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Published in: Archives of Virology 6/2016

01-06-2016 | Annotated Sequence Record

Complete genome analysis of coxsackievirus A24 isolated in Yunnan, China, in 2013

Authors: Yilin Zhao, Jiansheng Liu, Haihao Zhang, Chen Guo, Longhui Xia, Fang Yang, Huai Yang, Qinxing Yang, Zhaoqing Yang, Shaohui Ma

Published in: Archives of Virology | Issue 6/2016

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Abstract

Human coxsackievirus A24 (CVA24) belongs to the species Enterovirus C, and variants of this virus frequently cause acute hemorrhagic conjunctivitis (AHC). The complete genome of the K282/YN/CHN/2013 strain, isolated from a healthy child in Yunnan, China, in 2013, is reported here for the first time. The strain showed 80.0 % and 79.9 % nucleotide sequence identity to CVA24 prototype strain Joseph and CVA24 variant prototype EH24, respectively. The K282/YN/CHN/2013 strain belongs to the CVA24 serotype. Twelve amino acid differences, most of which are in structural regions, were found between the CVA24 and CVA24v strains. In the whole-length genome sequence, only the structural region of K282/YN/CHN/2013 was similar to that of the CVA24 strains; the other genome regions were more similar to those of other members of the species Enterovirus C. Recombination analysis showed evidence of recombination with other viruses of the same species.
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Metadata
Title
Complete genome analysis of coxsackievirus A24 isolated in Yunnan, China, in 2013
Authors
Yilin Zhao
Jiansheng Liu
Haihao Zhang
Chen Guo
Longhui Xia
Fang Yang
Huai Yang
Qinxing Yang
Zhaoqing Yang
Shaohui Ma
Publication date
01-06-2016
Publisher
Springer Vienna
Published in
Archives of Virology / Issue 6/2016
Print ISSN: 0304-8608
Electronic ISSN: 1432-8798
DOI
https://doi.org/10.1007/s00705-016-2792-0

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