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Basic Research in Cardiology
Published in: Basic Research in Cardiology 6/2008

01-11-2008 | INVITED EDITORIAL

Impaired interaction between platelets and endothelial progenitor cells in diabetic patients

Authors: Petra Kleinbongard, PhD, Artur-Aron Weber

Published in: Basic Research in Cardiology | Issue 6/2008

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Abstract

This editorial focuses on new data on the role of platelets of the recruitment of endothelial progenitor cells to sites of vascular lesion and their differentiation into endothelium. Questions of further research are raised.
Literature
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Dernbach E, Randriamboavonjy V, Fleming I, Zeiher AM, Dimmeler S, Urbich C (2008) Impaired interaction of platelets with endothelial progenitor cells in patients with cardiovascular risk factors. Basic Res Cardiol doi:10.​1007/​s00395-008-0734-z.
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Hristov M, Weber C (2006) The therapeutic potential of progenitor cells in ischemic heart disease—past, present and future. Basic Res Cardiol 101:1–7PubMedCrossRef
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Kälsch T, Elmas E, Nguyen XD, Suvajac N, Klüter H, Borggrefe M, Dempfle CE (2007) Endotoxin-induced effects on platelets and moncytes in an in vivo model of inflammation. Basic Res Cardiol 102:460–466 PubMedCrossRef
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Keymel S, Kalka C, Rassaf T, Yeghiazarians Y, Kelm M, Heiss C (2008) Impaired endothelial progenitor cell function predicts age-dependent carotid intimal thickening. Basic Res Cardiol doi:10.​1007/​s00395-008-0742-z.
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Schuh A, Liehn EA, Sasse A, Hristov M, Sobota R, Kelm M, Merx MW, Weber C (2008) Impaired endothelial progenitor cell function predicts age-dependent carotid intimal thickening. Basic Res Cardiol 103:69–77PubMedCrossRef
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Sun C, Liang C, Ren Y, Zhen Y, He Z, Wang H, Tan H, Pan X, Wu Z (2008) Advanced glycation end products depress function of endothelial progenitor cells via p38 and ERK 1/2 mitogen-activated protein kinase pathways. Basic Res Cardiol doi:10.​1007/​s00395-008-0738-8.
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Westermann D, Linthout S, Dhayat S, Dhayat N, Schmidt A, Noutsias M Song XY, Spillmann F, Riad A, Schultheiss HP, Tschöpe C (2007) Tumor necrosis factor-alpha antagonism protects from myocardial inflammation and fibrosis in experimental diabetic cardiomyopathy. Basic Res Cardiol 102:500–507PubMedCrossRef
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Zhang C (2008) The role of inflammatory cytokines in endothelial dysfunction. Basic Res Cardiol 103:398–406PubMedCrossRef
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Zhang C, Park Y, Picchi A, Potter BJ (2008) Maturation-induces endothelial dysfunction via vascular inflammation in diabetic mice. Basic Res Cardiol 103:407–416PubMedCrossRef
Metadata
Title
Impaired interaction between platelets and endothelial progenitor cells in diabetic patients
Authors
Petra Kleinbongard, PhD
Artur-Aron Weber
Publication date
01-11-2008
Publisher
D. Steinkopff-Verlag
Published in
Basic Research in Cardiology / Issue 6/2008
Print ISSN: 0300-8428
Electronic ISSN: 1435-1803
DOI
https://doi.org/10.1007/s00395-008-0747-7

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