Skip to main content
Top
Published in: European Spine Journal 3/2018

01-07-2018 | Case Report

Corrosion of Harrington rod in idiopathic scoliosis: long-term effects

Authors: Beth Sherman, Tanya Crowell

Published in: European Spine Journal | Special Issue 3/2018

Login to get access

Abstract

Purpose

Metal implants have been used to treat adolescent idiopathic scoliosis since the 1960s. Only recently, however, it has the issue of metal-bone breakdown secondary to metal corrosion in situ come to light, raising concerns of possible long-term complications from the resulting metallosis and inflammation of spinal tissues. We present a case of a patient with neurological deficit, pain, and disability with Harrington rod in place for over 30 years, to bring attention to the issue of bio-corrosion of metal implants and its effect on human tissue. We call attention to the need for protocols to better diagnose and treat these patients.

Methods

We provide a complete review of the history and clinical manifestations as well as serum metal, X-ray, and CT/myelogram test results.

Results

A 52-year-old female with spinal fusion and Harrington rod presents with pain, lymphedema, disability, and neurological deficits including thoracic outlet syndrome, hyperreflexia, peripheral muscle weakness and atrophy, hypertonicity, Raynaud’s phenomenon, and balance and gait abnormalities. Serum chromium levels were elevated (26.73 nmol). X-rays showed no evidence of rod breakdown. Serial X-rays can demonstrate subtle corrosive changes but were not available. Adhesive arachnoiditis was diagnosed via CT/myelogram.

Conclusion

We hypothesize that bio-corrosion is present in this case and that it is associated with intraspinal metallosis. Trauma secondary to a motor vehicle accident, as well as arachnoiditis, and their possible effects on this case are outlined. Challenges in proper diagnosis and management are discussed.
Literature
1.
go back to reference Akazawa T, Minami S, Takahashi K, Kotani T, Hanawa T, Moriya H (2005) Corrosion of spinal implants retrieved from patients with scoliosis. J Orthop Sci 10:200–205CrossRefPubMed Akazawa T, Minami S, Takahashi K, Kotani T, Hanawa T, Moriya H (2005) Corrosion of spinal implants retrieved from patients with scoliosis. J Orthop Sci 10:200–205CrossRefPubMed
2.
go back to reference Aulisa L, di Benedetto A, Vinciguerra A, Lorini G, Tranquilli-Leali P (1982) Corrosion of the Harrington’s instrumentation and biological behaviour of the rod-human spine system. Biomaterials 3:246–248CrossRefPubMed Aulisa L, di Benedetto A, Vinciguerra A, Lorini G, Tranquilli-Leali P (1982) Corrosion of the Harrington’s instrumentation and biological behaviour of the rod-human spine system. Biomaterials 3:246–248CrossRefPubMed
3.
4.
go back to reference Cundy WJ, Mascarenhas AR, Antoniou G, Freeman BJC, Cundy PJ (2015) Local and systemic metal ion release occurs intraoperatively during correction and instrumented spinal fusion for scoliosis. J Child Orthop 9:39–43CrossRefPubMedPubMedCentral Cundy WJ, Mascarenhas AR, Antoniou G, Freeman BJC, Cundy PJ (2015) Local and systemic metal ion release occurs intraoperatively during correction and instrumented spinal fusion for scoliosis. J Child Orthop 9:39–43CrossRefPubMedPubMedCentral
5.
go back to reference Cundy TP, Delaney CL, Rackham MD et al (2010) Chromium ion release from stainless steel pediatric scoliosis instrumentation. Spine 35:967–974CrossRefPubMed Cundy TP, Delaney CL, Rackham MD et al (2010) Chromium ion release from stainless steel pediatric scoliosis instrumentation. Spine 35:967–974CrossRefPubMed
8.
go back to reference Kirkpatrick JS, Venugopalan R, Beck P, Lemons J (2005) Corrosion on spinal implants. J Spinal Disord Tech 18:247–251PubMed Kirkpatrick JS, Venugopalan R, Beck P, Lemons J (2005) Corrosion on spinal implants. J Spinal Disord Tech 18:247–251PubMed
9.
go back to reference McPhee IB, Swanson CE (2007) Metal ion levels in patients with stainless steel spinal instrumentation. Spine 18:1963–1968CrossRef McPhee IB, Swanson CE (2007) Metal ion levels in patients with stainless steel spinal instrumentation. Spine 18:1963–1968CrossRef
10.
go back to reference Prikryl M, Srivastava SC, Viviani GR, Ives MB, Purdy GR (1989) Role of corrosion in Harrington and Luque rods failure. Biomaterials 10:109–117CrossRefPubMed Prikryl M, Srivastava SC, Viviani GR, Ives MB, Purdy GR (1989) Role of corrosion in Harrington and Luque rods failure. Biomaterials 10:109–117CrossRefPubMed
12.
go back to reference Caicedo MS, Desai R, McAllister K, Reddy A, Jacobs JJ, Hallab NJ (2009) Soluble and particulate Co–Cr–Mo alloy implant metals activate the inflammasome danger signaling pathway in human macrophages: a novel mechanism for implant debris reactivity. J Orthop Res 27:847–854. doi:10.1002/jor.20826 CrossRefPubMed Caicedo MS, Desai R, McAllister K, Reddy A, Jacobs JJ, Hallab NJ (2009) Soluble and particulate Co–Cr–Mo alloy implant metals activate the inflammasome danger signaling pathway in human macrophages: a novel mechanism for implant debris reactivity. J Orthop Res 27:847–854. doi:10.​1002/​jor.​20826 CrossRefPubMed
13.
go back to reference Gristina AG (1994) Implant failure and the immune-incompetent fibro-inflammatory zone. Clin Orthop Relat Res 298:106–118 Gristina AG (1994) Implant failure and the immune-incompetent fibro-inflammatory zone. Clin Orthop Relat Res 298:106–118
15.
go back to reference Torgerson S, Moe G, Jonsson R (1995) Immunocompetent cells adjacent to stainless steel and titanium miniplates and screws. Eur J Oral Sci 103:46–54CrossRef Torgerson S, Moe G, Jonsson R (1995) Immunocompetent cells adjacent to stainless steel and titanium miniplates and screws. Eur J Oral Sci 103:46–54CrossRef
16.
go back to reference Takahashi S, Delecrin J, Passuti N (2001) Intraspinal metallosis causing delayed neurologic symptoms after spinal instrumentation surgery. Spine 26:1495–1499CrossRefPubMed Takahashi S, Delecrin J, Passuti N (2001) Intraspinal metallosis causing delayed neurologic symptoms after spinal instrumentation surgery. Spine 26:1495–1499CrossRefPubMed
17.
go back to reference Beguiristain J, del Rio J, Duart J, Barroso J, Silva A, Villas C (2006) Corrosion and late infection causing delayed paraparesis after spinal instrumentation. J Pediatr Orthop B 15:321–323CrossRef Beguiristain J, del Rio J, Duart J, Barroso J, Silva A, Villas C (2006) Corrosion and late infection causing delayed paraparesis after spinal instrumentation. J Pediatr Orthop B 15:321–323CrossRef
19.
go back to reference Villarraga M, Cripton P, Teti S et al (2006) Wear and corrosion in retrieved thoracolumbar posterior internal fixation. Spine 31:2454–2462CrossRefPubMed Villarraga M, Cripton P, Teti S et al (2006) Wear and corrosion in retrieved thoracolumbar posterior internal fixation. Spine 31:2454–2462CrossRefPubMed
20.
go back to reference Yanese M, Sakou T, Taketomi E, Yone K (1995) Transpedicular fixation of the lumbar and lumbosacral spine with screws. Application of the Diapason system. Paraplegia 33:216–218 Yanese M, Sakou T, Taketomi E, Yone K (1995) Transpedicular fixation of the lumbar and lumbosacral spine with screws. Application of the Diapason system. Paraplegia 33:216–218
21.
go back to reference Francois J, Coessens R, Lauweryns P (2007) Early removal of a Maverick disc prosthesis: surgical findings and morphological changes. Acta Orthop Belg 73:122–127PubMed Francois J, Coessens R, Lauweryns P (2007) Early removal of a Maverick disc prosthesis: surgical findings and morphological changes. Acta Orthop Belg 73:122–127PubMed
22.
go back to reference Peterson HA (2005) Metallic implant removal in children. J Pediatr Orthop 25:107–115PubMed Peterson HA (2005) Metallic implant removal in children. J Pediatr Orthop 25:107–115PubMed
29.
32.
go back to reference Savarino L, Greggi T, Martikos K, Lolli F, Greco M, Baldini N (2015) Long-term systemic metal distribution in patients with stainless steel spinal instrumentation. J Spinal Disord Tech 28:114–118CrossRefPubMed Savarino L, Greggi T, Martikos K, Lolli F, Greco M, Baldini N (2015) Long-term systemic metal distribution in patients with stainless steel spinal instrumentation. J Spinal Disord Tech 28:114–118CrossRefPubMed
33.
go back to reference Urban RM, Jacobs JJ, Tomlinson MJ, Gavrilovic J, Black J, Peoch M (2000) Dissemination of wear particles to the liver, spleen, and abdominal lymph nodes of patients with hip or knee replacement. J Bone Joint Surg Am 82:457–477CrossRefPubMed Urban RM, Jacobs JJ, Tomlinson MJ, Gavrilovic J, Black J, Peoch M (2000) Dissemination of wear particles to the liver, spleen, and abdominal lymph nodes of patients with hip or knee replacement. J Bone Joint Surg Am 82:457–477CrossRefPubMed
34.
go back to reference Rackham M, Cundy T, Antoniou G, Freeman BJC, Sutherland LM, Cundy PJ (2010) Predictors of serum chromium levels after stainless steel posterior spinal instrumentation for adolescent idiopathic scoliosis. Spine 35:975–982CrossRefPubMed Rackham M, Cundy T, Antoniou G, Freeman BJC, Sutherland LM, Cundy PJ (2010) Predictors of serum chromium levels after stainless steel posterior spinal instrumentation for adolescent idiopathic scoliosis. Spine 35:975–982CrossRefPubMed
36.
go back to reference Kim YJ, Kassab F, Berven SH et al (2005) Serum levels of nickel and chromium after instrumented posterior spinal arthrodesis. Spine 30:923–926CrossRefPubMed Kim YJ, Kassab F, Berven SH et al (2005) Serum levels of nickel and chromium after instrumented posterior spinal arthrodesis. Spine 30:923–926CrossRefPubMed
37.
go back to reference Cundy TP, Cundy WJ, Antoniou G, Sutherland LM, Freeman BJC, Cundy PJ (2014) Serum titanium, niobium, and aluminum levels two years following instrumented spinal fusion in children: does implant surface area predict serum metal ion levels? Eur Spine J 23:2393–2400. doi:10.1007/s00586-014-3279-x CrossRefPubMed Cundy TP, Cundy WJ, Antoniou G, Sutherland LM, Freeman BJC, Cundy PJ (2014) Serum titanium, niobium, and aluminum levels two years following instrumented spinal fusion in children: does implant surface area predict serum metal ion levels? Eur Spine J 23:2393–2400. doi:10.​1007/​s00586-014-3279-x CrossRefPubMed
40.
go back to reference Zeh A, Becker C, Planert M, Lattke P, Wohlrab D (2009) Time-dependent release of cobalt and chromium ions into the serum following implantation of the metal-on-metal Maverick type artificial lumbar disc. Arch Orthop Trauma Surg 129:741–746. doi:10.1007/s00402-008-0677-8 CrossRefPubMed Zeh A, Becker C, Planert M, Lattke P, Wohlrab D (2009) Time-dependent release of cobalt and chromium ions into the serum following implantation of the metal-on-metal Maverick type artificial lumbar disc. Arch Orthop Trauma Surg 129:741–746. doi:10.​1007/​s00402-008-0677-8 CrossRefPubMed
Metadata
Title
Corrosion of Harrington rod in idiopathic scoliosis: long-term effects
Authors
Beth Sherman
Tanya Crowell
Publication date
01-07-2018
Publisher
Springer Berlin Heidelberg
Published in
European Spine Journal / Issue Special Issue 3/2018
Print ISSN: 0940-6719
Electronic ISSN: 1432-0932
DOI
https://doi.org/10.1007/s00586-017-5183-7

Other articles of this Special Issue 3/2018

European Spine Journal 3/2018 Go to the issue