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European Journal of Nutrition

Published in:

01-09-2019 | Review

The effect of healthy Nordic diet on cardio-metabolic markers: a systematic review and meta-analysis of randomized controlled clinical trials

Authors: Nahid Ramezani-Jolfaie, Mohammad Mohammadi, Amin Salehi-Abargouei

Published in: European Journal of Nutrition | Issue 6/2019

Abstract

Background and aims

The Nordic diet (ND), is supposed to be associated with a reduced cardiovascular risk; however, clinical trials have led to inconsistent results regarding the effect of this diet on cardio-metabolic markers. Using systematic review and meta-analysis of randomized controlled trials (RCTs), this study aimed to investigate the effect of the ND on circulating levels of total, low-density lipoprotein (LDL), and high-density lipoprotein (HDL) cholesterol, and triglyceride (TG), as well as blood pressure in human adults.

Methods

PubMed, Scopus, ISI Web of Science, and Google Scholar were searched up to February 2018 for relevant articles. Random effects model was used to estimate the overall effects.

Results

Five RCTs consisting of 513 participants were included in the present review. The meta-analysis of five eligible studies showed that ND significantly reduces the total [weighted mean difference (WMD) = − 0.38 mmol/l, 95% confidence interval (CI) − 0.76, − 0.01, P = 0.044] and LDL cholesterol (WMD = − 0.30 mmol/l, 95% CI − 0.54, − 0.06, P = 0.013) levels compared with the control groups; however, none was seen for HDL cholesterol and TG levels. The meta-analysis of four eligible RCTs revealed that the ND significantly reduces the systolic (WMD = − 3.97 mmHg, 95% CI − 6.40, − 1.54, P = 0.001) and diastolic blood pressure (WMD = − 2.08 mmHg, 95% CI − 3.43, − 0.72, P = 0.003).

Conclusion

The Nordic dietary pattern improves blood pressure and also some of blood lipid markers and it should be considered as a healthy dietary pattern.

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Title: The effect of healthy Nordic diet on cardio-metabolic markers: a systematic review and meta-analysis of randomized controlled clinical trials
Authors: Nahid Ramezani-Jolfaie
Mohammad Mohammadi
Amin Salehi-Abargouei
Publication date: 01-09-2019
Publisher: Springer Berlin Heidelberg
Published in: European Journal of Nutrition / Issue 6/2019
Print ISSN: 1436-6207
Electronic ISSN: 1436-6215
DOI: https://doi.org/10.1007/s00394-018-1804-0

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The effect of healthy Nordic diet on cardio-metabolic markers: a systematic review and meta-analysis of randomized controlled clinical trials

Abstract

Background and aims

Methods

Results

Conclusion

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Year in Review: Heart failure and cardiomyopathies

Semaglutide benefits people with type 2 diabetes and obesity-related heart failure

Incentivised to exercise

New intervention for STEMI-related cardiogenic shock

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Keynote webinar | Spotlight on sleep in brain health

Springer Medicine

Abstract

Background and aims

Methods

Results

Conclusion

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