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Acta Neuropathologica
Published in: Acta Neuropathologica 1/2020

01-01-2020 | Astrocytoma | Correspondence

Histone epiproteomic profiling distinguishes oligodendroglioma, IDH-mutant and 1p/19q co-deleted from IDH-mutant astrocytoma and reveals less tri-methylation of H3K27 in oligodendrogliomas

Authors: C. Feller, M. Felix, T. Weiss, C. Herold-Mende, F. Zhang, T. Kockmann, F. Sahm, R. Aebersold, A. von Deimling, D. E. Reuss

Published in: Acta Neuropathologica | Issue 1/2020

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Excerpt

WHO classification for tumours of the central nervous system strongly endorses molecular tests for the precise diagnosis of diffuse gliomas. Subclassification of isocitrate dehydrogenase (IDH)-mutant gliomas into IDH-mutant astrocytomas and oligodendrogliomas requires testing for complete 1p/19q co-deletion [1] in those cases not showing loss of ATRX expression [2]. …
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Literature
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Metadata
Title
Histone epiproteomic profiling distinguishes oligodendroglioma, IDH-mutant and 1p/19q co-deleted from IDH-mutant astrocytoma and reveals less tri-methylation of H3K27 in oligodendrogliomas
Authors
C. Feller
M. Felix
T. Weiss
C. Herold-Mende
F. Zhang
T. Kockmann
F. Sahm
R. Aebersold
A. von Deimling
D. E. Reuss
Publication date
01-01-2020
Publisher
Springer Berlin Heidelberg
Published in
Acta Neuropathologica / Issue 1/2020
Print ISSN: 0001-6322
Electronic ISSN: 1432-0533
DOI
https://doi.org/10.1007/s00401-019-02096-8

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