Skip to main content
Top
Published in: Current Reviews in Musculoskeletal Medicine 1/2016

01-03-2016 | Hip: Metal-on-Metal (J Cooper, Section Editor)

Diagnosis of adverse local tissue reactions following metal-on-metal hip arthroplasty

Authors: Brian P. Chalmers, Kevin I. Perry, Michael J. Taunton, Tad M. Mabry, Matthew P. Abdel

Published in: Current Reviews in Musculoskeletal Medicine | Issue 1/2016

Login to get access

Abstract

Metal-on-metal (MOM) bearing surfaces in hip arthroplasty have distinct advantages that led to the increase in popularity in North America in the early 2000s. However, with their increased use, concerns such as local cytotoxicity and hypersensitivity reactions leading to soft tissue damage and cystic mass formation (known collectively as adverse local tissue reactions (ALTR)) became apparent. The clinical presentation of ALTR is highly variable. The diagnosis of ALTR in MOM articulations in hip arthroplasty can be challenging and a combination of clinical presentation, physical examination, implant track record, component positioning, serum metal ion levels, cross-sectional imaging, histopathologic analysis, and consideration of alternative diagnoses are essential.
Literature
1.
go back to reference Fehring KA, Fehring TK. Modes of failure in metal-on-metal total hip arthroplasty. Orthop Clin North Am. 2015;46:185–92.CrossRefPubMed Fehring KA, Fehring TK. Modes of failure in metal-on-metal total hip arthroplasty. Orthop Clin North Am. 2015;46:185–92.CrossRefPubMed
2.
go back to reference Bozic KJ, Kurtz S, Lau E, Ong K, Chiu V, Vail TP, et al. The epidemiology of bearing surface usage in total hip arthroplasty in the United States. J Bone Joint Surg Am. 2009;91:1614–20.CrossRefPubMed Bozic KJ, Kurtz S, Lau E, Ong K, Chiu V, Vail TP, et al. The epidemiology of bearing surface usage in total hip arthroplasty in the United States. J Bone Joint Surg Am. 2009;91:1614–20.CrossRefPubMed
3.
go back to reference Jacobs JJ, Urban RM, Hallab NJ, Skipor AK, Fischer A, Wimmer MA. Metal-on-metal bearing surfaces. J Am Acad Orthop Surg. 2009;17:69–76.PubMed Jacobs JJ, Urban RM, Hallab NJ, Skipor AK, Fischer A, Wimmer MA. Metal-on-metal bearing surfaces. J Am Acad Orthop Surg. 2009;17:69–76.PubMed
4.
go back to reference Anissian HL, Stark A, Good V, Dahlstrand H, Clarke IC. The wear pattern in metal-on-metal hip prostheses. J Biomed Mater Res. 2001;58:673–8.CrossRefPubMed Anissian HL, Stark A, Good V, Dahlstrand H, Clarke IC. The wear pattern in metal-on-metal hip prostheses. J Biomed Mater Res. 2001;58:673–8.CrossRefPubMed
5.
go back to reference Kwon Y-M, Jacobs JJ, MacDonald SJ, Potter HG, Fehring TK, Lombardi AV. Evidence-based understanding of management perils for metal-on-metal hip arthroplasty patients. J Arthroplasty. 2012;27:20–5.CrossRefPubMed Kwon Y-M, Jacobs JJ, MacDonald SJ, Potter HG, Fehring TK, Lombardi AV. Evidence-based understanding of management perils for metal-on-metal hip arthroplasty patients. J Arthroplasty. 2012;27:20–5.CrossRefPubMed
6.•
go back to reference Nawabi DH, Nassif NA, Do HT, Stoner K, Elpers M, Su EP, et al. What causes unexplained pain in patients with metal-on metal hip devices? A retrieval, histologic, and imaging analysis. Clin Orthop Relat Res. 2014;472:543–54. This article analyzed the preoperative and intraoperative findings of patients with THAs with MOM articulations that were revised for unexplained pain. A high percentage of them had evidence of ALTR upon revision. Their conclusion was that with painful THAs with MOM articulations, ALTR should always be considered in the diagnostic algorithm. PubMedCentralCrossRefPubMed Nawabi DH, Nassif NA, Do HT, Stoner K, Elpers M, Su EP, et al. What causes unexplained pain in patients with metal-on metal hip devices? A retrieval, histologic, and imaging analysis. Clin Orthop Relat Res. 2014;472:543–54. This article analyzed the preoperative and intraoperative findings of patients with THAs with MOM articulations that were revised for unexplained pain. A high percentage of them had evidence of ALTR upon revision. Their conclusion was that with painful THAs with MOM articulations, ALTR should always be considered in the diagnostic algorithm. PubMedCentralCrossRefPubMed
7.•
go back to reference Berry DJ, Abdel MP, Callaghan JJ. What are the current clinical issues in wear and tribocorrosion? Clin Orthop Relat Res. 2014;3659–64. This article presents an excellent review of current diagnostic and treatment strategies for wear and corrosion. More importantly, it also highlights critical areas for which improvement in wear properties, diagnosis, management, and treatment can be made. Berry DJ, Abdel MP, Callaghan JJ. What are the current clinical issues in wear and tribocorrosion? Clin Orthop Relat Res. 2014;3659–64. This article presents an excellent review of current diagnostic and treatment strategies for wear and corrosion. More importantly, it also highlights critical areas for which improvement in wear properties, diagnosis, management, and treatment can be made.
8.
go back to reference Natu S, Sidaginamale RP, Gandhi J, Langton DJ, Nargola VF. Adverse reactions to metal debris: histopathological features of periprosthetic soft tissue reactions seen in association with failed metal on metal hip arthroplasties. J Clin Pathol. 2012;65:409–18.CrossRefPubMed Natu S, Sidaginamale RP, Gandhi J, Langton DJ, Nargola VF. Adverse reactions to metal debris: histopathological features of periprosthetic soft tissue reactions seen in association with failed metal on metal hip arthroplasties. J Clin Pathol. 2012;65:409–18.CrossRefPubMed
9.
go back to reference Hayter CL, Gold SL, Koff MF, Perino G, Nawabi DH, Miller TT, et al. MRI findings in painful metal-on-metal hip arthroplasty. Am J Roentgenol. 2012;199:884–93.CrossRef Hayter CL, Gold SL, Koff MF, Perino G, Nawabi DH, Miller TT, et al. MRI findings in painful metal-on-metal hip arthroplasty. Am J Roentgenol. 2012;199:884–93.CrossRef
10.
go back to reference Hauptfleisch J, Pandit H, Grammatopoulos G, Gill HS, Murray DW, Ostlere S. A MRI classification of periprosthetic soft tissue masses (pseudotumours) associated with metal-on-metal resurfacing hip arthroplasty. Skelet Radiol. 2012;41:149–55.CrossRef Hauptfleisch J, Pandit H, Grammatopoulos G, Gill HS, Murray DW, Ostlere S. A MRI classification of periprosthetic soft tissue masses (pseudotumours) associated with metal-on-metal resurfacing hip arthroplasty. Skelet Radiol. 2012;41:149–55.CrossRef
11.•
go back to reference Kwon Y, Lombardi AV, Jacobs JJ, Fehring TK, Lewis CG, Cabanela ME. Risk stratification algorithm for management of patients with metal-on-metal hip arthroplasty: consensus statement of the American Association of Hip and Knee Surgeons, the American Academy of Orthopaedic Surgeons, and the Hip Society. J Bone Joint Surg Am. 2014;96(1):e4. doi:10.2106/JBJS.M.00160. This study outlines the consensus statement by the Hip Society, AAOS, and AAHKS on the diagnostic algorithm in symptomatic and asymptomatic patients with MOM articulations in THA. It incorporates all of the diagnostic factors considered in this review. Kwon Y, Lombardi AV, Jacobs JJ, Fehring TK, Lewis CG, Cabanela ME. Risk stratification algorithm for management of patients with metal-on-metal hip arthroplasty: consensus statement of the American Association of Hip and Knee Surgeons, the American Academy of Orthopaedic Surgeons, and the Hip Society. J Bone Joint Surg Am. 2014;96(1):e4. doi:10.​2106/​JBJS.​M.​00160. This study outlines the consensus statement by the Hip Society, AAOS, and AAHKS on the diagnostic algorithm in symptomatic and asymptomatic patients with MOM articulations in THA. It incorporates all of the diagnostic factors considered in this review.
12.
go back to reference Grammatopoulos G, Pandit H, Orth F, Kamali A, Maggiani F, Athanasou N. The correlation of wear with histological features. J Bone Joint Surg Am. 2013;81:1–10. Grammatopoulos G, Pandit H, Orth F, Kamali A, Maggiani F, Athanasou N. The correlation of wear with histological features. J Bone Joint Surg Am. 2013;81:1–10.
13.
go back to reference Campbell P, Ebramzadeh E, Nelson S, Takamura K, De Smet K, Amstutz HC. Histological features of pseudotumor-like tissues from metal-on-metal hips. Clin Orthop Relat Res. 2010;468:2321–7.PubMedCentralCrossRefPubMed Campbell P, Ebramzadeh E, Nelson S, Takamura K, De Smet K, Amstutz HC. Histological features of pseudotumor-like tissues from metal-on-metal hips. Clin Orthop Relat Res. 2010;468:2321–7.PubMedCentralCrossRefPubMed
14.
go back to reference Tharani R, Dorey FJ, Schmalzried TP. The risk of cancer following total hip or knee arthroplasty. J Bone Joint Surg Am. 2001;83-A:774–80.PubMed Tharani R, Dorey FJ, Schmalzried TP. The risk of cancer following total hip or knee arthroplasty. J Bone Joint Surg Am. 2001;83-A:774–80.PubMed
15.
go back to reference Tower SS. Arthroprosthetic cobaltism: neurological and cardiac manifestations in two patients with metal-on-metal arthroplasty: a case report. J Bone Joint Surg Am. 2010;92:2847–51. Tower SS. Arthroprosthetic cobaltism: neurological and cardiac manifestations in two patients with metal-on-metal arthroplasty: a case report. J Bone Joint Surg Am. 2010;92:2847–51.
16.•
go back to reference Lombardi Jr AV, Barrack RL, Berend KR, Cuckler JM, Jacobs JJ, Mont MA, et al. The Hip Society: algorithmic approach to diagnosis and management of metal-on-metal arthroplasty. J Bone Joint Surg Br. 2012;94-B:14–8. This study outlines the consensus statement by the Hip Society, AAOS, and AAHKS on the diagnostic algorithm in symptomatic and asymptomatic patients with MOM articulations in THA. It incorporates all of the diagnostic factors considered in this review. CrossRef Lombardi Jr AV, Barrack RL, Berend KR, Cuckler JM, Jacobs JJ, Mont MA, et al. The Hip Society: algorithmic approach to diagnosis and management of metal-on-metal arthroplasty. J Bone Joint Surg Br. 2012;94-B:14–8. This study outlines the consensus statement by the Hip Society, AAOS, and AAHKS on the diagnostic algorithm in symptomatic and asymptomatic patients with MOM articulations in THA. It incorporates all of the diagnostic factors considered in this review. CrossRef
17.•
go back to reference Kwon YM, Ostlere SJ, McLardy-Smith P, Athanasou NA, Gill HS, Murray DW. “Asymptomatic” pseudotumors after metal-on-metal hip resurfacing arthroplasty. Prevalence and metal ion study. J Arthroplasty. 2011;26:511–8. This study screened patients for ALTR, specifically pseudotumors, by US and metal ion levels to analyze not only the incidence of symptomatic and asymptomatic pseudotumors but also to correlate pseudotumors with elevated metal ion levels. This article showed that ALTR may have higher metal ion levels and that not all ALTR, even large pseudotumors, are symptomatic. CrossRefPubMed Kwon YM, Ostlere SJ, McLardy-Smith P, Athanasou NA, Gill HS, Murray DW. “Asymptomatic” pseudotumors after metal-on-metal hip resurfacing arthroplasty. Prevalence and metal ion study. J Arthroplasty. 2011;26:511–8. This study screened patients for ALTR, specifically pseudotumors, by US and metal ion levels to analyze not only the incidence of symptomatic and asymptomatic pseudotumors but also to correlate pseudotumors with elevated metal ion levels. This article showed that ALTR may have higher metal ion levels and that not all ALTR, even large pseudotumors, are symptomatic. CrossRefPubMed
19.
go back to reference Hart AJ, Sabah SA, Bandi AS, Maggiore P, Tarassoli P, Sampson B, et al. Sensitivity and specificity of blood cobalt and chromium metal ions for predicting failure of metal-on-metal hip replacement. J Bone Joint Surg Br. 2011;93-B:1308–13.CrossRef Hart AJ, Sabah SA, Bandi AS, Maggiore P, Tarassoli P, Sampson B, et al. Sensitivity and specificity of blood cobalt and chromium metal ions for predicting failure of metal-on-metal hip replacement. J Bone Joint Surg Br. 2011;93-B:1308–13.CrossRef
20.
go back to reference Pajam KJJ. Surveillance of patients with metal-on-metal hip resurfacing and total hip prostheses. J Bone Join Surg Am. 2014;96(13):1091–9.CrossRef Pajam KJJ. Surveillance of patients with metal-on-metal hip resurfacing and total hip prostheses. J Bone Join Surg Am. 2014;96(13):1091–9.CrossRef
21.
go back to reference Bartelt RB, Yuan BJ, Trousdale RT, Sierra RJ. The prevalence of groin pain after metal-on-metal total hip arthroplasty and total hip resurfacing. Clin Orthop Relat Res. 2010;468:2346–56.PubMedCentralCrossRefPubMed Bartelt RB, Yuan BJ, Trousdale RT, Sierra RJ. The prevalence of groin pain after metal-on-metal total hip arthroplasty and total hip resurfacing. Clin Orthop Relat Res. 2010;468:2346–56.PubMedCentralCrossRefPubMed
22.
go back to reference De Haan R, Pattyn C, Gill HS, Murray DW, Campbell PA, De Smet K. Correlation between inclination of the acetabular component and metal ion levels in metal-on-metal hip resurfacing replacement. J Bone Joint Surg Br. 2008;90:1291–7.CrossRefPubMed De Haan R, Pattyn C, Gill HS, Murray DW, Campbell PA, De Smet K. Correlation between inclination of the acetabular component and metal ion levels in metal-on-metal hip resurfacing replacement. J Bone Joint Surg Br. 2008;90:1291–7.CrossRefPubMed
23.•
go back to reference Wyles CC, Larson DR, Houdek MT, Sierra RJ, Trousdale RT. Utility of synovial fluid aspirations in failed metal-on-metal total hip arthroplasty. J Arthroplasty. 2013;28:818–23. This study was one of the first studies to further analyze the diagnosis of infection in the presence of an ALTR from a MOM articulation. The traditional diagnostic factors (CRP, ESR, and synovial testing) must be carefully scrutinized in the presence of an inflammatory response from an ALTR. CrossRefPubMed Wyles CC, Larson DR, Houdek MT, Sierra RJ, Trousdale RT. Utility of synovial fluid aspirations in failed metal-on-metal total hip arthroplasty. J Arthroplasty. 2013;28:818–23. This study was one of the first studies to further analyze the diagnosis of infection in the presence of an ALTR from a MOM articulation. The traditional diagnostic factors (CRP, ESR, and synovial testing) must be carefully scrutinized in the presence of an inflammatory response from an ALTR. CrossRefPubMed
24.
go back to reference Cobb JP, Davda K, Ahmad A, Harris SJ, Masjedi M, Hart AJ. Why large-head metal-on-metal hip replacements are painful: the anatomical basis of psoas impingement on the femoral head-neck junction. J Bone Joint Surg Br. 2011;93:881–5.CrossRefPubMed Cobb JP, Davda K, Ahmad A, Harris SJ, Masjedi M, Hart AJ. Why large-head metal-on-metal hip replacements are painful: the anatomical basis of psoas impingement on the femoral head-neck junction. J Bone Joint Surg Br. 2011;93:881–5.CrossRefPubMed
25.
go back to reference Engh CA, Macdonald SJ, Sritulanondha S, Korczak A, Naudie D. Metal ion levels after metal-on-metal total hip arthroplasty: a five-year, prospective randomized trial. J Bone Joint Surg Am. 2014;96:448–55.CrossRefPubMed Engh CA, Macdonald SJ, Sritulanondha S, Korczak A, Naudie D. Metal ion levels after metal-on-metal total hip arthroplasty: a five-year, prospective randomized trial. J Bone Joint Surg Am. 2014;96:448–55.CrossRefPubMed
26.
go back to reference Engh CA, MacDonald SJ, Sritulanondha S, Thompson A, Naudie D, Engh CA. 2008 John Charnley award: metal ion levels after metal-on-metal total hip arthroplasty: a randomized trial. Clin Orthop Relat Res. 2009;467:101–11.PubMedCentralCrossRefPubMed Engh CA, MacDonald SJ, Sritulanondha S, Thompson A, Naudie D, Engh CA. 2008 John Charnley award: metal ion levels after metal-on-metal total hip arthroplasty: a randomized trial. Clin Orthop Relat Res. 2009;467:101–11.PubMedCentralCrossRefPubMed
27.•
go back to reference Levine BR, Hsu AR, Skipor AK, Hallab NJ, Paprosky WG, Galante JO, et al. Ten-year outcome of serum metal ion levels after primary total hip arthroplasty: a concise follow-up of a previous report*. J Bone Joint Surg Am. 2013;95:512–8. These series of studies showed that metal ion levels are elevated in MOM articulations in THAs. Further, it shows that metal ion levels increase over time, especially with larger femoral head sizes. PubMedCentralCrossRefPubMed Levine BR, Hsu AR, Skipor AK, Hallab NJ, Paprosky WG, Galante JO, et al. Ten-year outcome of serum metal ion levels after primary total hip arthroplasty: a concise follow-up of a previous report*. J Bone Joint Surg Am. 2013;95:512–8. These series of studies showed that metal ion levels are elevated in MOM articulations in THAs. Further, it shows that metal ion levels increase over time, especially with larger femoral head sizes. PubMedCentralCrossRefPubMed
28.
go back to reference Fehring TK, Carter JL, Fehring KA, Odum SM, Griffin WL. Cobalt to chromium ratio is not a key marker for altr in metal on metal hips. J Arthroplasty. 2015;30(9 Suppl):107–9.CrossRefPubMed Fehring TK, Carter JL, Fehring KA, Odum SM, Griffin WL. Cobalt to chromium ratio is not a key marker for altr in metal on metal hips. J Arthroplasty. 2015;30(9 Suppl):107–9.CrossRefPubMed
29.
go back to reference Della Valle C, Parvizi J, Bauer TW, DiCesare PE, Evans RP, Segreti J, et al. American Academy of Orthopaedic Surgeons clinical practice guideline on: the diagnosis of periprosthetic joint infections of the hip and knee. J Bone Joint Surg Am. 2011;93:1355–7.CrossRefPubMed Della Valle C, Parvizi J, Bauer TW, DiCesare PE, Evans RP, Segreti J, et al. American Academy of Orthopaedic Surgeons clinical practice guideline on: the diagnosis of periprosthetic joint infections of the hip and knee. J Bone Joint Surg Am. 2011;93:1355–7.CrossRefPubMed
30.
go back to reference Berbari E, Mabry T, Tsaras G, Spangehl M, Erwin PJ, Murad MH, et al. Inflammatory blood laboratory levels as markers of prosthetic joint infection: a systematic review and meta-analysis. J Bone Joint Surg Am. 2010;92:2102–9.CrossRefPubMed Berbari E, Mabry T, Tsaras G, Spangehl M, Erwin PJ, Murad MH, et al. Inflammatory blood laboratory levels as markers of prosthetic joint infection: a systematic review and meta-analysis. J Bone Joint Surg Am. 2010;92:2102–9.CrossRefPubMed
31.
go back to reference Spangehl MJ, Masri BA, O’Connell JX. Duncan CP prospective analysis of preoperative and intraoperative investigations for the diagnosis of infection at the sites of two hundred and two revision total hip arthroplasties. J Bone Joint Surg Am. 1999;81:672–83.PubMed Spangehl MJ, Masri BA, O’Connell JX. Duncan CP prospective analysis of preoperative and intraoperative investigations for the diagnosis of infection at the sites of two hundred and two revision total hip arthroplasties. J Bone Joint Surg Am. 1999;81:672–83.PubMed
32.
go back to reference Yi PH, Cross MB, Moric M, Levine BR, Sporer SM, Paprosky WG, et al. Do serologic and synovial tests help diagnose infection in revision hip arthroplasty with metal-on-metal bearings or corrosion? Clin Orthop Relat Res. 2014;473:498–505.PubMedCentralCrossRef Yi PH, Cross MB, Moric M, Levine BR, Sporer SM, Paprosky WG, et al. Do serologic and synovial tests help diagnose infection in revision hip arthroplasty with metal-on-metal bearings or corrosion? Clin Orthop Relat Res. 2014;473:498–505.PubMedCentralCrossRef
33.
go back to reference Liddle AD, Sabah SA, Mcrobbie D, Henckel J, Cobb JP, Skinner JA, et al. Pseudotumors in association with well-functioning metal-on-metal hip prostheses. J Bone Joint Surg Am. 2012;94:317–25.PubMed Liddle AD, Sabah SA, Mcrobbie D, Henckel J, Cobb JP, Skinner JA, et al. Pseudotumors in association with well-functioning metal-on-metal hip prostheses. J Bone Joint Surg Am. 2012;94:317–25.PubMed
34.
go back to reference Mikhael MM, Hanssen AD, Sierra RJ. Failure of metal-on-metal total hip arthroplasty mimicking hip infection. A report of two cases. J Bone Joint Surg Am. 2009;91:443–6.CrossRefPubMed Mikhael MM, Hanssen AD, Sierra RJ. Failure of metal-on-metal total hip arthroplasty mimicking hip infection. A report of two cases. J Bone Joint Surg Am. 2009;91:443–6.CrossRefPubMed
35.
go back to reference Wyles CC, Van Demark RE, Sierra RJ, Trousdale RT. High rate of infection after aseptic revision of failed metal-on-metal total hip arthroplasty. Clin Orthop Relat Res. 2014;472:509–16.PubMedCentralCrossRefPubMed Wyles CC, Van Demark RE, Sierra RJ, Trousdale RT. High rate of infection after aseptic revision of failed metal-on-metal total hip arthroplasty. Clin Orthop Relat Res. 2014;472:509–16.PubMedCentralCrossRefPubMed
36.
go back to reference Kwon YM. Cross-sectional imaging in evaluation of soft tissue reactions secondary to metal debris. J Arthroplasty. 2014;29:653–6.CrossRefPubMed Kwon YM. Cross-sectional imaging in evaluation of soft tissue reactions secondary to metal debris. J Arthroplasty. 2014;29:653–6.CrossRefPubMed
37.•
go back to reference Nam D, Barrack RL, Potter HG. What are the advantages and disadvantages of imaging modalities to diagnose wear-related corrosion problems? Clin Orthop Relat Res. 2014;3665–73. This article provides an excellent overview of cross-sectional imaging modalities utilized to screen and diagnose ALTR in MOM articulations in THA. It is an excellent discussion with up-to-date research referenced that analyzes the advantages and disadvantages of US, CT, and MRI. Nam D, Barrack RL, Potter HG. What are the advantages and disadvantages of imaging modalities to diagnose wear-related corrosion problems? Clin Orthop Relat Res. 2014;3665–73. This article provides an excellent overview of cross-sectional imaging modalities utilized to screen and diagnose ALTR in MOM articulations in THA. It is an excellent discussion with up-to-date research referenced that analyzes the advantages and disadvantages of US, CT, and MRI.
38.
go back to reference Nishii T, Sakai T, Takao M, Yoshikawa H, Sugano N. Is ultrasound screening reliable for adverse local tissue reaction after hip arthroplasty? J Arthroplasty. 2014;29:2239–44.CrossRefPubMed Nishii T, Sakai T, Takao M, Yoshikawa H, Sugano N. Is ultrasound screening reliable for adverse local tissue reaction after hip arthroplasty? J Arthroplasty. 2014;29:2239–44.CrossRefPubMed
39.
go back to reference Nishii T, Sakai T, Takao M, Yoshikawa H, Sugano N. Ultrasound screening of periarticular soft tissue abnormality around metal-on-metal bearings. J Arthroplasty. 2012;27:895–900.CrossRefPubMed Nishii T, Sakai T, Takao M, Yoshikawa H, Sugano N. Ultrasound screening of periarticular soft tissue abnormality around metal-on-metal bearings. J Arthroplasty. 2012;27:895–900.CrossRefPubMed
40.
go back to reference Muraoka K, Naito M, Nakamura Y, Hagio T, Takano K. Usefulness of ultrasonography for detection of pseudotumors after metal-on-metal total hip arthroplasty. J Arthroplasty. 2014;30:879–84.CrossRefPubMed Muraoka K, Naito M, Nakamura Y, Hagio T, Takano K. Usefulness of ultrasonography for detection of pseudotumors after metal-on-metal total hip arthroplasty. J Arthroplasty. 2014;30:879–84.CrossRefPubMed
41.
go back to reference Siddiqui IA, Sabah SA, Satchithananda K, Lim AK, Cro S, Henckel J, et al. A comparison of the diagnostic accuracy of MARS MRI and ultrasound of the painful metal-on-metal hip arthroplasty. Acta Orthop. 2014;85:1–8.CrossRef Siddiqui IA, Sabah SA, Satchithananda K, Lim AK, Cro S, Henckel J, et al. A comparison of the diagnostic accuracy of MARS MRI and ultrasound of the painful metal-on-metal hip arthroplasty. Acta Orthop. 2014;85:1–8.CrossRef
42.
go back to reference Anderson H, Toms AP, Cahir JG, Goodwin RW, Wimhurst J, Nolan JF. Grading the severity of soft tissue changes associated with metal-on-metal hip replacements: reliability of an MR grading system. Skelet Radiol. 2011;40:303–7.CrossRef Anderson H, Toms AP, Cahir JG, Goodwin RW, Wimhurst J, Nolan JF. Grading the severity of soft tissue changes associated with metal-on-metal hip replacements: reliability of an MR grading system. Skelet Radiol. 2011;40:303–7.CrossRef
43.
go back to reference Nawabi DH, Gold S, Lyman S, Fields K, Padgett DE, Potter HG. MRI predicts ALVAL and tissue damage in metal-on-metal hip arthroplasty. Clin Orthop Relat Res. 2014;472:471–81.PubMedCentralCrossRefPubMed Nawabi DH, Gold S, Lyman S, Fields K, Padgett DE, Potter HG. MRI predicts ALVAL and tissue damage in metal-on-metal hip arthroplasty. Clin Orthop Relat Res. 2014;472:471–81.PubMedCentralCrossRefPubMed
44.
go back to reference Ibanez HE, Grand MG, Meredith TA, Wippold FJ. Magnetic resonance imaging findings in Vogt-Koyanagi-Harada syndrome. Retina. 1994;14:164–8.CrossRefPubMed Ibanez HE, Grand MG, Meredith TA, Wippold FJ. Magnetic resonance imaging findings in Vogt-Koyanagi-Harada syndrome. Retina. 1994;14:164–8.CrossRefPubMed
Metadata
Title
Diagnosis of adverse local tissue reactions following metal-on-metal hip arthroplasty
Authors
Brian P. Chalmers
Kevin I. Perry
Michael J. Taunton
Tad M. Mabry
Matthew P. Abdel
Publication date
01-03-2016
Publisher
Springer US
Published in
Current Reviews in Musculoskeletal Medicine / Issue 1/2016
Electronic ISSN: 1935-9748
DOI
https://doi.org/10.1007/s12178-016-9321-3

Other articles of this Issue 1/2016

Current Reviews in Musculoskeletal Medicine 1/2016 Go to the issue

Shoulder Arthroplasty (G Athwal, Section Editor)

The arthritic glenoid: anatomy and arthroplasty designs