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01-01-2011 | Original Article

Reliability of the lung to thorax transverse area ratio as a predictive parameter in fetuses with congenital diaphragmatic hernia

Authors: Noriaki Usui, Yoshihiro Kitano, Hiroomi Okuyama, Mari Saito, Nobuyuki Morikawa, Hajime Takayasu, Tomoo Nakamura, Satoshi Hayashi, Motoyoshi Kawataki, Hiroshi Ishikawa, Keisuke Nose, Noboru Inamura, Kouji Masumoto, Haruhiko Sago

Published in: Pediatric Surgery International | Issue 1/2011

Abstract

Purpose

An accurate prenatal assessment of the patients’ severity is essential for the optimal treatment of individuals with congenital diaphragmatic hernia (CDH). The purpose of this study was to clarify the reliability of the lung to thorax transverse area ratio (L/T) as a prenatal predictive parameter.

Methods

A multicenter retrospective cohort study was conducted on 114 isolated CDH fetuses with a prenatal diagnosis during the period between 2002 and 2007 at five participating centers in Japan. The relationship between the gestational age and the L/T was analyzed. The most powerful measurement point and accurate cutoff value of the L/T was determined by an analysis of a receiver operating characteristic curve, which was verified by comparing the patients’ severity.

Results

There was a negative correlation between the gestational age and the L/T in the non-survivors, and no correlation in the survivors. There were significant differences in the parameters which represented the patients’ severity including the respiratory and circulatory status, the surgical findings, and the final outcomes between the groups divided at 0.080 in the minimum value of the L/T during gestation.

Conclusion

The L/T was not strongly influenced by the gestational age, and it was found to be a reliable prenatal predictive parameter in fetuses with isolated CDH.

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Title: Reliability of the lung to thorax transverse area ratio as a predictive parameter in fetuses with congenital diaphragmatic hernia
Authors: Noriaki Usui
Yoshihiro Kitano
Hiroomi Okuyama
Mari Saito
Nobuyuki Morikawa
Hajime Takayasu
Tomoo Nakamura
Satoshi Hayashi
Motoyoshi Kawataki
Hiroshi Ishikawa
Keisuke Nose
Noboru Inamura
Kouji Masumoto
Haruhiko Sago
Publication date: 01-01-2011
Publisher: Springer-Verlag
Published in: Pediatric Surgery International / Issue 1/2011
Print ISSN: 0179-0358
Electronic ISSN: 1437-9813
DOI: https://doi.org/10.1007/s00383-010-2725-z

Keynote webinar | Spotlight on sleep in brain health

Springer Medicine

Reliability of the lung to thorax transverse area ratio as a predictive parameter in fetuses with congenital diaphragmatic hernia

Abstract

Purpose

Methods

Results

Conclusion

Keynote webinar | Spotlight on sleep in brain health

Springer Medicine

Abstract

Purpose

Methods

Results

Conclusion

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