mov Disord 22:2439–2443CrossRefPubMed Li C, Ting Z, Qin X et al (2007) The prevalence of LRRK2 Gly2835Arg variant in Han Chinese population with Parkinson’s disease. Mov Disord 22:2439–2443CrossRefPubMed
28.
go back to reference Ross OA, Wu YR, Lee MC et al (2008) Analysis of LRRK2 R1628P as a risk factor for Parkinson’s disease. Ann Neurol 64:88–92CrossRefPubMed Ross OA, Wu YR, Lee MC et al (2008) Analysis of LRRK2 R1628P as a risk factor for Parkinson’s disease. Ann Neurol 64:88–92CrossRefPubMed
29.
go back to reference Lu CS, Wu-Chan YH, Van Doeselaar M et al (2008) The LRRK2 Arg1628Pro variant is a risk factor for Parkinson’s disease in the Chinese population. Neurogenetics 9:271–276CrossRefPubMed Lu CS, Wu-Chan YH, Van Doeselaar M et al (2008) The LRRK2 Arg1628Pro variant is a risk factor for Parkinson’s disease in the Chinese population. Neurogenetics 9:271–276CrossRefPubMed
30.
go back to reference Wu T, Zeng Y, Ding X et al (2006) A novel P755L mutation in LRRK2 gene associated with Parkinson’s disease. Neuroreport 17:1859–1862CrossRefPubMed Wu T, Zeng Y, Ding X et al (2006) A novel P755L mutation in LRRK2 gene associated with Parkinson’s disease. Neuroreport 17:1859–1862CrossRefPubMed
31.
go back to reference Hao YX, Zhang J, Fang CP et al (2008) Association of two polymorphisms in ubiquitin carboxy-terminal hydrolase-L1 gene with Parkinson’s disease in Shanghai. Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 25:272–275PubMed Hao YX, Zhang J, Fang CP et al (2008) Association of two polymorphisms in ubiquitin carboxy-terminal hydrolase-L1 gene with Parkinson’s disease in Shanghai. Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 25:272–275PubMed
32.
go back to reference Wang J, Zhao CY, Si YM et al (2002) ACT and UCH-L1 polymorphisms in Parkinson’s disease and age of onset. Mov Disord 17:767–771CrossRefPubMed Wang J, Zhao CY, Si YM et al (2002) ACT and UCH-L1 polymorphisms in Parkinson’s disease and age of onset. Mov Disord 17:767–771CrossRefPubMed
33.
go back to reference Xiao Y, Zhang B (2008) Association of the ubiquitin carboxy-terminal hydrolase-L1 genetic polymorphism with the susceptibility of Parkinson’s disease. Zhonghua Yi Xue Yi Chuan Xue Za Zhi 25:586–587PubMed Xiao Y, Zhang B (2008) Association of the ubiquitin carboxy-terminal hydrolase-L1 genetic polymorphism with the susceptibility of Parkinson’s disease. Zhonghua Yi Xue Yi Chuan Xue Za Zhi 25:586–587PubMed
34.
go back to reference Zhang ZJ, Burgunder JM, An XK et al (2008) Lack of evidence for association of a UCH-L1 S18Y polymorphism with Parkinson’s disease in a Han-Chinese population. Neurosci Lett 442:200–202CrossRefPubMed Zhang ZJ, Burgunder JM, An XK et al (2008) Lack of evidence for association of a UCH-L1 S18Y polymorphism with Parkinson’s disease in a Han-Chinese population. Neurosci Lett 442:200–202CrossRefPubMed
35.
go back to reference Chan DK, Mok V, Ng PW et al (2008) PARK2 mutations and clinical features in a Chinese population with early-onset Parkinson’s disease. J Neural Transm 115:715–719CrossRefPubMed Chan DK, Mok V, Ng PW et al (2008) PARK2 mutations and clinical features in a Chinese population with early-onset Parkinson’s disease. J Neural Transm 115:715–719CrossRefPubMed
36.
go back to reference Shyu WC, Lin SZ, Chiang MF et al (2005) Early-onset Parkinson’s disease in a Chinese population: 99mTc-TRODAT-1 SPECT, Parkin gene analysis and clinical study. Parkinsonism Relat Disord 11(3):173–180CrossRefPubMed Shyu WC, Lin SZ, Chiang MF et al (2005) Early-onset Parkinson’s disease in a Chinese population: 99mTc-TRODAT-1 SPECT, Parkin gene analysis and clinical study. Parkinsonism Relat Disord 11(3):173–180CrossRefPubMed
37.
go back to reference Wu RM, Bounds R, Lincoln S et al (2005) Parkin mutations and early-onset parkinsonism in a Taiwanese cohort. Arch Neurol 62:82–87CrossRefPubMed Wu RM, Bounds R, Lincoln S et al (2005) Parkin mutations and early-onset parkinsonism in a Taiwanese cohort. Arch Neurol 62:82–87CrossRefPubMed
38.
go back to reference Wu RM, Shan DE, Sun CM et al (2002) Clinical, 18F-dopa PET, and genetic analysis of an ethnic Chinese kindred with early-onset parkinsonism and parkin gene mutations. Mov Disord 17:670–675CrossRefPubMed Wu RM, Shan DE, Sun CM et al (2002) Clinical, 18F-dopa PET, and genetic analysis of an ethnic Chinese kindred with early-onset parkinsonism and parkin gene mutations. Mov Disord 17:670–675CrossRefPubMed
39.
go back to reference Tan EK, Puong KY, Chan DK et al (2005) Impaired transcriptional upregulation of Parkin promoter variant under oxidative stress and proteasomal inhibition: clinical association. Hum Genet 118:484–488CrossRefPubMed Tan EK, Puong KY, Chan DK et al (2005) Impaired transcriptional upregulation of Parkin promoter variant under oxidative stress and proteasomal inhibition: clinical association. Hum Genet 118:484–488CrossRefPubMed
40.
go back to reference Taylor JM, Wu RM, Lin CH et al (2009) Lack of evidence for association of a parkin promoter polymorphism with early-onset Parkinson’s disease in a Chinese population. Parkinsonism Relat Disord 15:149–152CrossRefPubMed Taylor JM, Wu RM, Lin CH et al (2009) Lack of evidence for association of a parkin promoter polymorphism with early-onset Parkinson’s disease in a Chinese population. Parkinsonism Relat Disord 15:149–152CrossRefPubMed
41.
go back to reference Peng R, Gou Y, Yuan Q et al (2003) Mutation screening and association analysis of the parkin gene in Parkinson’s disease patients from South-West China. Eur Neurol 49:85–89CrossRefPubMed Peng R, Gou Y, Yuan Q et al (2003) Mutation screening and association analysis of the parkin gene in Parkinson’s disease patients from South-West China. Eur Neurol 49:85–89CrossRefPubMed
42.
go back to reference Wang F, Chen B, Feng XL et al (2007) PINK1 IVS5–5 G>A polymorphism may contribute to the risk of late onset Parkinson disease in Chinese. Zhonghua Yi Xue Yi Chuan Xue Za Zhi 24:305–309PubMed Wang F, Chen B, Feng XL et al (2007) PINK1 IVS5–5 G>A polymorphism may contribute to the risk of late onset Parkinson disease in Chinese. Zhonghua Yi Xue Yi Chuan Xue Za Zhi 24:305–309PubMed
43.
go back to reference Wang F, Feng X, Ma J et al (2006) A common A340T variant in PINK1 gene associated with late-onset Parkinson’s disease in Chinese. Neurosci Lett 410:121–125CrossRefPubMed Wang F, Feng X, Ma J et al (2006) A common A340T variant in PINK1 gene associated with late-onset Parkinson’s disease in Chinese. Neurosci Lett 410:121–125CrossRefPubMed
44.
go back to reference Chan DK, Mellick GD, Buchanan DD et al (2002) Lack of association between CYP1A1 polymorphism and Parkinson’s disease in a Chinese population. J Neural Transm 109:35–39CrossRefPubMed Chan DK, Mellick GD, Buchanan DD et al (2002) Lack of association between CYP1A1 polymorphism and Parkinson’s disease in a Chinese population. J Neural Transm 109:35–39CrossRefPubMed
45.
go back to reference Wang J, Liu Z, Chan P (2000) Lack of association between cytochrome P450 2E1 gene polymorphisms and Parkinson’s disease in a Chinese population. Mov Disord 15:1267–1269CrossRefPubMed Wang J, Liu Z, Chan P (2000) Lack of association between cytochrome P450 2E1 gene polymorphisms and Parkinson’s disease in a Chinese population. Mov Disord 15:1267–1269CrossRefPubMed
46.
go back to reference Chan DK, Lam MK, Wong R et al (2003) Strong association between N-acetyltransferase 2 genotype and PD in Hong Kong Chinese. Neurology 60:1002–1005PubMed Chan DK, Lam MK, Wong R et al (2003) Strong association between N-acetyltransferase 2 genotype and PD in Hong Kong Chinese. Neurology 60:1002–1005PubMed
47.
go back to reference Lee CG, Tang K, Cheung YB et al (2004) MDR1, the blood-brain barrier transporter, is associated with Parkinson’s disease in ethnic Chinese. J Med Genet 41:e60CrossRefPubMed Lee CG, Tang K, Cheung YB et al (2004) MDR1, the blood-brain barrier transporter, is associated with Parkinson’s disease in ethnic Chinese. J Med Genet 41:e60CrossRefPubMed
48.
go back to reference Tang G, Zhang M, Xie H et al (2002) Alpha-2 macroglobulin I1000 V polymorphism in Chinese sporadic Alzheimer’s disease and Parkinson’s disease. Neurosci Lett 328:195–197CrossRefPubMed Tang G, Zhang M, Xie H et al (2002) Alpha-2 macroglobulin I1000 V polymorphism in Chinese sporadic Alzheimer’s disease and Parkinson’s disease. Neurosci Lett 328:195–197CrossRefPubMed
49.
go back to reference Tang G, Xie H, Xu L et al (2002) Genetic study of apolipoprotein E gene, alpha-1 antichymotrypsin gene in sporadic Parkinson disease. Am J Med Genet 114:446–449CrossRefPubMed Tang G, Xie H, Xu L et al (2002) Genetic study of apolipoprotein E gene, alpha-1 antichymotrypsin gene in sporadic Parkinson disease. Am J Med Genet 114:446–449CrossRefPubMed
50.
go back to reference Jiang G, Xu L, Wang L et al (2008) Association study of human MTH1 Ile45Thr polymorphism with sporadic Parkinson’s disease. Eur Neurol 59:15–17CrossRefPubMed Jiang G, Xu L, Wang L et al (2008) Association study of human MTH1 Ile45Thr polymorphism with sporadic Parkinson’s disease. Eur Neurol 59:15–17CrossRefPubMed
51.
go back to reference Han Y, Zhang XH, Chen T et al (2008) The survey for the diagnosis and treatment of Parkinson’s disease. Zhonghua Bao Jian Yi Xue Za Zhi 10:18–20 Han Y, Zhang XH, Chen T et al (2008) The survey for the diagnosis and treatment of Parkinson’s disease. Zhonghua Bao Jian Yi Xue Za Zhi 10:18–20
52.
go back to reference Zhang ZX (The Group of Movement disorders and Parkinson’s disease, Neurologic Branch of Chinese Medical Association) (2006) The diagnosis of Parkinson’s disease. Zhonghua Shen Jing Ke Za Zhi 39: 408–409 Zhang ZX (The Group of Movement disorders and Parkinson’s disease, Neurologic Branch of Chinese Medical Association) (2006) The diagnosis of Parkinson’s disease. Zhonghua Shen Jing Ke Za Zhi 39: 408–409
53.
go back to reference Feng F, You H, Wang H et al (2009) Phase-weighted imaging in differentiating multiple system atrophy from idiopathic Parkinson disease. Zhongguo Yi Xue Ke Xue Yuan Xue Bao 31:129–133PubMed Feng F, You H, Wang H et al (2009) Phase-weighted imaging in differentiating multiple system atrophy from idiopathic Parkinson disease. Zhongguo Yi Xue Ke Xue Yuan Xue Bao 31:129–133PubMed
54.
go back to reference Chen SD (The Group of Movement Disorders and Parkinson’s Disease, Neurologic Branch of Chinese Medical Association) (2006) The guideline for management of Parkinson’s disease. Zhonghua Shen Jing Ke Za Zhi 39:409–412 Chen SD (The Group of Movement Disorders and Parkinson’s Disease, Neurologic Branch of Chinese Medical Association) (2006) The guideline for management of Parkinson’s disease. Zhonghua Shen Jing Ke Za Zhi 39:409–412
55.
go back to reference Wang X, Liang XB, Li FQ et al (2008) Therapeutic strategies for Parkinson’s disease: the ancient meets the future—traditional Chinese herbal medicine, electroacupuncture, gene therapy and stem cells. Neurochem Res 33:1956–1963CrossRefPubMed Wang X, Liang XB, Li FQ et al (2008) Therapeutic strategies for Parkinson’s disease: the ancient meets the future—traditional Chinese herbal medicine, electroacupuncture, gene therapy and stem cells. Neurochem Res 33:1956–1963CrossRefPubMed
56.
go back to reference Li JY, Yang MH, Dou YQ et al (2008) TCM therapy for Parkinson’s disease. Beijing Zhong Yi Xue Za Zhi 27:300–302 Li JY, Yang MH, Dou YQ et al (2008) TCM therapy for Parkinson’s disease. Beijing Zhong Yi Xue Za Zhi 27:300–302
57.
go back to reference Ren XM (2008) Fifty cases of Parkinson’s disease treated by acupuncture combined with madopar. J Tradit Chin Med 28:255–257CrossRefPubMed Ren XM (2008) Fifty cases of Parkinson’s disease treated by acupuncture combined with madopar. J Tradit Chin Med 28:255–257CrossRefPubMed
58.
go back to reference Liang XB, Liu XY, Li FQ et al (2002) Long-term high-frequency electro-acupuncture stimulation prevents neuronal degeneration and up-regulates BDNF mRNA in the substantia nigra and ventral tegmental area following medial forebrain bundle axotomy. Brain Res Mol Brain Res 108:51–59CrossRefPubMed Liang XB, Liu XY, Li FQ et al (2002) Long-term high-frequency electro-acupuncture stimulation prevents neuronal degeneration and up-regulates BDNF mRNA in the substantia nigra and ventral tegmental area following medial forebrain bundle axotomy. Brain Res Mol Brain Res 108:51–59CrossRefPubMed
59.
go back to reference Lam YC, Kum WF, Durairajan SS et al (2008) Efficacy and safety of acupuncture for idiopathic Parkinson’s disease: a systematic review. J Altern Complement Med 14:663–671CrossRefPubMed Lam YC, Kum WF, Durairajan SS et al (2008) Efficacy and safety of acupuncture for idiopathic Parkinson’s disease: a systematic review. J Altern Complement Med 14:663–671CrossRefPubMed
60.
go back to reference Sun B, Lang LQ, Cong PY et al (2001) History of Chinese stereotactic and functional neurosurgery. Stereotact Funct Neurosurg 717:17–19CrossRef Sun B, Lang LQ, Cong PY et al (2001) History of Chinese stereotactic and functional neurosurgery. Stereotact Funct Neurosurg 717:17–19CrossRef
61.
go back to reference Iacono RP, Tang ZS, Mazziotta JC et al (1992) Bilateral fetal grafts for Parkinson’s disease: 22 months’ results. Stereotact Funct Neurosurg 58:84–87CrossRefPubMed Iacono RP, Tang ZS, Mazziotta JC et al (1992) Bilateral fetal grafts for Parkinson’s disease: 22 months’ results. Stereotact Funct Neurosurg 58:84–87CrossRefPubMed
62.
go back to reference Liu J, Huang HY (2007) How to improve the survival of the fetal ventral mesencephalic cell transplanted in Parkinson’s disease? Neurosci Bull 23:377–382CrossRefPubMed Liu J, Huang HY (2007) How to improve the survival of the fetal ventral mesencephalic cell transplanted in Parkinson’s disease? Neurosci Bull 23:377–382CrossRefPubMed
63.
go back to reference Zhang ZX, Anderson DW, Huang JB et al (2003) Prevalence of Parkinson’s disease and related disorders in the elderly population of greater Beijing, China. Mov Disord 18:764–772CrossRefPubMed Zhang ZX, Anderson DW, Huang JB et al (2003) Prevalence of Parkinson’s disease and related disorders in the elderly population of greater Beijing, China. Mov Disord 18:764–772CrossRefPubMed
64.
go back to reference Woo J, Lau E, Ziea E et al (2004) Prevalence of Parkinson’s disease in a Chinese population. Acta Neurol Scand 109:228–231CrossRefPubMed Woo J, Lau E, Ziea E et al (2004) Prevalence of Parkinson’s disease in a Chinese population. Acta Neurol Scand 109:228–231CrossRefPubMed
Metadata
Title
Parkinson’s disease in China
Authors
You-yong Tian
Cui-ju Tang
Jie Wu
Jun-shan Zhou
Publication date
01-02-2011
Publisher
Springer Milan
Published in
Neurological Sciences / Issue 1/2011
Print ISSN: 1590-1874
Electronic ISSN: 1590-3478
DOI
https://doi.org/10.1007/s10072-010-0461-8

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