Skip to main content
Top
Published in: Journal of Neurology 3/2021

Open Access 01-03-2021 | Parkinson's Disease | Review

Language impairment in progressive supranuclear palsy and corticobasal syndrome

Authors: Katie A. Peterson, Karalyn Patterson, James B. Rowe

Published in: Journal of Neurology | Issue 3/2021

Login to get access

Abstract

Although commonly known as movement disorders, progressive supranuclear palsy (PSP) and corticobasal syndrome (CBS) may present with changes in speech and language alongside or even before motor symptoms. The differential diagnosis of these two disorders can be challenging, especially in the early stages. Here we review their impact on speech and language. We discuss the neurobiological and clinical-phenomenological overlap of PSP and CBS with each other, and with other disorders including non-fluent agrammatic primary progressive aphasia and primary progressive apraxia of speech. Because language impairment is often an early and persistent problem in CBS and PSP, there is a need for improved methods for language screening in primary and secondary care, and more detailed language assessments in tertiary healthcare settings. Improved language assessment may aid differential diagnosis as well as inform clinical management decisions.
Literature
4.
go back to reference Josephs KA, Hodges JR, Snowden JS et al (2011) Neuropathological background of phenotypical variability in frontotemporal dementia. Acta Neuropathol 122:137–153CrossRef Josephs KA, Hodges JR, Snowden JS et al (2011) Neuropathological background of phenotypical variability in frontotemporal dementia. Acta Neuropathol 122:137–153CrossRef
12.
go back to reference Lang AE, Riley DE, Bergeron C (1994) Cortical-basal ganglionic degeneration. In: Calne DB (ed) Neurodegenerative diseases. Saunders, Philadelphia, pp 877–894 Lang AE, Riley DE, Bergeron C (1994) Cortical-basal ganglionic degeneration. In: Calne DB (ed) Neurodegenerative diseases. Saunders, Philadelphia, pp 877–894
27.
go back to reference Riley DE, Lang AE (1988) Corticobasal ganglionic degeneration (CBGD): further observations in six additional cases (abstract). Neurology 38:360CrossRef Riley DE, Lang AE (1988) Corticobasal ganglionic degeneration (CBGD): further observations in six additional cases (abstract). Neurology 38:360CrossRef
44.
go back to reference Sakai K, Furui E, Komai K et al (2002) Acquired stuttering as an early symptom in a patient with progressive supranuclear palsy. Rinsho Shinkeigaku 42:178–180PubMed Sakai K, Furui E, Komai K et al (2002) Acquired stuttering as an early symptom in a patient with progressive supranuclear palsy. Rinsho Shinkeigaku 42:178–180PubMed
67.
go back to reference Grafman J, Litvan I, Gomez C, Chase TN (1990) Frontal lobe function in progressive supranuclear palsy. Arch Neurol 47:553–558CrossRef Grafman J, Litvan I, Gomez C, Chase TN (1990) Frontal lobe function in progressive supranuclear palsy. Arch Neurol 47:553–558CrossRef
76.
go back to reference VanVoorst WA, Greenaway MC, Boeve BF et al (2008) Neuropsychological findings in clinically atypical autopsy confirmed corticobasal degeneration and progressive supranuclear palsy. Park Relat Disord 14:376–378CrossRef VanVoorst WA, Greenaway MC, Boeve BF et al (2008) Neuropsychological findings in clinically atypical autopsy confirmed corticobasal degeneration and progressive supranuclear palsy. Park Relat Disord 14:376–378CrossRef
78.
go back to reference Esmonde T, Giles E, Gibson M, Hodges JR (1996) Neuropsychological performance, disease severity, and depression in progressive supranuclear palsy. J Neurol 243:638–643CrossRef Esmonde T, Giles E, Gibson M, Hodges JR (1996) Neuropsychological performance, disease severity, and depression in progressive supranuclear palsy. J Neurol 243:638–643CrossRef
89.
go back to reference Stuss DT, Alexander MP, Hamer L et al (1998) The effects of focal anterior and posterior brain lesions on verbal fluency. J Int Neuropsychol Soc 4:265–278CrossRef Stuss DT, Alexander MP, Hamer L et al (1998) The effects of focal anterior and posterior brain lesions on verbal fluency. J Int Neuropsychol Soc 4:265–278CrossRef
97.
go back to reference Pillon B, Dubois B, Lhermitte F, Agid Y (1986) Heterogeneity of cognitive impairment in progressive supranuclear palsy, Parkinson’s disease, and Alzheimer’s disease. Neurology 36:1179–1185CrossRef Pillon B, Dubois B, Lhermitte F, Agid Y (1986) Heterogeneity of cognitive impairment in progressive supranuclear palsy, Parkinson’s disease, and Alzheimer’s disease. Neurology 36:1179–1185CrossRef
98.
go back to reference McKenna P, Warrington EK (1983) Graded naming test. Nelson Publishing Co Ltd, Windsor McKenna P, Warrington EK (1983) Graded naming test. Nelson Publishing Co Ltd, Windsor
123.
go back to reference Dubois B, Pillon B (2005) Added value of the neuropsychological evaluation for diagnosis and research of atypical parkinsonian disorders. In: Litvan I (ed) Atypical Parkinsonian disorders: clinical and research aspects. Humana Press, Totowa, pp 185–195CrossRef Dubois B, Pillon B (2005) Added value of the neuropsychological evaluation for diagnosis and research of atypical parkinsonian disorders. In: Litvan I (ed) Atypical Parkinsonian disorders: clinical and research aspects. Humana Press, Totowa, pp 185–195CrossRef
124.
go back to reference Grafman J, Litvan I, Stark M (1995) Neuropsychological features of progressive supranuclear palsy. Brain Cogn 28:311–320CrossRef Grafman J, Litvan I, Stark M (1995) Neuropsychological features of progressive supranuclear palsy. Brain Cogn 28:311–320CrossRef
130.
go back to reference Duffy JR (2005) Motor speech disorders: substrates, differential diagnosis, and management, 2nd edn. Elsevier, St Louis Duffy JR (2005) Motor speech disorders: substrates, differential diagnosis, and management, 2nd edn. Elsevier, St Louis
139.
go back to reference Miller N (2017) Communication changes in Parkinson’s disease. Pract Neurol 17:266–274CrossRef Miller N (2017) Communication changes in Parkinson’s disease. Pract Neurol 17:266–274CrossRef
141.
go back to reference Taler V, Phillips NA (2008) Language performance in Alzheimer’s disease and mild cognitive impairment: a comparative review. J Clin Exp Neuropsychol 30:501–556CrossRef Taler V, Phillips NA (2008) Language performance in Alzheimer’s disease and mild cognitive impairment: a comparative review. J Clin Exp Neuropsychol 30:501–556CrossRef
144.
go back to reference Kertesz A (2006) Western aphasia battery-revised (WAB-R). Pro-Ed. Pearson, San Antonio Kertesz A (2006) Western aphasia battery-revised (WAB-R). Pro-Ed. Pearson, San Antonio
145.
go back to reference Goodglass H, Kaplan E, Barresi B (2001) Boston diagnostic aphasia examination third edition (BDAE-3). Lippincott Williams & Wilkins, Philadelphia Goodglass H, Kaplan E, Barresi B (2001) Boston diagnostic aphasia examination third edition (BDAE-3). Lippincott Williams & Wilkins, Philadelphia
Metadata
Title
Language impairment in progressive supranuclear palsy and corticobasal syndrome
Authors
Katie A. Peterson
Karalyn Patterson
James B. Rowe
Publication date
01-03-2021
Publisher
Springer Berlin Heidelberg
Published in
Journal of Neurology / Issue 3/2021
Print ISSN: 0340-5354
Electronic ISSN: 1432-1459
DOI
https://doi.org/10.1007/s00415-019-09463-1

Other articles of this Issue 3/2021

Journal of Neurology 3/2021 Go to the issue