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Published in: European Spine Journal 5/2016

01-05-2016 | Review Article

Spinal metallosis: a systematic review

Authors: Yoni Goldenberg, Jin W. Tee, Cesar M. Salinas-La Rosa, Michael Murphy

Published in: European Spine Journal | Issue 5/2016

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Abstract

Purpose

To document a rarely reported complication associated with spinal instrumentation and to evaluate the current literature on spinal metallosis and spinal metalloma.

Methods

A local case report is presented. EBSCOhost, PubMed and ScienceDirect databases were used to conduct a systematic review for articles describing spinal metallosis and spinal metalloma.

Results

A total of 836 articles were identified using the terms “metalloma” or “metallosis”. Exclusion of arthroplasty-related abstracts retrieved 46 articles of which 3 full text articles presenting spinal metalloma as a causative pathological finding responsible for neurological signs and symptoms in patients with previous spinal fusion instrumentation were reviewed. Our case is the first described with titanium-composed posterior instrumentation and fifth reported, demonstrating the phenomena of neurological symptoms and signs attributed directly to neural tissue compression by spinal metalloma after spinal instrumentation.

Conclusion

Spinal metallosis can present weeks to years after spinal instrumentation surgery and is a potential cause of neural compression. This process appears to be independent of the instrument composition as metallosis has now been demonstrated in both titanium and stainless steel constructs.
Literature
1.
go back to reference Harrington PR (1962) Treatment of scoliosis. Correction and internal fixation by spine instrumentation. J Bone Joint Surg Am 44:591–610PubMed Harrington PR (1962) Treatment of scoliosis. Correction and internal fixation by spine instrumentation. J Bone Joint Surg Am 44:591–610PubMed
2.
go back to reference Bago J, Ramirez M, Pellise F et al (2003) Survivorship analysis of Cotrel–Dubousset instrumentation in idiopathic scoliosis. Eur Spine J 12:435–439CrossRefPubMedPubMedCentral Bago J, Ramirez M, Pellise F et al (2003) Survivorship analysis of Cotrel–Dubousset instrumentation in idiopathic scoliosis. Eur Spine J 12:435–439CrossRefPubMedPubMedCentral
3.
go back to reference Fernandez-Baillo N, Sanchez JMS, Gallego EC et al (2012) Intraspinal metalloma causing lumbar stenosis after interbody fusion with cylindrical cages. Acta Orthop Belg 78:811–814PubMed Fernandez-Baillo N, Sanchez JMS, Gallego EC et al (2012) Intraspinal metalloma causing lumbar stenosis after interbody fusion with cylindrical cages. Acta Orthop Belg 78:811–814PubMed
4.
go back to reference Francois J, Coessens R, Lauweryns P (2007) Early removal of a Maverick disc prosthesis: surgical findings and morphological changes. Acta Orthop Belg 73:122–127PubMed Francois J, Coessens R, Lauweryns P (2007) Early removal of a Maverick disc prosthesis: surgical findings and morphological changes. Acta Orthop Belg 73:122–127PubMed
5.
go back to reference Guyer RD, Shellock J, Maclennan B et al (2011) Early failure of metal-on-metal artificial disc prostheses associated with lymphocytic reaction: diagnosis and treatment experience in four cases. Spine 36:E492–E497CrossRefPubMed Guyer RD, Shellock J, Maclennan B et al (2011) Early failure of metal-on-metal artificial disc prostheses associated with lymphocytic reaction: diagnosis and treatment experience in four cases. Spine 36:E492–E497CrossRefPubMed
6.
go back to reference Takahashi S, Delecrin J, Passuti N (2001) Intraspinal metallosis causing delayed neurologic symptoms after spinal instrumentation surgery. Spine 26:1495–1498CrossRefPubMed Takahashi S, Delecrin J, Passuti N (2001) Intraspinal metallosis causing delayed neurologic symptoms after spinal instrumentation surgery. Spine 26:1495–1498CrossRefPubMed
7.
go back to reference Tezer M, Kuzgun U, Hamzaoglu A et al (2005) Intraspinal metalloma resulting in late paraparesis. Arch Orthop Trauma Surg 125:417–421CrossRefPubMed Tezer M, Kuzgun U, Hamzaoglu A et al (2005) Intraspinal metalloma resulting in late paraparesis. Arch Orthop Trauma Surg 125:417–421CrossRefPubMed
8.
go back to reference Black J, Sherk H, Bonini J et al (1990) Metallosis associated with a stable titanium-alloy femoral component in total hip replacement: a case report. J Bone Joint Surg Am 72:126–130PubMed Black J, Sherk H, Bonini J et al (1990) Metallosis associated with a stable titanium-alloy femoral component in total hip replacement: a case report. J Bone Joint Surg Am 72:126–130PubMed
9.
go back to reference Korovessis P, Ptsinis G, Repanti M et al (2006) Metallosis after contemporary metal-on-metal total hip arthroplasty. Five to nine-year follow up. J Bone Joint Surg 88-A:1183–1191CrossRef Korovessis P, Ptsinis G, Repanti M et al (2006) Metallosis after contemporary metal-on-metal total hip arthroplasty. Five to nine-year follow up. J Bone Joint Surg 88-A:1183–1191CrossRef
10.
go back to reference Matziolis G, Perka C, Disch A (2003) Massive metallosis after revision of a fractured ceramic head onto a metal head. Arch Orthop Trauma Surg 123:48–50PubMed Matziolis G, Perka C, Disch A (2003) Massive metallosis after revision of a fractured ceramic head onto a metal head. Arch Orthop Trauma Surg 123:48–50PubMed
11.
go back to reference Sanchis-Alfonso V (2007) Severe metallosis after unicompartmental knee arthroplasty. Knee Surg Sports Traumatol Arthrosc 15:361–364CrossRefPubMed Sanchis-Alfonso V (2007) Severe metallosis after unicompartmental knee arthroplasty. Knee Surg Sports Traumatol Arthrosc 15:361–364CrossRefPubMed
12.
go back to reference Berguiristain J, Del Rio J, Duart J et al (2006) Corrosion and late infection causing delayed paraparesis after spinal instrumentation. J Pediatr Orthop B 15:320–323CrossRef Berguiristain J, Del Rio J, Duart J et al (2006) Corrosion and late infection causing delayed paraparesis after spinal instrumentation. J Pediatr Orthop B 15:320–323CrossRef
13.
go back to reference Clark CR, Shufflebarger HL (1999) Late developing infection in instrumented idiopathic scoliosis. Spine 24:1909–1912CrossRefPubMed Clark CR, Shufflebarger HL (1999) Late developing infection in instrumented idiopathic scoliosis. Spine 24:1909–1912CrossRefPubMed
14.
go back to reference Jacobs JJ, Gilberte JL, Urban RM (1998) Corrosion of metal orthpaedic implants. J Bone Joint Surg 80-A:268–282 Jacobs JJ, Gilberte JL, Urban RM (1998) Corrosion of metal orthpaedic implants. J Bone Joint Surg 80-A:268–282
15.
go back to reference Pienkowski D, Stephens GC, Doers TM et al (1998) Multicycle mechanical performance of titanmium and stainless steel transpendicular spine implants. Spine 23:782–788CrossRefPubMed Pienkowski D, Stephens GC, Doers TM et al (1998) Multicycle mechanical performance of titanmium and stainless steel transpendicular spine implants. Spine 23:782–788CrossRefPubMed
17.
go back to reference Muschik M, Luck W, Schlenzka D (2004) Implant removal for late-developing infection after instrumented posterior spinal fusion for scoliosis: reinstrumentation reduces loss of correction. A retrospective analysis of 45 cases. Eur Spine J 13:645–651CrossRefPubMedPubMedCentral Muschik M, Luck W, Schlenzka D (2004) Implant removal for late-developing infection after instrumented posterior spinal fusion for scoliosis: reinstrumentation reduces loss of correction. A retrospective analysis of 45 cases. Eur Spine J 13:645–651CrossRefPubMedPubMedCentral
18.
go back to reference Waelchli B, Min K, Cathrein P et al (2002) Vertebral body compression fracture after removal of pedicle screws: a report of two cases. Eur Spine J 11:504–506CrossRefPubMedPubMedCentral Waelchli B, Min K, Cathrein P et al (2002) Vertebral body compression fracture after removal of pedicle screws: a report of two cases. Eur Spine J 11:504–506CrossRefPubMedPubMedCentral
19.
go back to reference Akazawa T, Minami S, Takahashi K et al (2005) Corrosion of spinal implants retrieved from patients with scoliosis. J Orthop Sci 10:200–205CrossRefPubMed Akazawa T, Minami S, Takahashi K et al (2005) Corrosion of spinal implants retrieved from patients with scoliosis. J Orthop Sci 10:200–205CrossRefPubMed
20.
go back to reference Aulisa L, Di Benedetto A, Vinciguerra A et al (1982) Corrosion of the Harrington’s instrumentation and biological behavior of the rod-human spine system. Biomaterials 3:246–248CrossRefPubMed Aulisa L, Di Benedetto A, Vinciguerra A et al (1982) Corrosion of the Harrington’s instrumentation and biological behavior of the rod-human spine system. Biomaterials 3:246–248CrossRefPubMed
21.
go back to reference Bono C, Lee C (2004) Critical analysis of trends in fusion for degenerative disc disease over the past 20 years: influence of technique on fusion rate and clinical outcome. Spine 29:455–463CrossRefPubMed Bono C, Lee C (2004) Critical analysis of trends in fusion for degenerative disc disease over the past 20 years: influence of technique on fusion rate and clinical outcome. Spine 29:455–463CrossRefPubMed
22.
go back to reference Fritzell P, Hagg O, Wessberg P et al (2002) Chronic low back pain and fusion: a comparison of three surgical techniques: a prospective multicenter randomized study from the Swedish lumbar spine study group. Spine (Phila Pa 1976) 27:1131–1141CrossRef Fritzell P, Hagg O, Wessberg P et al (2002) Chronic low back pain and fusion: a comparison of three surgical techniques: a prospective multicenter randomized study from the Swedish lumbar spine study group. Spine (Phila Pa 1976) 27:1131–1141CrossRef
23.
go back to reference Kapur RA, Amirfeyz R, Wylde V et al (2010) Clinical outcomes and fusion success associated with the use of BoneSave in spinal surgery. Arch Orthop Trauma Surg 130:641–647CrossRefPubMed Kapur RA, Amirfeyz R, Wylde V et al (2010) Clinical outcomes and fusion success associated with the use of BoneSave in spinal surgery. Arch Orthop Trauma Surg 130:641–647CrossRefPubMed
24.
go back to reference Kim YJ, Kassab F, Berven SH et al (2005) Serum levels of nickel and chromium after instrumented posterior arthrodesis. Spine 30:923–926CrossRefPubMed Kim YJ, Kassab F, Berven SH et al (2005) Serum levels of nickel and chromium after instrumented posterior arthrodesis. Spine 30:923–926CrossRefPubMed
Metadata
Title
Spinal metallosis: a systematic review
Authors
Yoni Goldenberg
Jin W. Tee
Cesar M. Salinas-La Rosa
Michael Murphy
Publication date
01-05-2016
Publisher
Springer Berlin Heidelberg
Published in
European Spine Journal / Issue 5/2016
Print ISSN: 0940-6719
Electronic ISSN: 1432-0932
DOI
https://doi.org/10.1007/s00586-015-4347-6

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